Comprehensive Medicinal Chemistry III, Eight Volume Set provides a contemporary and forward-looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery. Reviews the strategies, technologies, principles, and applications of modern medicinal chemistry Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs

The Qualified Success And General Appeal Of Medicinal Chemistry Is Not Only Confined To The Indian Subcontinent, But It Has Also Won An Overwhelming Popularity In Other Parts Of The World. Specific Care Has Been Taken To Maintain And Sustain The Fundamental Philosophy Of The Textbook Embracing Rigidly The Original Pattern And Style Of Presentation With A Particular Expatiated Treatment Of Synthesis Of Potential Medicinal Compounds For The Ultimate Benefits Of The Teachers And The Taught Alike.The Present Thoroughly Revised And Skilfully Expanded Fourth Edition Essentially Contains Three New And Important Chapters, Namely : Molecular Modeling And Drug Design (Chapter 3), Adrenocortical Steroids (Chapter 24), And Antimycobacterial Agents (Chapter 26) So As To Make The Textbook More Useful To Its Readers.With The Advent Of Thirty Chapters The Present Updated Form Of Medicinal Chemistry Will Prove To Be An Asset For M. Pharm./B. Pharm. Degree Students, M. Sc. Pharmaceutical Chemistry, M.Sc. Applied Chemistry And M. Sc. Industrial Chemistry Throughout The Indian Universities.Medicinal Chemistry Appears As A Newly Designed And Artistically Presented In A Two-Colour Scheme So As To Facilitate A Distinctly More Effective Use Of The Book.This Highly Readable, Lucid, Handy, And Exceptionally Knowledgeable Textbook Will Definitely Win A Better, Bigger, And Confident Place For Itself Amongst Its Valued Readers.

This penetrating case study of institution building and entrepreneurship in science shows how a minor medical speciality evolved into a large and powerful academic discipline. Drawing extensively on little-used archival sources, the author analyses in detail how biomedical science became a central part of medical training and practice. The book shows how biochemistry was defined as a distinct discipline by the programmatic vision of individual biochemists and of patrons and competitors in related disciplines. It shows how discipline builders used research programmes as strategies that they adapted to the opportunities offered by changing educational markets and national medical reform movements in the United States, Britain and Germany. The author argues that the priorities and styles of various departments and schools of biochemistry reflect systematic social relationships between that discipline and biology, chemistry and medicine. Science is shaped by its service roles in particular local contexts: This is the central theme. The author's view of the political economy of modern science will be of interest to historians and social scientists, scientific and medical practitioners, and anyone interested in the ecology of knowledge in scientific institutions and professions.

Biomedical Chemistry provides readers with an understanding of how fundamental chemical concepts are used to combat some diseases. The authors explain the interdisciplinary relationship of chemistry with biology, physics, pharmacy and medicine. The results of chemical research can be applied to understand chemical processes in cells and in the body, and new methods for drug transportation. Also, basic chemical ideas and determination of disease etiology are approached by developing techniques to ensure optimum interaction between drugs and human cells. This Book is an excellent resource for students and researchers in health-related fields with frontier topics in medicinal and pharmaceutical chemistry, organic chemistry and biochemistry.

Deals with radiation processing as a whole using a chemical perspective. Offers basic information on the procedures taking place and covers radiation dosimetry plus a wide range of actual and potential applications. Provides excellent coverage of radiation processing literature with bibliographies pertaining to key areas of radiation chemistry.

A to Z of Chemists, Updated Edition tells the stories of nearly 100 chemists—both well-known scientific greats of history and contemporary scientists whose work is just verging on greatness. Readers will find fascinating entries on people such as Gertrude Belle Elion, who developed drugs to cure diseases as diverse as leukemia, gout, herpes, malaria, and arthritis. From famous mainstream chemists to minority scientists often excluded from similar titles, A to Z of Chemists, Updated Edition spans all cultures, ethnicities, and eras. Designed for high school through early college students, this title in the Notable Scientists series is also an ideal resource for all readers interested in chemistry. Articulated in everyday language, even the most complex concepts are accessible. While the majority of the scientists in this work are, first and foremost, chemists, there is a handful of physicists, biologists, and other scientists who made significant contributions to chemistry. People covered include: Robert Wilhelm Bunsen (1811–1899) Louis Pasteur (1822–1895) George Washington Carver (1864–1943) St. Elmo Brady (1884–1966) Karl Ziegler (1898–1973) Percy Lavon Julian (1899–1975) Linus Carl Pauling (1901–1994) Dorothy Crowfoot Hodgkin (1910–1994) Robert Burns Woodward (1917–1979) Sir George Porter (1920–2002) Sir Aaron Klug (1926–2018) Jean-Pierre Sauvage (1944–present) Aziz Sancar (1946–present) Ahmed Zewail (1946–2016) Venkatraman Ramakrishnan (1952–present)