Part visceral dream-memoir, part fictive journey through a hallucinatory Bucharest, Mircea Cărtărescu’s Blinding was one of the most widely heralded literary sensations in contemporary Romania, and a bestseller from the day of its release. Riddled with hidden passageways, mesmerizing tapestries, and whispering butterflies, Blinding takes us on a mystical trip into the protagonist’s childhood, his memories of hospitalization as a teenager, the prehistory of his family, a traveling circus, Secret police, zombie armies, American fighter pilots, the underground jazz scene of New Orleans, and the installation of the communist regime. This kaleidoscopic world is both eerily familiar and profoundly new. Readers of Blinding will emerge from this strange pilgrimage shaken, and entirely transformed. From the Trade Paperback edition.

Planning clinical research requires many decisions. The authors of this book explain key decisions with examples showing what works and what does not.

What information should jurors have during court proceedings to render a just decision? Should politicians know who is donating money to their campaigns? Will scientists draw biased conclusions about drug efficacy when they know more about the patient or study population? The potential for bias in decision-making by physicians, lawyers, politicians, and scientists has been recognized for hundreds of years and drawn attention from media and scholars seeking to understand the role that conflicts of interests and other psychological processes play. However, commonly proposed solutions to biased decision-making, such as transparency (disclosing conflicts) or exclusion (avoiding conflicts) do not directly solve the underlying problem of bias and may have unintended consequences. Robertson and Kesselheim bring together a renowned group of interdisciplinary scholars to consider another way to reduce the risk of biased decision-making: blinding. What are the advantages and limitations of blinding? How can we quantify the biases in unblinded research? Can we develop new ways to blind decision-makers? What are the ethical problems with withholding information from decision-makers in the course of blinding? How can blinding be adapted to legal and scientific procedures and in institutions not previously open to this approach? Fundamentally, these sorts of questions—about who needs to know what—open new doors of inquiry for the design of scientific research studies, regulatory institutions, and courts. The volume surveys the theory, practice, and future of blinding, drawing upon leading authors with a diverse range of methodologies and areas of expertise, including forensic sciences, medicine, law, philosophy, economics, psychology, sociology, and statistics. - Introduces readers to the primary policy issue this book seeks to address: biased decision-making. - Provides a focus on blinding as a solution to bias, which has applicability in many domains. - Traces the development of blinding as a solution to bias, and explores the different ways blinding has been employed. - Includes case studies to explore particular uses of blinding for statisticians, radiologists, and fingerprint examiners, and whether the jurors and judges who rely upon them will value and understand blinding.

The second book in the Lightbringer series, the blockbuster fantasy epic from international bestseller Brent Weeks. Perfect for fans of Brandon Sanderson, Robin Hobb and Joe Abercrombie. Gavin Guile is dying. He'd thought he had five years left - now he's got less than one. With fifty thousand refugees, a bastard son and an ex-fiancée who may have learned his darkest secret, Gavin's got problems on every side. As he loses control, the world's magic runs wild, threatening to destroy the Seven Satrapies. The old gods are being reborn and their army of colour wights is unstoppable. The only salvation may be the brother whose freedom and life Gavin stole sixteen years ago. 'Weeks has a style of immediacy and detail that pulls the reader relentlessly into the story. He doesn't allow you to look away' Robin Hobb 'Weeks writes in an inescapably engaging style' Andrea Stewart 'Weeks is a giant of the genre' Nicholas Eames 'Brent Weeks is so good it's beginning to tick me off' Peter V. Brett 'I was mesmerised from start to finish. Unforgettable characters, a plot that kept me guessing, non-stop action and the kind of in-depth storytelling that makes me admire a writers' work' Terry Brooks 'Weeks has truly cemented his place among the great epic fantasy writers of our time' British Fantasy Society Books by Brent Weeks Lightbringer The Black Prism The Blinding Knife The Broken Eye The Blood Mirror The Burning White Night Angel The Way of Shadows Shadow's Edge Beyond the Shadows The Kylar Chronicles Night Angel Nemesis Perfect Shadow: A Night Angel Novella The Way of Shadows: The Graphic Novel

Poetry. Latinx Studies. Translated by Lisa Allen Ortiz and Sara Daniele Rivera. THE BLINDING STAR collects selected new translations of poems by the Peruvian poet Blanca Varela and includes two of her most experimental works in their entirety: The Book of Clay and Animal Concert. Although Varela has been categorized as a surrealist, this collection reframes her work as existentially feminist. There is nothing arbitrary in Varela's serrated language and carnal obsessions. She is telling the story of a woman's liminal being--her body as both a vessel of expectations and a vast unmapped interior. Octavio Paz described Varela's work as "Both the wound and the knife," and this collection emphasizes the duality of her poetry. These poems journey inward through dark gardens to expose the wound of grief and outward again with sharp clarity. Blanca Varela is a singular artist, furiously searching for fragments of brightness in the merciless landscape of her own mind.

From a New York Times bestselling author comes the incredible true story of an underage soldier's first love and loss on the battlefields of Bataan and Corregidor—perfect for fans of The Boy Who Followed His Father into Auschwitz and Unbroken. Joe Johnson Jr. ran away from home at the age of 12, hopping a freight train at the height of the Great Depression. He managed to talk his way into the U.S. Army two years later. Seeking freedom and adventure, he was sent to the Philippines. Adrift in spirit, Joe visited a teenage prostitute, and they became unlikely, smitten allies. Yet when the Japanese attacked on December 8, 1941, their hopes of being together had to wait. Joe and his fellow soldiers fought for four brutal months in Bataan and Corregidor, until they were forced to surrender. The boy endured years of horror as a prisoner of war, only dreaming about seeing again the girl he’d come to love. This lyrically written and deeply encouraging saga will remind you that every life can be lifted, forgiveness is the patron of restoration, and redemption is available to all.

This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.

Today, we believe that the map is a copy of the Earth, without realizing that the opposite is true: in our culture the Earth has assumed the form of a map. In Blinding Polyphemus, Franco Farinelli elucidates the philosophical correlation between cultural evolution and shifting cartographies of modern society, giving readers an interdisciplinary study that attempts to understand and redefine the fundamental structures of cartography, architecture, and the notion of "space." Following the lessons of nineteenth-century critical German geography, this is a manual of geography without any map. To indicate where things are means already responding, in implicit and unreflective ways, to prior questions about their nature. Blinding Polyphemus not only takes account of the present state of the Earth and of human geography, it redefines the principal models we possess for the description of the world: the map, above all, as well as the landscape, subject, place, city, and space.

Colorblindness has become an integral part of the national conversation on race in America. Given the assumptions behind this influential metaphor—that being blind to race will lead to racial equality—it's curious that, until now, we have not considered if or how the blind "see" race. Most sighted people assume that the answer is obvious: they don't, and are therefore incapable of racial bias—an example that the sighted community should presumably follow. In Blinded by Sight,Osagie K. Obasogie shares a startling observation made during discussions with people from all walks of life who have been blind since birth: even the blind aren't colorblind—blind people understand race visually, just like everyone else. Ask a blind person what race is, and they will more than likely refer to visual cues such as skin color. Obasogie finds that, because blind people think about race visually, they orient their lives around these understandings in terms of who they are friends with, who they date, and much more. In Blinded by Sight, Obasogie argues that rather than being visually obvious, both blind and sighted people are socialized to see race in particular ways, even to a point where blind people "see" race. So what does this mean for how we live and the laws that govern our society? Obasogie delves into these questions and uncovers how color blindness in law, public policy, and culture will not lead us to any imagined racial utopia.

Explores creative genius and fame through the life of a writer whose search for a muse has led him into dangerous and destructive places.