The “bioelectronic nose”, the device which has a similar function to the human smell sensing system, can be realized by combining the olfactory cells or receptors with nanotechnology. In the last two decades, much has been learned about the smell sensing mechanism in biological systems. With knowledge about the biological olfactory system and the techniques for the expression of biological receptor proteins, we are able to utilize biological materials and systems to mimic the biological olfactory system. In addition to the advances in biological and biotechnological area, nanotechnology has progressed to a great degree. The bioelectronic nose is a good example of the integration of biotechnology and nanotechnology. This book describes basic biological sciences of the olfactory system, biotechnology for the production of olfactory biological elements, and nanotechnology for the development of various sensing devices. The purpose of this book is to provide the reader with a concept, basic sciences, fundamental technologies, applications, and perspectives of the bioelectronic nose.

This book provides the basics of odor, odor analysis techniques, sensors used in odor analysis and overview of odor measurement techniques. For beginners as well researchers this book is a brief guide for odor measurement and analysis. The book includes a special chapter dedicated to practical implementation of e-nose sensor devices with software utility, which guides students to prepare projects and work in practical analysis. It also includes material from early to latest technology research available in the market of e-nose era. Students and researchers who want to learn the basics of biomedical engineering and sensor measurement technology will find this book useful.

Electronic Noses and Tongues in Food Science describes the electronic products of advanced chemical and physical sciences combined with intuitive integration of microprocessors, advanced bioinformatics and statistics. These include, for example, voltammetric, bio-electronic, piezoelectric platforms made from a variety of components including, nanoparticles, enzyme biosensors, heavy metals, graphite-epoxy composites, metal oxide semiconductors, microelectrodes, microfluidic channels, pre-manufactured gas sensors, redox enzymes and others and is an ideal resource for understanding and utilizing their power in Food Science settings. Devices used to analyse one particular food item can theoretically be adapted for other food items or components. This does not just mean the re-deploying the physical platforms but also the mode of bioinformatic and statistical analysis. This includes artificial neural networks (ANN), linear discriminant analysis (LDA), partial least squares (PLS), principal component analysis (PCA) etc. In other words, there is cross transference of chemistry, physics, concepts, techniques, findings and approaches from one food to another. Electronic noses and tongues are two of these devices but are advancing in application and importance. This book provides examples of the use of electronic noses and tongues to characterise components that contribute to sensory or compositional profiles, from ripening to harvesting and from storage of raw materials to packaging and consumption. These devises are suitable for high-throughput analysis, quality control or to determine the nature and extent of spoilage and adulteration, and have also been used to ascertain the geographical origins of food and mixtures. - Presents latest developments in the application of electronic nose and tongue technologies to a variety of food-specific needs - Includes both electronic nose, electronic tongue and combined technology insights - Each chapter has sections on: The physical and chemical platforms; Analysis of specific foods; Applications to other foods and areas of food science

Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing p

Provides an introduction to the topic of smart chemical sensors, along with an overview of the state of the art based on potential applications This book presents a comprehensive overview of chemical sensors, ranging from the choice of material to sensor validation, modeling, simulation, and manufacturing. It discusses the process of data collection by intelligent techniques such as deep learning, multivariate analysis, and others. It also incorporates different types of smart chemical sensors and discusses each under a common set of sub-sections so that readers can fully understand the advantages and disadvantages of the relevant transducers—depending on the design, transduction mode, and final applications. Smart Sensors for Environmental and Medical Applications covers all major aspects of the field of smart chemical sensors, including working principle and related theory, sensor materials, classification of respective transducer type, relevant fabrication processes, methods for data analysis, and suitable applications. Chapters address field effect transistors technologies for biological and chemical sensors, mammalian cell–based electrochemical sensors for label-free monitoring of analytes, electronic tongues, chemical sensors based on metal oxides, metal oxide (MOX) gas sensor electronic interfaces, and more. Addressing the limitations and challenges in obtaining state-of-the-art smart biochemical sensors, this book: Balances the fundamentals of sensor design, fabrication, characterization, and analysis with advanced methods Categorizes sensors into sub-types and describes their working, focusing on prominent applications Describes instrumentation and IoT networking methods of chemical transducers that can be used for inexpensive, accurate detection in commercialized smart chemical sensors Covers monitoring of food spoilage using polydiacetylene- and liposome-based sensors; smart and intelligent E-nose for sensitive and selective chemical sensing applications; odor sensing system; and microwave chemical sensors Smart Sensors for Environmental and Medical Applications is an important book for senior-level undergraduate and graduate students learning about this high-performance technology and its many applications. It will also inform practitioners and researchers involved in the creation and use of smart sensors.

Nanotechnology-based E-Noses reviews advances in nanomaterials and their modification for use in e-sensors. "E-noses" or "electronic sensors" are emerging as advanced technologies for the fast detection of chemicals, gases, and explosives. The concept behind the "e-nose" is similar to the capability of humans and dogs in detecting materials based on odors. Nanomaterials can be used for e-nose technologies but their properties must be modified to make them effective sensors. The sensing capability and performance of these materials depend on several factors, such as morphology, dopants, microadditives, design of sensors, phase, and structure of the nanomaterials. Theoretical understanding of nanomaterials and technologies for improving sensors with better detection limits are covered. The most relevant nanomaterials, their synthesis strategies, and the relationship between properties and device performance are provided. Current state-of-the-art progress in nanotechnology device fabrication along with directions for future applications and challenges are discussed. - Covers fundamentals of nanomaterials for electronic sensing applications, including material synthesis and property optimization strategies to improve material performance - Reviews emerging relevant nanomaterials including 1D, 2D and 3D nanomaterials for use in e-nose technologies - Discusses nanotechnology-based e-noses and their wide range of applications in the detection of chemicals, gases, explosives, and more

The book provides a single volume covering detailed descriptions about various delivery systems, their principles and how these are put in use for the treatment of multiple diseases. It is divided into four sections where the first section deals with the introduction and importance of novel drug delivery system. The second section deals with the most advanced drug delivery systems like microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions etc., describing the major principles and techniques of the preparations of the drug delivery systems. The third section elaborates on the treatments of diverse diseases like cancer, topical diseases, tuberculosis etc. The fourth and final section provides a brief informative description about the regulatory aspects of novel drug delivery system that is followed in various countries.

Master simple to advanced biomaterials and structures with this essential text. Featuring topics ranging from bionanoengineered materials to bio-inspired structures for spacecraft and bio-inspired robots, and covering issues such as motility, sensing, control and morphology, this highly illustrated text walks the reader through key scientific and practical engineering principles, discussing properties, applications and design. Presenting case studies for the design of materials and structures at the nano, micro, meso and macro-scales, and written by some of the leading experts on the subject, this is the ideal introduction to this emerging field for students in engineering and science as well as researchers.

With more than 40 contributions from expert authors, this is an extensive overview of all important research topics in the field of bioengineering, including metabolic engineering, biotransformations and biomedical applications. Alongside several chapters dealing with biotransformations and biocatalysis, a whole section is devoted to biofuels and the utilization of biomass. Current perspectives on synthetic biology and metabolic engineering approaches are presented, involving such example organisms as Escherichia coli and Corynebacterium glutamicum, while a further section covers topics in biomedical engineering including drug delivery systems and biopharmaceuticals. The book concludes with chapters on computer-aided bioprocess engineering and systems biology. This is a part of the Advanced Biotechnology book series, covering all pertinent aspects of the field with each volume prepared by eminent scientists who are experts on the topic in question. Invaluable reading for biotechnologists and bioengineers, as well as those working in the chemical and pharmaceutical industries. Advanced Biotechnology Biotechnology is a broad, interdisciplinary field of science, combining biological sciences and relevant engineering disciplines, that is becoming increasingly important as it benefits the environment and society as a whole. Recent years have seen substantial advances in all areas of biotechnology, resulting in the emergence of brand new fields. To reflect this progress, Sang-Yup Lee (KAIST, South Korea), Jens Nielsen (Chalmers University, Sweden), and Gregory Stephanopoulos (MIT, USA) have joined forces as the editors of a new Wiley-VCH book series. Advanced Biotechnology will cover all pertinent aspects of the field and each volume will be prepared by eminent scientists who are experts on the topic in question.

Introduction to Machine Olfaction Devices discusses the various aspects of a MOD device, from historical approaches to state-of-the-art technologies. This book also covers the mechanism in dealing and detecting gases, odor, and aroma. Problems and solutions relevant to present day design have been outlined as well as a step-by-step guide to Machine Olfaction Device (MOD) design. Sensors and gas systems, along with polymers and certain manufacturing processes, have been discussed, together with other relevant materials for the MOD process and functions including comparison and validations, data processing, data analysis, MOD new design, micro systems, and monitoring systems. Aimed at developing a novel and improved MOD with more efficient on-board data processing capability for monitoring applications, this book will help you to design an MOD with - a faster stabilizing base line; - a quicker sample result display; - an ability to use ambient air; - a low power consumption; and - the ability to deal with different varieties of organic/inorganic samples. With a focus on the most important and relevant aspects of designing MODs which currently require a solution, topics covered include MOD and market issues, cost, technical issues, and MOD applications. With a huge range of potential applications, this book will be of special interest to those working (or studying) in this field at every level, from Biomedical, Energy, or Electrical Engineers, to Computer or Food Scientists. Introduction to Machine Olfaction Devices discusses the various aspects of a MOD device, from historical approaches to state-of-the-art technologies. This book also covers the mechanism in dealing and detecting gases, odor, and aroma. Problems and solutions relevant to present day design have been outlined as well as a step-by-step guide to Machine Olfaction Device (MOD) design. Sensors and gas systems, along with polymers and certain manufacturing processes, have been discussed, together with other relevant materials for the MOD process and functions including comparison and validations, data processing, data analysis, MOD new design, micro systems, and monitoring systems. Aimed at developing a novel and improved MOD with more efficient on-board data processing capability for monitoring applications, this book will help you to design an MOD with - a faster stabilizing base line; - a quicker sample result display; - an ability to use ambient air; - a low power consumption; and - the ability to deal with different varieties of organic/inorganic samples. With a focus on the most important and relevant aspects of designing MODs which currently require a solution, topics covered include MOD and market issues, cost, technical issues, and MOD applications. With a huge range of potential applications, this book will be of special interest to those working (or studying) in this field at every level, from Biomedical, Energy, or Electrical Engineers, to Computer or Food Scientists. - Focuses on the most important and relevant aspects of designing machine olfaction devices (MOD) which currently require a solution - Topics covered include: MOD and market issues; MOD and cost; MOD and technical issues; MOD applications