Biodegradable Hydrogels For Drug Delivery
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Author |
: Haesun Park |
Publisher |
: CRC Press |
Total Pages |
: 272 |
Release |
: 2011-07-08 |
ISBN-10 |
: 1439892962 |
ISBN-13 |
: 9781439892961 |
Rating |
: 4/5 (62 Downloads) |
Synopsis Biodegradable Hydrogels for Drug Delivery by : Haesun Park
From the Authors' Preface The advances made in the area of controlled drug delivery during the last two decades are remarkable ....Of the many polymeric materials, biodegradable hydrogels present unique advantages and opportunities in the development of ...delivery devices....We have undertaken the challenge of putting together information relevant to biodegradable hydrogels in one place. This book covers the mechanisms of biodegradation, types of biodegradable hydrogels,chemical and physical gels, chemical and enzymatic degradation, and examples of biodegradable drug delivery systems.
Author |
: Sun Namkung |
Publisher |
: |
Total Pages |
: 342 |
Release |
: 2004 |
ISBN-10 |
: CORNELL:31924090208996 |
ISBN-13 |
: |
Rating |
: 4/5 (96 Downloads) |
Synopsis Synthesis and Characterization of Partially Biodegradable Hydrogels as a Drug Delivery System by : Sun Namkung
Author |
: Yeli Zhang |
Publisher |
: |
Total Pages |
: 580 |
Release |
: 2000 |
ISBN-10 |
: CORNELL:31924087290395 |
ISBN-13 |
: |
Rating |
: 4/5 (95 Downloads) |
Synopsis Synthesis, Characterization, and Property Study of Hydrophilic-hydrophobic Biodegradable Hydrogels as a Controlled Drug Delivery System by : Yeli Zhang
Author |
: Raphael M. Ottenbrite |
Publisher |
: Springer Science & Business Media |
Total Pages |
: 438 |
Release |
: 2010-09-05 |
ISBN-10 |
: 9781441959195 |
ISBN-13 |
: 144195919X |
Rating |
: 4/5 (95 Downloads) |
Synopsis Biomedical Applications of Hydrogels Handbook by : Raphael M. Ottenbrite
Hydrogels are networks of polymer chains which can produce a colloidal gel containing over 99 per cent water. The superabsorbency and permeability of naturally occurring and synthetic hydrogels give this class of materials an amazing array of uses. These uses range from wound dressings and skin grafts to oxygen-permeable contact lenses to biodegradable delivery systems for drugs or pesticides and scaffolds for tissue engineering and regenerative medicine. Biomedical Applications of Hydrogels Handbook provides a comprehensive description of this diverse class of materials, covering both synthesis and properties and a broad range of research and commercial applications. The Handbook is divided into four sections: Stimuli-Sensitive Hydrogels, Hydrogels for Drug Delivery, Hydrogels for Tissue Engineering, and Hydrogels with Unique Properties. Key Features: Provides comprehensive coverage of the basic science and applications of a diverse class of materials Includes both naturally occurring and synthetic hydrogels Edited and written by world leaders in the field.
Author |
: Umile Gianfranco Spizzirri |
Publisher |
: CRC Press |
Total Pages |
: 362 |
Release |
: 2017-08-10 |
ISBN-10 |
: 9781498749022 |
ISBN-13 |
: 149874902X |
Rating |
: 4/5 (22 Downloads) |
Synopsis Functional Hydrogels in Drug Delivery by : Umile Gianfranco Spizzirri
The book deals with the synthesis and characterization of hydrogels specifically used as drug delivery systems. Each chapter includes the most recent updates about the different starting materials employed and the improvement of their physicochemical and biological properties to synthetize high performing carriers for specific uses.
Author |
: |
Publisher |
: |
Total Pages |
: |
Release |
: |
ISBN-10 |
: OCLC:1051941458 |
ISBN-13 |
: |
Rating |
: 4/5 (58 Downloads) |
Synopsis Photo-cross-linked Biodegradable Hydrogels Based on N-arm-poly(ethylene Glycol), Poly(ε-caprolactone) And/or Methacrylic Acid for Controlled Drug Release by :
In this paper, a novel kind of photo-cross-linked biodegradable hydrogels based on n-arm-poly(ethylene glycol) (n = 2, 3, and 4) and poly(ɛ-caprolactone) was prepared by ultraviolet-initiated free radical polymerization. The resulting n-arm-poly(ethylene glycol)-poly(ɛ-caprolactone) and n-arm-poly(ethylene glycol)-poly(ɛ-caprolactone) acrylate (n-arm-PEG-PCL-AC, macromer) were characterized by proton nuclear magnetic resonance and fourier transform infrared spectra. The influences of arm numbers and concentration of macromer on the properties of hydrogel were researched systematically, and the results showed that the gelation time, equilibrium swelling ratio, in vitro degradation, and drug release rate decreased with the increase of arm numbers and concentration of macromer. The degradation and drug release rate could be controlled by varying the cross-linking density of hydrogel, indicating a potential application as controlled drug delivery system. Cytotoxicity test of hydrogel extracts was conducted using L929 mouse fibroblasts, and the relative growth rate exceeded 75% (cytotoxicity type: class 1) after incubation for 24 h, showing excellent cytocompatibility. In addition, the paper presented a pH-sensitive hydrogel (G4pH) based on 4-arm-PEG-PCL-AC and acrylic acid, and the influences of pH value on swelling behaviors and in vitro drug release of the pH-sensitive hydrogel were examined. The hydrogels shrank under acidic condition and would swell in neutral or basic medium. The pH-dependent drug release behaviors indicated a promising application of the materials as oral drug delivery vehicles.
Author |
: Xian Jun Loh |
Publisher |
: Royal Society of Chemistry |
Total Pages |
: 198 |
Release |
: 2018-09-27 |
ISBN-10 |
: 9781782629405 |
ISBN-13 |
: 1782629408 |
Rating |
: 4/5 (05 Downloads) |
Synopsis Biodegradable Thermogels by : Xian Jun Loh
Biodegradable thermogels are a promising class of stimuli-responsive polymers. This book summarizes recent developments in thermogel research with a focus on synthesis and self-assembly mechanisms, gel biodegradability, and applications for drug delivery, cell encapsulation and tissue engineering. A closing chapter on commercialisation shows the challenges faced bringing this new material to market. Edited by leading authorities on the subject, this book offers a comprehensive overview for academics and professionals across polymer science, materials science and biomedical and chemical engineering.
Author |
: Rolando Barbucci |
Publisher |
: Springer Science & Business Media |
Total Pages |
: 201 |
Release |
: 2010-07-23 |
ISBN-10 |
: 9788847011045 |
ISBN-13 |
: 8847011043 |
Rating |
: 4/5 (45 Downloads) |
Synopsis Hydrogels by : Rolando Barbucci
The studies on Biohydrogels have had a rapid, exponential evolution in the last decades. This book is the result of an International conference gathering the most recent results in this field.
Author |
: Kai Guo |
Publisher |
: |
Total Pages |
: 324 |
Release |
: 2005 |
ISBN-10 |
: CORNELL:31924102824301 |
ISBN-13 |
: |
Rating |
: 4/5 (01 Downloads) |
Synopsis Biodegradable Unsaturated Poly(ester-amide)s and Their Hydrogels by : Kai Guo
Author |
: Young Kweon Choi |
Publisher |
: |
Total Pages |
: 458 |
Release |
: 1996 |
ISBN-10 |
: OCLC:34953609 |
ISBN-13 |
: |
Rating |
: 4/5 (09 Downloads) |
Synopsis Biodegradable Star-shaped Block Copolymer Hydrogels for Drug Delivery by : Young Kweon Choi