Biophysical Chemistry of Proteins

Biophysical Chemistry of Proteins
Author :
Publisher : Springer Science & Business Media
Total Pages : 490
Release :
ISBN-10 : 9781441972514
ISBN-13 : 144197251X
Rating : 4/5 (14 Downloads)

Synopsis Biophysical Chemistry of Proteins by : Engelbert Buxbaum

The book is structured in nine sections, each containing several chapters. The volume starts with an overview of analytical techniques and progresses through purification of proteins; protein modification and inactivation; protein size, shape, and structure; enzyme kinetics; protein-ligand interactions; industrial enzymology; and laboratory quality control. The book is targeted at all scientists interested in protein research.

Proteins

Proteins
Author :
Publisher : Garland Science
Total Pages : 414
Release :
ISBN-10 : 9781317285434
ISBN-13 : 1317285433
Rating : 4/5 (34 Downloads)

Synopsis Proteins by : Paulo Almeida

Proteins: Concepts in Biochemistry teaches the biochemical concepts underlying protein structure, evolution, stability and folding, and explains how interactions with macromolecular structures determine protein function. Intended for a one-semester biochemistry course with a focus on proteins, this textbook emphasizes the logic underlying biophysical chemical principles. Problems throughout the book encourage statistical and quantitative thinking. The text is ideal for senior undergraduates, first year graduate students, and practitioners in chemistry, biochemistry, biology, and biophysics.

Biophysical Chemistry

Biophysical Chemistry
Author :
Publisher : Royal Society of Chemistry
Total Pages : 292
Release :
ISBN-10 : 9781847550255
ISBN-13 : 1847550258
Rating : 4/5 (55 Downloads)

Synopsis Biophysical Chemistry by : Robin Leatherbarrow

In the post-genomic world, advances in the comprehension of cell behaviour will depend upon scientists deciphering the molecular basis of interactions between proteins and membranes. Bringing together contributions from chemists, biologists and physicists, Biophysical Chemistry: Membranes and Proteins demonstrates how multidisciplinary teams can gain insights into understanding complex biological systems. This book reflects both the scope and the interdisciplinary nature of the field, with topics including: modelling of biological systems; membrane structure and interactions; probing biomolecules; and channels and receptors. Full of stimulating articles and opinions, readers from academia and industry will welcome the wide range of coverage and the state-of-the-art science.

Biophysical Characterization of Proteins in Developing Biopharmaceuticals

Biophysical Characterization of Proteins in Developing Biopharmaceuticals
Author :
Publisher : Elsevier
Total Pages : 588
Release :
ISBN-10 : 9780444641748
ISBN-13 : 0444641742
Rating : 4/5 (48 Downloads)

Synopsis Biophysical Characterization of Proteins in Developing Biopharmaceuticals by : Damian J. Houde

Biophysical Characterization of Proteins in Developing Biopharmaceuticals, Second Edition, presents the latest on the analysis and characterization of the higher-order structure (HOS) or conformation of protein based drugs. Starting from the very basics of protein structure, this book explains the best way to achieve this goal using key methods commonly employed in the biopharmaceutical industry. This book will help today's industrial scientists plan a career in this industry and successfully implement these biophysical methodologies. This updated edition has been fully revised, with new chapters focusing on the use of chromatography and electrophoresis and the biophysical characterization of very large biopharmaceuticals. In addition, best practices of applying statistical analysis to biophysical characterization data is included, along with practical issues associated with the concept of a biopharmaceutical's developability and the technical decision-making process needed when dealing with biophysical characterization data. - Presents basic protein characterization methods and tools applicable to (bio)pharmaceutical research and development - Highlights the capabilities and limitations of each technique - Discusses the underlining science of each tool - Empowers industrial biophysical chemists by providing a roadmap for applying biophysical tools - Outlines the needs for new characterization and analytical tools in the biopharmaceutical industry

Structure in Protein Chemistry

Structure in Protein Chemistry
Author :
Publisher : Garland Science
Total Pages : 913
Release :
ISBN-10 : 9781136843518
ISBN-13 : 1136843515
Rating : 4/5 (18 Downloads)

Synopsis Structure in Protein Chemistry by : Jack Kyte

The second edition of Structure in Protein Chemistry showcases the latest developments and innovations in the field of protein structure analysis and prediction. The book begins by explaining how proteins are purified and describes methods for elucidating their sequences of amino acids and defining their posttranslational modifications. Comprehensive explanations of crystallography and of noncovalent forces-ionic interactions, hydrogen bonding, and the hydrophobic effect-act as a prelude to an exhaustive description of the atomic details of the structures of proteins. The resulting understanding of protein molecular structure forms the basis for discussions of the evolution of proteins, the symmetry of the oligomeric associations that produce them, and the chemical, mathematical, and physical basis of the techniques used to study their structures. The latter include image reconstruction, nuclear magnetic resonance spectroscopy, proton exchange, optical spectroscopy, electrophoresis, covalent cross-linking, chemical modification, immunochemistry, hydrodynamics, and the scattering of light, X-radiation, and neutrons. These procedures are applied to study the folding of polypeptides and the assembly of oligomers. Biological membranes and their proteins are also discussed. Structure in Protein Chemistry, Second Edition, bridges the gap between introductory biophysical chemistry courses and research literature. It serves as a comprehensive textbook for advanced undergraduates and graduate students in biochemistry, biophysics, and structural and molecular biology. Professionals engaged in chemical, biochemical, and molecular biological research will find it a useful reference.

Biophysical Chemistry

Biophysical Chemistry
Author :
Publisher : Academic Press
Total Pages : 716
Release :
ISBN-10 : 9781483270586
ISBN-13 : 1483270580
Rating : 4/5 (86 Downloads)

Synopsis Biophysical Chemistry by : John T. Edsall

Biophysical Chemistry, Volume I: Thermodynamics, Electrostatics, and the Biological Significance of the Properties of Matter focuses on the biological aspects of the properties of matter, putting emphasis on the chemical elements, water and carbon dioxide, complex molecules, and proteins. The publication first elaborates on biochemistry and geochemistry, water and its biological significance, and the problems of protein structure. Discussions focus on the number of peptide chains in the molecule and nature of terminal groups, latent heat of fusion, characteristics of the amino acids derived from proteins, expansion of water in freezing, and the relative abundance of chemical elements in the universe. The text then takes a look at thermodynamics and the application to polar molecules and ionic solutions of electrostatics, including free energy of a charged sphere, image charges, salting-out effect, expressions for the change of fundamental thermodynamic functions, and chemical potentials. The book examines the conductivity of electrolytes, acid-base equilibria, and polybasic acids, bases, and ampholytes, including proteins. Topics include ionization of cysteine, isoelectric points of polyvalent ampholytes, hemoglobin, nature of acids and bases, measurement of conductivity, electrolytes as conductors, and the moving boundary method of determining transference numbers. The manuscript is a dependable reference for chemists and researchers interested in thermodynamics, electrostatics, and the biological value of the properties of matter.

Computational Biophysics of Membrane Proteins

Computational Biophysics of Membrane Proteins
Author :
Publisher : Royal Society of Chemistry
Total Pages : 275
Release :
ISBN-10 : 9781782626695
ISBN-13 : 1782626697
Rating : 4/5 (95 Downloads)

Synopsis Computational Biophysics of Membrane Proteins by : Carmen Domene

Exploring current themes in modern computational and membrane protein biophysics, this book presents a comprehensive account of the fundamental principles underlying different methods and techniques used to describe the intriguing mechanisms by which membrane proteins function. The book discusses the experimental approaches employed to study these proteins, with chapters reviewing recent crucial structural advances that have allowed computational biophysicists to discern how these molecular machines work. The book then explores what computational methods are available to researchers and what these have taught us about three key families of membrane proteins: ion channels, transporters and receptors. The book is ideal for researchers in computational chemistry and computational biophysics.

The Biophysical Chemistry of Nucleic Acids & Proteins

The Biophysical Chemistry of Nucleic Acids & Proteins
Author :
Publisher : Damaris Publishing
Total Pages : 774
Release :
ISBN-10 : 0956478115
ISBN-13 : 9780956478115
Rating : 4/5 (15 Downloads)

Synopsis The Biophysical Chemistry of Nucleic Acids & Proteins by : Thomas E. Creighton

DNA, RNA and proteins are undoubtedly the most important biological molecules. Being large macromolecules, their physical, chemical and biological properties can differ from those of the monomers from which they are made. This book describes their structures, origins and other key issues.

Introduction to Biophysical Methods for Protein and Nucleic Acid Research

Introduction to Biophysical Methods for Protein and Nucleic Acid Research
Author :
Publisher : Academic Press
Total Pages : 528
Release :
ISBN-10 : 9780080534985
ISBN-13 : 0080534988
Rating : 4/5 (85 Downloads)

Synopsis Introduction to Biophysical Methods for Protein and Nucleic Acid Research by : Jay A. Glasel

The first of its kind, Introduction to Biophysical Methods for Protein and Nucleic Acid Research serves as a text for the experienced researcher and student requiring an introduction to the field. Each chapter presents a description of the physical basis of the method, the type of information that may be obtained with the method, how data should be analyzed and interpreted and, where appropriate, practical tips about procedures and equipment.Key Features* Modern Use of Mass Spectroscopy* NMR Spectroscopy* Molecular Modeling and Graphics* Macintosh and DOS/Windows 3.x disks

Protein Actions: Principles and Modeling

Protein Actions: Principles and Modeling
Author :
Publisher : Garland Science
Total Pages : 337
Release :
ISBN-10 : 9781351815017
ISBN-13 : 1351815016
Rating : 4/5 (17 Downloads)

Synopsis Protein Actions: Principles and Modeling by : Ivet Bahar

Protein Actions: Principles and Modeling is aimed at graduates, advanced undergraduates, and any professional who seeks an introduction to the biological, chemical, and physical properties of proteins. Broadly accessible to biophysicists and biochemists, it will be particularly useful to student and professional structural biologists and molecular biophysicists, bioinformaticians and computational biologists, biological chemists (particularly drug designers) and molecular bioengineers. The book begins by introducing the basic principles of protein structure and function. Some readers will be familiar with aspects of this, but the authors build up a more quantitative approach than their competitors. Emphasizing concepts and theory rather than experimental techniques, the book shows how proteins can be analyzed using the disciplines of elementary statistical mechanics, energetics, and kinetics. These chapters illuminate how proteins attain biologically active states and the properties of those states. The book ends with a synopsis the roles of computational biology and bioinformatics in protein science.