Textiles play a vital role in the manufacture of various medical devices, including the replacement of diseased, injured or non-functioning organs within the body. Biotextiles as medical implants provides an invaluable single source of information on the main types of textile materials and products used for medical implants. The first part of the book focuses on polymers, fibers and textile technologies, and these chapters discuss the manufacture, sterilization, properties and types of biotextiles used for medical applications, including nanofibers, resorbable polymers and shaped biotextiles. The chapters in part two provide a comprehensive discussion of a range of different clinical applications of biotextiles, including surgical sutures, arterial prostheses, stent grafts, percutaneous heart valves and drug delivery systems.This book provides a concise review of the technologies, properties and types of biotextiles used as medical devices. In addition, it addresses the biological dimension of how to design devices for different clinical applications, providing an invaluable reference for biomedical engineers of medical textiles, quality control and risk assessment specialists, as well as managers of regulatory affairs. The subject matter will also be of interest to professionals within the healthcare system including surgeons, nurses, therapists, sourcing and purchasing agents, researchers and students in different disciplines. - Provides an invaluable single source of information on the main types of textile materials and products used for medical implants - Addresses the technologies used and discusses the manufacture, properties and types of biotextiles - Examines applications of biotextiles as medical implants, including drug delivery systems and stent grafts and percutaneous heart valves

Developing novel drug delivery systems (DDSs) from drugloaded fibers is a useful and attractive medical applications of biotextiles. This chapter reviews relevant textile technologies, types of polymers and active pharmaceutical ingredients for preparing drug-loaded fibers. Different types of DDS derived from novel drug-loaded fibers are summarized. Future trends and areas for intensive biotextiles research with reference to DDSs are discussed.

The biocompatibility, biofunctionality and biostability of a prosthesis, its degradation and the host response are determined through an implant retrieval study. This chapter focuses on various aspects of analyzing retrieved biotextile implants. Sample preparation techniques, analytical test methods and different test standards are reviewed. Some precautions and the limitations of implant retrieval studies are also discussed.

Implantation of a permanent or retrievable filter in the inferior vena cava (IVC) is becoming an increasingly popular option for patients at risk of deep vein thrombosis (DVT). This chapter discusses the size and shaping parameters for IVC filters, and considers materials that are suitable. Complications and adverse incidents are also reviewed. The chapter concludes with specifications for an ‘ideal’ IVC filter and a look at a recent new design that has recently completed clinical trials.

The chapter discusses the characteristics of resorbable polymers used for medical applications, in particular in cardiovascular systems, in terms of their biocompatibility, resorbability, mechanical and degradation properties, manufacturing feasibility, sterilizability and shelf life. Polymers currently in use for biotextile applications are surveyed, together with recent advances in mechano-active engineering of tissues, especially for blood vessel regeneration, using fibrous elastic degradable polymer scaffolds.

The chapter describes the regulatory framework applicable to medical devices, and specifically to biotextiles, principally in the United States, but also in the European Union. With the emergence of new technologies and materials, new forms of regulation have become necessary, and some of the traditional classifications no longer match present-day applications. Problems encountered by manufacturers with regard to premarket approval clearance and material supply quality standards assurance are discussed, as well as issues increasingly arising when one biotextile-based medical device is evolved into another for a different use.

Catgut and collagen are the two most well-known natural materials for absorbable sutures; however collagen-based absorbable sutures have largely been replaced by synthetic materials made from one of five basic building blocks. The chemical structures of a variety of commercial absorbable sutures are reviewed. The characteristics, chemistry and manufacture of some nonabsorbable equivalents are also considered. A number of newly available materials, in particular the group of amino-acid based biodegradable poly(ester amide) fibers, are considered, together with the results of trials.

This book provides systematic coverage of research into medical and biotextiles based on nanomaterials as applicable in healthcare. Divided into three sections, it explains manufacturing, properties, types, and recent developments in nanotechnology based medical textiles backed by case studies. It includes a wide range of different clinical applications of biotextiles for healthcare including nanotextile scaffolds, nano-based artificial organs, surgical sutures, enzymatic assisted enhanced biotextiles, tissue engineering or drug delivery system via nanofibers, and so forth. Features: Provides strong and broad overview of medical applications in the field of nano and biotextiles. Highlights different approaches, recent research, and emerging innovations. Covers designing or developing nanomaterials based antiviral surface disinfectants with self-cleaning property. Reviews different applications of nano based medical textiles such as deodorizing or pH control clothing for hygiene maintenance. Includes the real-life applications based descriptive case studies that offer a diverse range of perspectives. This book is aimed at researchers and graduate students in textile technology and engineering, and medical textiles.

Textiles are known to have unique properties that lend themselves to use in many different types of technical products, among which perhaps the best known are medical materials. Presented in this chapter are aspects of polymer, fiber and textile science that should serve as useful background knowledge of the materials used in constructing products and whose in vitro and in vivo physical and mechanical performances are discussed in this book.

Medical Textiles from Natural Resources provides systematic and comprehensive coverage of the fundamentals, production methods, processing techniques, characterization techniques, properties and applications of medical textile materials from natural resources. Medical textiles offer a variety of technical and functional properties valued in medical and healthcare sectors, often relating to hygiene. As medical textile products remain in close contact with the human body, the fibre must have characteristics such as biological compatibility, biological degradability, permeability and nontoxicity. Only materials from natural renewable sources have such characteristics. This book provides the latest information on a wide range of medical applications, from single suture and wound dressings, to implants and tissue scaffolds. It also offers a systematic review of the manufacture, properties and applications of technical textiles for medical use. - Explains the latest technologies related to fibre extraction from natural sources, chemical treatments, weave constructions, fabric finishes and coatings. - Describes innovative applications of nanomaterials in the treatment of textile fabric and the utilization of carbohydrate polymers in the preparation of nanoparticles deposited in nonwoven fabrics. - Helps product designers to find appropriate materials from natural resources with the characteristics of biodegradability, renewability, biocompatibility and nontoxicity.