This first volume provides a comprehensive overview on evolutionary, environmental and systematic aspects of antifreeze proteins. It shortly explains the physical properties of ice and further intelligibly describes the biology of the antifreeze proteins in different organisms, and offers a detailed insight into their history of evolution. In addition the book discusses the status of the current knowledge and ongoing research and highlights also those parts, where further investigation needs to be done. Together with the second volume on the biochemistry and molecular biology of antifreeze proteins, this book represents a unique, comprehensive work and a must-have for students and scientists in biochemistry, evolution, physiology and physical chemistry.

This second volume, written in four parts, offers the reader a thorough review on molecular, structural and applied aspects of antifreeze proteins. The first part treats the structure-function relationship and the physicochemical properties of antifreeze proteins; the second part provides insight into molecular mechanisms affected by antifreeze proteins; the third part presents some of the potential applications in various professional sectors and in the last part the book content is summarized and future research directions and ideas are discussed. Together with the first volume on the environment, systematic and evolution of antifreeze proteins, this book represents a unique, comprehensive work and a must-have for students and scientists in biochemistry, molecular biology, biotechnology and physical chemistry.

A collection of works by researchers who have studied the antifreeze proteins which enable organisms to avoid freezing under extreme conditions.

Antifreeze proteins, also known as thermal hysteresis proteins, ice binding proteins and ice structuring proteins, prevent the growth of ice crystals in several cold blooded organisms. First discovered in fish, they have also been found in insects, plants, fungi and bacteria. Antifreeze proteins cause the non-colligative depression of the freezing point of water, a property which has been exploited in the practical applications of antifreeze proteins such as improving the texture of ice cream, and could be used to extend the crop growing season or allow fish to thrive in cold waters. This book provides clear information on what is known about antifreeze proteins today and how to study them.

How to synthesize native and modified proteins in the test tube With contributions from a panel of experts representing a range of disciplines, Total Chemical Synthesis of Proteins presents a carefully curated collection of synthetic approaches and strategies for the total synthesis of native and modified proteins. Comprehensive in scope, this important reference explores the three main chemoselective ligation methods for assembling unprotected peptide segments, including native chemical ligation (NCL). It includes information on synthetic strategies for the complex polypeptides that constitute glycoproteins, sulfoproteins, and membrane proteins, as well as their characterization. In addition, important areas of application for total protein synthesis are detailed, such as protein crystallography, protein engineering, and biomedical research. The authors also discuss the synthetic challenges that remain to be addressed. This unmatched resource: Contains valuable insights from the pioneers in the field of chemical protein synthesis Presents proven synthetic approaches for a range of protein families Explores key applications of precisely controlled protein synthesis, including novel diagnostics and therapeutics Written for organic chemists, biochemists, biotechnologists, and molecular biologists, Total Chemical Synthesis of Proteins provides key knowledge for everyone venturing into the burgeoning field of protein design and synthetic biology.

This unique book presents ways to mitigate the disastrous effects of snow/ice accumulation and discusses the mechanisms of new coatings deicing technologies. The strategies currently used to combat ice accumulation problems involve chemical, mechanical or electrical approaches. These are expensive and labor intensive, and the use of chemicals raises serious environmental concerns. The availability of truly icephobic surfaces or coatings will be a big boon in preventing the devastating effects of ice accumulation. Currently, there is tremendous interest in harnessing nanotechnology in rendering surfaces icephobic or in devising icephobic surface materials and coatings, and all signals indicate that such interest will continue unabated in the future. As the key issue regarding icephobic materials or coatings is their durability, much effort is being spent in developing surface materials or coatings which can be effective over a long period. With the tremendous activity in this arena, there is strong hope that in the not too distant future, durable surface materials or coatings will come to fruition. This book contains 20 chapters by subject matter experts and is divided into three parts— Part 1: Fundamentals of Ice Formation and Characterization; Part 2: Ice Adhesion and Its Measurement; and Part 3: Methods to Mitigate Ice Adhesion. The topics covered include: factors influencing the formation, adhesion and friction of ice; ice nucleation on solid surfaces; physics of ice nucleation and growth on a surface; condensation frosting; defrosting properties of structured surfaces; relationship between surface free energy and ice adhesion to surfaces; metrology of ice adhesion; test methods for quantifying ice adhesion strength to surfaces; interlaboratory studies of ice adhesion strength; mechanisms of surface icing and deicing technologies; icephobicities of superhydrophobic surfaces; anti-icing using microstructured surfaces; icephobic surfaces: features and challenges; bio-inspired anti-icing surface materials; durability of anti-icing coatings; durability of icephobic coatings; bio-inspired icephobic coatings; protection from ice accretion on aircraft; and numerical modeling and its application to inflight icing.

When you're cooking, you're a chemist! Every time you follow or modify a recipe, you are experimenting with acids and bases, emulsions and suspensions, gels and foams. In your kitchen you denature proteins, crystallize compounds, react enzymes with substrates, and nurture desired microbial life while suppressing harmful bacteria and fungi. And unlike in a laboratory, you can eat your experiments to verify your hypotheses. In Culinary Reactions, author Simon Quellen Field turns measuring cups, stovetop burners, and mixing bowls into graduated cylinders, Bunsen burners, and beakers. How does altering the ratio of flour, sugar, yeast, salt, butter, and water affect how high bread rises? Why is whipped cream made with nitrous oxide rather than the more common carbon dioxide? And why does Hollandaise sauce call for “clarified” butter? This easy-to-follow primer even includes recipes to demonstrate the concepts being discussed, including: &· Whipped Creamsicle Topping—a foam &· Cherry Dream Cheese—a protein gel &· Lemonade with Chameleon Eggs—an acid indicator

Studies on transgenic fish, in contrast to mammals, are still in their infancy. However, it is evident that such fish will not only be of considerable economic benefit to aquaculture but will enable scientists to make quantum leaps in their understanding of the physiological and biochemical mechanisms unique to fish, and of the developmental biology of vertebrates in general.The potential of transgenic fish for research and industrial development is beginning to be widely recognized. This timely volume encompasses the full spectrum of current research on transgenic fish. It will be valuable to many scientists who intend to explore the merits of the technology for the first time.

The study of insects at low temperature is a comparatively new field. Only recently has insect cryobiology begun to mature, as research moves from a descriptive approach to a search for underlying mechanisms at diverse levels of organization ranging from the gene and cell to ecological and evolutionary relationships. Knowledge of insect responses to low temperature is crucial for understanding the biology of insects living in seasonally varying habitats as well as in polar regions. It is not possible to precisely define low temperature. In the tropics exposure to 10-15°C may induce chill coma or death, whereas some insects in temperate and polar regions remain active and indeed even able to fly at O°C or below. In contrast, for persons interested in cryopreservation, low temperature may mean storage in liquid nitrogen at - 196°C. In the last decade, interest in adaptations of invertebrates to low temperature has risen steadily. In part, this book had its origins in a symposium on this subject that was held at the annual meeting of the Entomological Society of America in Louisville, Kentucky, USA in December, 1988. However, the emergence and growth of this area has also been strongly influenced by an informal group of investigators who met in a series of symposia held in Oslo, Norway in 1982, in Victoria, British Columbia, Canada in 1985 and in Cambridge, England in 1988. Another is scheduled for Binghamton, New York, USA (1990).