In response to the explosion of research in developmental neurobiology, this new edition of the Atlas of the Developing Rat Brain has been expanded to include all of the plates and diagrams of the previous book, PLUS an additional 95 plates and 95 diagrams delineating the entire rat nervous system. Atlas of the Developing Rat Nervous System features large, high-magnification photographs of serial brain sections of the embryonic and neonatal laboratory rat, with opposing fully labeled diagrams. Complementing the classic atlas by Paxinos and Watson, The Rat Brain in Stereotaxic Coordinates, Second Edition (Academic Press, 1986), this new atlas is the standard reference for developmental neuroscientists. Key Features * Provides section-by-section photographs and accompanying labeled diagrams of the embryonic and neonatal rat brain * Shows brain development at Embryonic Days 14 (Whole embryo), 16, 17, and 19, as well as Postnatal Day 0 * Delineates nerves, ganglia, arteries, veins, bones, and foramina of the head on Embryonic Days 14 and 19 * Depicts 912 brain structures or their primordial counterparts * Large size in an easy-to-use, spiral-bound format * Includes a full list of abbreviations, index of structures, and references * 224 photographs alongside meticulously drawn diagrams depict the central and peripheral nervous system and other body organs * Depicts ages E14, E16, and E19 in the customary coronal and sagittal planes and E17 and P0 in the coronal plane

The previous editions of The Rat Nervous System were indispensable guides for those working on the rat and mouse as experimental models. The fourth edition enhances this tradition, providing the latest information in the very active field of research on the brain, spinal cord, and peripheral nervous system. The structure, connections, and function are explained in exquisite detail, making this an essential book for any graduate student or scientist working on the rat or mouse nervous system. - Completely revised and updated content throughout, with entirely new chapters added - Beautifully illustrated so that even difficult concepts are rendered comprehensible - Provides a fundamental analysis of the anatomy of all areas of the central and peripheral nervous systems, as well as an introduction to their functions - Appeals to researchers working on other species, including humans

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This atlas provides an accurate and detailed depiction of all brain structures at fetal stage E17.5, Day of birth, and Day 6 postnatal. In addition to brain structures, the atlas delineates peripheral nerves, ganglia, arteries, veins, muscles bones and other organs. It is an indispensable guide for the interpretation of nervous system changes in gene knockout and transgenic mice. Contains: 43 photographs and drawings of Nissl-stained coronal sections of the brain of a fetal mouse at E17.5 days, 65 photographs and drawings of Nissl-stained coronal sections of the brain of a mouse on the day of birth, and 73 photographs and drawings of Nissl-stained coronal sections of the brain of a mouse aged 6 days postnatal. The drawings are based on the study of sections stained with Nissl and a range of neuroactive substances. In addition to brain structures, the atlas delineates peripheral nerves, ganglia, arteries, veins, muscles bones and other organs.

The result of 3 decades of original research and instruction by internationally referenced authors, Drs. Joseph Altman and Shirley A. Bayer, the Atlas of Prenatal Rat Brain Development provides a complete, state-of-the-art presentation of the developing prenatal rat brain. With the aid of advanced computer graphics, Altman and Bayer revolutionize the study of the highly vulnerable prenatal brain and bring us closer to understanding the dynamics of its development, its malfunctions, deficits, and abnormalities. Their contributions to the field of brain research, and hence to our knowledge of brain disorders, are unsurpassed. The Atlas contains more than 265 platesÛeach plate accompanied by a computer-aided drawing, a 3-dimensional reconstruction of brain slices never before achieved with such accuracy and clarity, that assists in the visualization of the brain and of the relationships among various brain regions. A new, user-friendly alphanumeric coding system is used, allowing for easy identification of brain regions.

The publication of the fifth volume completes this historic series of atlases. Available for the first time as a set, this award winning series provides the only complete record of the development of the human central nervous system from spinal cord gestation through the third trimester. The contents of the atlases are organized by coronal, sagittal, and horizontal planes of sectioning to ensure that nearly every structure in the developing brain is represented pictorially. Each volume provides two page spreads containing high resolution black and white images on one side and ghost images on the other with unabbreviated labels to apprise readers of the exact structures identified. The final volume provides a concluding essay that summarizes major events of CNS development, while offering a theoretical account of the morphogenetic processes involved. For more details, readers can access information specific to each volume: Vol. 1: Cat. No. 1420 The Spinal Cord from Gestational Week 4 to the 4th Postnatal Month Vol. 2: Cat. No. 1421 The Human Brain During the Second Trimester Vol. 3: Cat. No. 1422 The Human Brain During the Third Trimester Vol. 4: Cat. No. 1423 The Human Brain During the Late First Trimester Vol. 5: Cat. No. 1424 The Human Brain During the Early First Trimester From the 1960s through the 1980s, the work of legendary pioneers, Shirley Bayer and Joseph Altman chronicled the development of the rat nervous system. In the 1990s, they shifted their attention to humans when they realized how little was known about the development of the human central nervous system. Many disorders resulting from abnormal neural deficits could be better understood if normal development was itself better known. Bayer and Altman decided to apply their knowledge of rat nervous system development to humans by directly examining histological sections of normal human specimens. Funding their own work, they took over 10,000 photographs of the best preserved specimens available. Each of the photos was then scanned to create digitalized files that could be further examined with sophisticated equipment, including 3- dimensional reconstruction software. This set of atlases is the result of this effort. "We embarked on this ambitious project for two reasons. First, to fill a gaping void in the literature. ...Second, we hoped that by extrapolating from the experimental data obtained in animals, we could go beyond a mere narrative account of developmental landmarks in human CNS development to a dynamic analysis of some of the morphogenetic processes involved. What we were surprised to find is that our detailed examination of the full course of CNS development in normal human embryos and fetuses has come to shed new light on some of the basic mechanisms involved in the production, migration, differentiation, and assembly of CNS neurons...." This information is included in an extended monograph in Volume 5 that will no doubt serve as a launching pad for future research. Altman and Bayer, working for three decades at Purdue and Indiana Universities, revolutionized the research methods and pioneered the results that are available today.

The core of this book is an atlas of the rat brain viewed from 73 representative transverse levels along its longitudinal axis. New to this edition is a second drawing of gray and white matter distribution that illustrates major features of gray matter regionalizion in a color-coded way that is carried through the flatmaps of the rat CNS and the hierarchical nomenclature tables. Computer graphics files of the atlas and flatmaps are provided on the CD-ROM. They can be used to learn more about the structure of the brain, to map experimental results on standard or reference templates, to form databases of spatial information about the rat brain, and to create 3-D models.