Brainsights will kick open the door to the enigma of our minds by looking at the latest research being carried out by an army of 50 000 neuroscientists. Using that knowledge, I will provide specific strategies to apply it to live, love and lead a better life. Breakthroughs in the tools and methods for studying the brain in the last 10 years has resulted in an outpouring of insights into human behavior and why we do the things we do. The science has turned on its head long-held beliefs, leaving us with a clearer understanding of how to influence brain-positive behaviors to promote change. Brainsights will help you to: · Understand how your brain has evolved to process the world · Re-wire your brain to break habits and foster well-being · Understand the chemistry of relationships and use it to build more meaningful connections · Use experience to promote brain growth to shape new capabilities I will strip away the inherent complexity of the science and steer you to insights that will enrich your relationships, improve your well-being, and increase your productivity. Brainsights is a thinking person’s self-help book. It is for those that can’t wait to dig into the science, knowing what awaits them is the wisdom to make a difference in their own lives and those of others. Well referenced with original research, the book is full of practical insights you can use in daily life to rewire yourself for success.

The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood–brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics are dynamic and often changed by disease/trauma. Knowledge of all these factors and their interplay in different conditions is of utmost importance for proper CNS drug development and disease treatment. In recent years much information has become available for a better understanding of the many factors important for CNS drug delivery and how they interact to affect drug action. This book describes small and large drug delivery to the brain with an emphasis on the physiology of the BBB and the principles and concepts for drug delivery across the BBB and distribution within the brain. It contains methods descriptions for studying drug delivery, routes and approaches of administering drugs into the brain, the influence of disease, drug industry perspectives, and a primer on neuroanatomy and physiological considerations written specifically for drug delivery scientists. Therewith, it contributes to an in-depth understanding of the interplay between brain (patho)-physiology and drug characteristics. Furthermore, the content is designed to be both cutting-edge and educational, so that the book can be used in high-level training of academic and industry scientists with full references to original publications.

Since becoming commercially available in 1985, transcranial magnetic stimulation (TMS) has emerged as an important tool in several areas of neuroscience. Originally envisioned as a way to measure the responsiveness and conduction speed of neurons and synapses in the brain and spinal cord, TMS has also become an important tool for changing the activity of brain neurons and the functions they subserve and an important adjunct to brain imaging and mapping techniques. Along with transcranial electrical stimulation techniques, TMS has diffused far beyond the borders of clinical neurophysiology and into cognitive, perceptual, behavioural, and therapeutic investigation and attracted a highly diverse group of users and would-be users. This book provides an authoritative review of the scientific and technical background required to understand transcranial stimulation techniques and a wide-ranging survey of their burgeoning application in neurophysiology, perception, cognition, emotion, and clinical practice. Each of its six sections deals with a major area and is edited by an international authority therein. It will serve researchers, clinicians, students, and others as the definitive text in this area for years to come.

From the first time that I painted, I had no interest to be a derivative of other artists. My driving intuition was to be influenced nonconsciously by brain insights. My privileged view of the brain, is of overseeing the data patterns of human brain function in the world’s largest brain database. My art is mainly abstract expressionism that reflects my understanding of how the human brain and behavior works. Each series of paintings continue for a few months and are driven by a different inspiration from the nonconscious-conscious dynamics of my brain. The last series in this book: “Unbridled” – is where my nonconscious brain most dominated whatever spontaneously emerged (with no preconceptions) ‘in the moment’, in each painting. I am indebted to the wide influences from my background in brain science, medicine and the international brain database that I set up. As well as the feedback and inspirations from true friends (and attendees at my exhibitions, including 2 exhibitions in New York). Further details and contact information is on the website: http://www.BRAINSightArt.com

There are many resources on grant writing in science, technology and medicine, but most do not provide the practical advice needed to write the narratives of grant proposals. Designed to help novice and experienced investigators write compelling narratives and acquire research funding, this is a detailed guide to the content, organisation, layout, phrasing, and scientific argumentation of narratives. The authors draw on more than twenty years of research and analysis of grant proposals, having worked extensively with investigators at different levels, from pre-doctoral students to senior scientists. They have used this experience to design a framework for scientific writing that you can apply directly to narratives. The guidelines and advice offered are applicable across many funding agencies, including the NIH and NSF. Featuring many real-life examples, the book covers a range of topics, from organisational alternatives to best practices in grammar and editing, overview visuals, and working with contributors.

Current Techniques in Canine and Feline Neurosurgery offers state-of-the-art, detailed guidance on performing neurosurgical techniques in dogs and cats, from indications and surgical anatomy to procedures and post-operative care. Presents an up-to-date, detailed reference on veterinary neurosurgery techniques, covering skills ranging from basic to advanced Provides guidance on why, when, and how to perform neurosurgical procedures Includes information on diagnostic evaluation, surgical planning, and instrumentation as well as step-by-step descriptions of specific procedures Copublished with the American College of Veterinary Surgeons Foundation and American College of Veterinary Internal Medicine Offers video clips on a companion website

People today use technology on different devices in different locations. Users expect to access information on all relevant screens and across multiple channels through smartphones, tablets, laptops/desktops, smart (internet-connected) TVs, and other devices, such as smartwatches for example. Multiscreen is no longer a nice add-on, it's a requirement. In this environment, user experience needs to cater to multiple devices. This book provides a holistic approach that will help UX professionals to offer a hands-on guide for UX design across multiple screens. It presents an opportunity to learn how to cater designs for customers. Readers will find patterns, strategies, examples and case studies, methodologies, and insights to help inspire them to develop a viable strategy for their own digital products and services. UX professionals will walk through important elements of multiscreen UX: - Investigating the devices and their capabilities - Understanding the users and their capabilities - Considering the context in which users use these devices - Navigating next generation information experiences and the future of content management - Designing content and UI architecture for multiscreen projects - A hands-on, practical guide to UX design for how users approach content – across more than one screen at a time - Discusses devices, users, and their practices - Includes best practices, real-world examples, and tips and tricks - A preface written by Scott Jenson

The papers in this volume consider the role of sensory-motor processes and their neural structures in higher cognitive functions such as visual and motor imagery, iconic memory and temporal judgment. The evidence brought to bear on this issue comes from behavioral studies of brain-damaged subjects and fMRI and TMS studies with normal subjects. The issue also includes several theoretical reviews and discussions.

Numerous publications have attested to the therapeutic efficacy of non-invasive brain stimulation (NIBS) techniques, such as repetitive transcranial magnetic stimulation (rTMS) and low-intensity transcranial electrical stimulation (tES). These methods have been used in the treatment of various neurological-related conditions, such as chronic pain, cognitive disorders, movement disorders, or stroke rehabilitation. Across these different fields, evidence suggests therapeutic efficacy could be improved when combining NIBS technique in combination with another type of more commonly utilized therapeutic approaches (e.g., motor and/or cognitive training, pharmacological, physical and neurorehabilitation).

The sensory and motor cortical homunculi proposed by Walter Penfield were a major landmark for the anatomical mapping of the brain. More than 60 years after, the development of new tools to investigate brain function non-invasively has increased our knowledge about the structure and functions of the primary motor Cortex (M1) beyond motor control in both humans and animals. This book highlights the role of the motor cortex that goes way beyond motor functioning. We were interested in both theoretical and empirical contributions related to electrophysiological, pharmacological, neuroimaging, and neuromodulatory studies exploring the role of M1 on non-motor functions, such as pain, abnormal neuroplasticity that may lead to chronic pain conditions; or the relationship between M1 and mental imagery or emotion. This book is comprised of 15 articles published in this edited volume as a research topic collection in Frontiers in Human Neuroscience titled “The Role of Primary Motor Cortex as a Marker and Modulator of Pain Control and Emotional-Affective Processing.”