This text applies engineering science and technology to biological cells and tissues that are electrically conducting and excitable. It describes the theory and a wide range of applications in both electric and magnetic fields.

Many vital medical techniques are based on fundamental bioelectric and biomagnetic phenomena-electrocardiographs and cardiac pacemakers are two examples. This book examines the fundamental science underlying these techniques.

This book presents an overview of the field of bioelectricity by demonstrating the biological significance of electromagnetic fields, electrical properties of tissue, biological effects of electromagnetic energy, and therapeutic applications and health hazards of electromagnetic energy.

Biomagnetism is the study of magnetic fields that originate in biological systems. This is a relatively new discipline that has attracted considerable interest throughout the scientific commu- ty. The study of biomagnetic fields requires the use of techniques and concepts drawn from widely disparate scientific disciplines. To make these techniques and concepts available to a wide spectrum of the scientific community, a NATO Advanced study Institute on B- magnetism was held near Frascati at Grottaferrata, Italy, in S- tember 1982. This volume is based on the lectures delivered by scholars representing many different scientific areas, ranging from solid state physics to psychology. It attempts to preserve the - herent development of concepts drawn from physiology, psychology, biology, physics, medicine, occupational health and geology that was evident during the Institute. The reader will quickly become aware that the progress in biomagnetism over the past decade was due principally to the efforts of interdisciplinary teams of sci- tists. One of the purposes of this volume is to make all of the basic principles and findings of biomagnetism available in one place, so that scientists who have already embarked on the study of biomagnetism or who plan to do so in the near future will have them available for study and reference. Each section of this volume was written by a recognized expert who lectured at the Institute on the topics he describes here.

Biomedical transducers are essential instruments for acquiring many types of medical and biological data. From the underlying principles to practical applications, this new book provides an easy- to-understand introduction to the various kinds of biomedical transducers. The first comprehensive treatment of this subject in 20 years, the book presents state-of-the-art information including: discussions of biomedical transducers for measurements of pressure, flow, motion, temperature, heat flow, evaporation, biopotential, biomagnetism, and chemical quantities. Chapters are devoted to particular areas of instrumentation needs

Magnetoencephalography (MEG) is an invaluable functional brain imaging technique that provides direct, real-time monitoring of neuronal activity necessary for gaining insight into dynamic cortical networks. Our intentions with this book are to cover the richness and transdisciplinary nature of the MEG field, make it more accessible to newcomers and experienced researchers and to stimulate growth in the MEG area. The book presents a comprehensive overview of MEG basics and the latest developments in methodological, empirical and clinical research, directed toward master and doctoral students, as well as researchers. There are three levels of contributions: 1) tutorials on instrumentation, measurements, modeling, and experimental design; 2) topical reviews providing extensive coverage of relevant research topics; and 3) short contributions on open, challenging issues, future developments and novel applications. The topics range from neuromagnetic measurements, signal processing and source localization techniques to dynamic functional networks underlying perception and cognition in both health and disease. Topical reviews cover, among others: development on SQUID-based and novel sensors, multi-modal integration (low field MRI and MEG; EEG and fMRI), Bayesian approaches to multi-modal integration, direct neuronal imaging, novel noise reduction methods, source-space functional analysis, decoding of brain states, dynamic brain connectivity, sensory-motor integration, MEG studies on perception and cognition, thalamocortical oscillations, fetal and neonatal MEG, pediatric MEG studies, cognitive development, clinical applications of MEG in epilepsy, pre-surgical mapping, stroke, schizophrenia, stuttering, traumatic brain injury, post-traumatic stress disorder, depression, autism, aging and neurodegeneration, MEG applications in cognitive neuropharmacology and an overview of the major open-source analysis tools.

Vector analysis. Electrical sources and fields. Introduction to membrane biophysics. Action potentials. Propagation. Subthreshold stimuli. Extracelular fields. Membrane biophysics. The electrophysiology of the heart. The neuromuscular junction. Skeletal muscle. Functional neuromuscular stimulation.

The living body is a difficult object to measure: accurate measurements of physiological signals require sensors and instruments capable of high specificity and selectivity that do not interfere with the systems under study. As a result, detailed knowledge of sensor and instrument properties is required to be able to select the "best" sensor from o

Bioelectric and Biomagnetic Fields: Theory and Applications in Electrocardiology begins with a general description of the development of extracellular bioelectric and biomagnetic fields and the methods used in their analysis and measurement. The most effective electrodynamic models and most modern approaches to topographical (synchronous multilead) measurements of the field are reviewed. The next section discusses the major approaches to analysis of the inverse problem with a detailed description of multipole technique applied to the bioelectric and biomagnetic fields measured on or near the body surface. Special emphasis is placed on the interrelationship between the electric and magnetic fields of the same bioelectric generator. The last section explains the new approaches to chronotopographical representation of the electrophysiological characteristics deduced from the parameters of the bioelectric generator. The text includes the most recent experimental protocols and results from studies in electro- and magnetocardiology and electro- and magnetoneurology.