This book analyzes different facets of anuran amphibian distribution in South America. We integrate alternative biological metrics employing cutting-edge methods to understand the dynamic processes underlying species distribution patterns. By using the modern biogeographic toolbox, we explore how richness gradients, phylogenetic diversity, functional diversity, and range size/endemism distribution of amphibians vary along the continent. Moreover, we present a robust proposal for priority areas for conservation of anurans in South America that maximizes representativeness of distinct biodiversity facets.

"Rather than favoring only one approach, Juan J. Morrone proposes a comprehensive treatment of the developments and theories of evolutionary biogeography. Evolutionary biogeography uses distributional, phylogenetic, molecular, and fossil data to assess the historical changes that have produced current biotic patterns. Panbiogeography, parsimony analysis of endemicity, cladistic biogeography, and phylogeography are the four recent and most common approaches. Many conceive of these methods as representing different "schools," but Morrone shows how each addresses different questions in the various steps of an evolutionary biogeographical analysis. Panbiogeography and parsimony analysis of endemicity are useful for identifying biotic components or areas of endemism. Cladistic biogeography uses phylogenetic data to determine the relationships between these biotic components. Further information on fossils, phylogeographic patterns, and molecular clocks can be incorporated to identify different cenocrons. Finally, available geological knowledge can help construct a geobiotic scenario that may explain how analyzed areas were put into contact and how the biotic components and cenocrons inhabiting them evolved. Morrone compares these methods and employs case studies to make it clear which is best for the question at hand. Set problems, discussion sections, and glossaries further enhance classroom use."--Publisher's description.

Sweet, University of California, Santa Barbara; Michael J. Tyler, University of Adelaide, Australia; Zhao Er-Mi, Chengdu Institute of Biology, Peoples Republic of China

Now reissued in paperback with an updated preface by the authors, Biology of Amphibians remains the standard work in its field.

Though biogeography may be simply defined--the study of the geographic distributions of organisms--the subject itself is extraordinarily complex, involving a range of scientific disciplines and a bewildering diversity of approaches. For convenience, biogeographers have recognized two research traditions: ecological biogeography and historical biogeography. This book makes sense of the profound revolution that historical biogeography has undergone in the last two decades, and of the resulting confusion over its foundations, basic concepts, methods, and relationships to other disciplines of comparative biology. Using case studies, the authors explain and illustrate the fundamentals and the most frequently used methods of this discipline. They show the reader how to tell when a historical biogeographic approach is called for, how to decide what kind of data to collect, how to choose the best method for the problem at hand, how to perform the necessary calculations, how to choose and apply a computer program, and how to interpret results.

A fascinating analysis of the main patterns of distribution and evolution of the Australasian biota.

Natural Molecules in Neuroprotection and Neurotoxicity brings together research in the area of natural compounds and their dual effects of neuroprotection and neurotoxicity when interacting with brain cells. This book is organized into four sections that address molecular mechanism underlying neuroprotection and neurotoxicity, neuroprotection mediated by natural molecules, neurotoxicity induced by natural compounds and nanotechnology-related strategies utilized in neuroprotection. Written by well-known researchers all over the world, chapters provide an in-depth analysis of numerous molecules, such as algae, plant and fungus-derived molecules, and comprehensively discuss their mechanisms of action and possible clinical applications. This book provides an essential reference for researchers and clinical scientists interested in the effects of natural compounds on the human health and disease. - Covers both neuroprotective and neurotoxic outcomes resulted from the exposure of brain cells to natural molecules - Analyzes numerous natural compounds, including animal, vegetal, fungal, bacterial, and marine-derived molecules - Discusses the effects of the metabolism of microbiota on the biotransformation of natural molecules and the consequences of these processes on brain cells - Contains a section focused on the nanotechnology-related strategies utilized to enhance the bioavailability of natural molecules to brain cells

South American ecosystems suffered one of the greatest biogeographical events, after the establishment of the Panamian land bridge, called the “Great American Biotic Interchange” (GABI). This refers to the exchange, in several phases, of land mammals between the Americas; this event started during the late Miocene with the appearance of the Holartic Procyonidae (Huayquerian Age) in South America and continues today. The major phases of mammalian dispersal occurred from the Latest Pliocene (Marplatan Age) to the Late Pleistocene (Lujanian Age). The most important and richest localities of Late Miocene-Holocene fossil vertebrates of South America are those of the Pampean region of Argentina. There are also several Late Miocene and Pliocene localities in western Argentina and Bolivia. Other important fossils have been collected in localities of Pleistocene age outside Argentina: Tarija (Bolivia), karstic caves of Lagoa Santa and the recently explored caves of Tocantins (Brasil), Talara (Perú), La Carolina (Ecuador), Muaco (Venezuela), and Cueva del Milodon (Chile), among others. The book discusses basic information for interpreting the GABI such as taxonomic composition (incorporating the latest revisions) at classical and new localities for each stage addressing climate, environments, and time boundaries for each stage. It includes the chronology and dynamics of the GABI, the integration of South American mammalian faunas through time, the Quaternary mammalian extinctions and the composition of recent mammalian fauna of the continent.

Antimicrobial Peptides: Challenges and Future Perspectives covers the latest developments about antimicrobial peptides in the scenario of drug resistance. The book is divided into 16 chapters arranged in sequence and preceded by chapters on historical developments and their role as regulatory molecules in innate defense mechanism. Emphasis is given to purification techniques and characterization suitable for interdisciplinary research. Chapters provide an inventory of various antimicrobial peptides, from a diverse array of organisms such as bacteria, fungi, insects, amphibians, plants and mammals. A section on marine ecosystem broadens readers understanding on marine based antimicrobial peptides. Additional sections provide an informative overview on peptides with antiviral properties and those targeting multi-drug resistant bacteria. Recent reports and mechanism on resistance against antimicrobial peptides are also provided, along with key insights into the challenges and future perspectives of peptide drug development. - Emphasizes antimicrobial peptides targeting various human viruses and multidrug resistant bacteria - Written by internationally recognized experts who provide readers with a wide and useful perspective - Provides in-depth resources for undertaking a research work in antimicrobial peptides with the inclusion of chapters on purification techniques and structural details - Addresses the possibility and availability of peptide antibiotics in the global drug market - Serves as a complete resource from the discovery to drug development of peptide antibiotics