Biological Barriers to Protein Delivery

Biological Barriers to Protein Delivery
Author :
Publisher : Springer Science & Business Media
Total Pages : 526
Release :
ISBN-10 : 0306443686
ISBN-13 : 9780306443688
Rating : 4/5 (86 Downloads)

Synopsis Biological Barriers to Protein Delivery by : Kenneth L. Audus

A current and critical review of information regarding peptide and protein transport and metabolism as it relates to delivery of endogenous (physiological ligands) and recombinant proteins to mammalian organs, tissues, and cells. Each chapter emphasizes mechanisms of transport including quantitative evidence and structure/function (cause/effect) relationships. The volume is intended to be a comprehensive, state-of-the-art treatise for use by academic and industrial scientists who either are just beginning or are entrenched in the field of protein drug delivery. Annotation copyright by Book News, Inc., Portland, OR

Peptide and Protein Delivery

Peptide and Protein Delivery
Author :
Publisher : Academic Press
Total Pages : 381
Release :
ISBN-10 : 9780123849366
ISBN-13 : 0123849365
Rating : 4/5 (66 Downloads)

Synopsis Peptide and Protein Delivery by : Chris Van Der Walle

The growing area of peptide and protein therapeutics research is of paramount importance to medical application and advancement. A needed reference for entry level researchers and researchers working in interdisciplinary / collaborative projects, Peptide and Protein Delivery addresses the current and emerging routes for delivery of therapeutics. Covering cerebral delivery, pulmonary delivery, transdermal delivery, intestinal delivery, ocular delivery, parenteral delivery, and nasal delivery, this resource offers an overview of the main routes in therapeutics. Researchers across biochemistry, pharmaceutical, molecular biology, cell biology, immunology, chemistry and biotechnology fields will find this publication invaluable for peptide and protein laboratory research. - Discusses the most recent data, ideas and concepts - Presents case studies and an industrial perspective - Details information from the molecular level to bioprocessing - Thought provoking, for the novice to the specialist - Timely, for today's biopharmaceuticals market

Biological Barriers to Protein Delivery

Biological Barriers to Protein Delivery
Author :
Publisher : Springer Science & Business Media
Total Pages : 507
Release :
ISBN-10 : 9781461528982
ISBN-13 : 1461528984
Rating : 4/5 (82 Downloads)

Synopsis Biological Barriers to Protein Delivery by : Kenneth L. Andus

In response to the tremendous increase in the number of protein and peptide drugs, this treatise critically reviews transport and metabolism mechanisms relating to the delivery of endogenous and recombinant proteins to mammalian organs, tissues, and cells. It will promote fruitful collaboration among academic and industrial scientists in the fields of pharmacology, cell biology, biochemistry, physiology, and immunology.

Drug Delivery

Drug Delivery
Author :
Publisher : John Wiley & Sons
Total Pages : 740
Release :
ISBN-10 : 9781118833360
ISBN-13 : 1118833368
Rating : 4/5 (60 Downloads)

Synopsis Drug Delivery by : Binghe Wang

Following its successful predecessor, this book covers the fundamentals, delivery routes and vehicles, and practical applications of drug delivery. In the 2nd edition, almost all chapters from the previous are retained and updated and several new chapters added to make a more complete resource and reference. • Helps readers understand progress in drug delivery research and applications • Updates and expands coverage to reflect advances in materials for delivery vehicles, drug delivery approaches, and therapeutics • Covers recent developments including transdermal and mucosal delivery, lymphatic system delivery, theranostics • Adds new chapters on nanoparticles, controlled drug release systems, theranostics, protein and peptide drugs, and biologics delivery

Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids

Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids
Author :
Publisher : CRC Press
Total Pages : 708
Release :
ISBN-10 : 9780203492321
ISBN-13 : 0203492323
Rating : 4/5 (21 Downloads)

Synopsis Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids by : Ram I. Mahato

Newcomers to the field of biopharmaceuticals require an understanding of the basic principles and underlying methodology involved in developing protein- and nucleic acid-based therapies for genetic and acquired diseases. Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids introduces the principles of polymer science and che

Nanostructured Biomaterials for Overcoming Biological Barriers

Nanostructured Biomaterials for Overcoming Biological Barriers
Author :
Publisher : Royal Society of Chemistry
Total Pages : 643
Release :
ISBN-10 : 9781849733632
ISBN-13 : 1849733635
Rating : 4/5 (32 Downloads)

Synopsis Nanostructured Biomaterials for Overcoming Biological Barriers by : Maria Jose Alonso

This book provides a critical overview of the advances being made toward overcoming biological barriers through the contribution of nanosciences and nanotechnologies to solve the problems of many current drugs and vaccines.

Physical Methods to Characterize Pharmaceutical Proteins

Physical Methods to Characterize Pharmaceutical Proteins
Author :
Publisher : Boom Koninklijke Uitgevers
Total Pages : 398
Release :
ISBN-10 : 0306450267
ISBN-13 : 9780306450266
Rating : 4/5 (67 Downloads)

Synopsis Physical Methods to Characterize Pharmaceutical Proteins by : James N. Herron

This collection of state-of-the-art research describes the most frequently used techniques for structural analysis of proteins. Chapters focus on the impressive progress that has been made in the development of these techniques and identify future trends and research needs. Papers feature several spectroscopic techniques-including fluorescence spectroscopy, circular dichroism, and infrared spectroscopy.

Drug Delivery Across Physiological Barriers

Drug Delivery Across Physiological Barriers
Author :
Publisher : CRC Press
Total Pages : 410
Release :
ISBN-10 : 9789814669412
ISBN-13 : 9814669415
Rating : 4/5 (12 Downloads)

Synopsis Drug Delivery Across Physiological Barriers by : Silvia Muro

Transport of pharmaceutical agents in the body is paramount to therapeutic efficacy. Advances in the past decades have rendered a remarkable improvement of drug delivery strategies, which has helped to increase the bioavailability of therapeutic agents by protecting them from degradation, targeting them to diseased sites, and controlling their circ

Fundamentals of Drug Delivery

Fundamentals of Drug Delivery
Author :
Publisher : John Wiley & Sons
Total Pages : 580
Release :
ISBN-10 : 9781119769606
ISBN-13 : 1119769604
Rating : 4/5 (06 Downloads)

Synopsis Fundamentals of Drug Delivery by : Heather A. E. Benson

A comprehensive guide to the current research, major challenges, and future prospects of controlled drug delivery systems Controlled drug delivery has the potential to significantly improve therapeutic outcomes, increase clinical benefits, and enhance the safety of drugs in a wide range of diseases and health conditions. Fundamentals of Drug Delivery provides comprehensive and up-to-date coverage of the essential principles and processes of modern controlled drug delivery systems. Featuring contributions by respected researchers, clinicians, and pharmaceutical industry professionals, this edited volume reviews the latest research in the field and addresses the many issues central to the development of effective, controlled drug delivery. Divided in three parts, the book begins by introducing the concept of drug delivery and discussing both challenges and opportunities within the rapidly evolving field. The second section presents an in-depth critique of the common administration routes for controlled drug delivery, including delivery through skin, the lungs, and via ocular, nasal, and otic routes. The concluding section summarizes the current state of the field and examines specific issues in drug delivery and advanced delivery technologies, such as the use of nanotechnology in dermal drug delivery and advanced drug delivery systems for biologics. This authoritative resource: Covers each main stage of the drug development process, including selecting pharmaceutical candidates and evaluating their physicochemical characteristics Describes the role and application of mathematical modelling and the influence of drug transporters in pharmacokinetics and drug disposition Details the physiology and barriers to drug delivery for each administration route Presents a historical perspective and a look into the possible future of advanced drug delivery systems Explores nanotechnology and cell-mediated drug delivery, including applications for targeted delivery and toxicological and safety issues Includes comprehensive references and links to the primary literature Edited by a team of of internationally-recognized experts, Fundamentals of Drug Delivery is essential reading for researchers, industrial scientists, and advanced students in all areas of drug delivery including pharmaceutics, pharmaceutical sciences, biomedical engineering, polymer and materials science, and chemical and biochemical engineering.