The new edition of this highly successful annual pocket guide presents clinicians with the most recent information in the field of antimicrobial therapy and infectious diseases. Written by recognised experts in infectious disease, this edition discusses serum and urinary spectrum summaries of antibiotics and clinically relevant pharmacokinetics. The sixteenth edition has been fully updated to provide clinicians with the latest advances in their field. Unique features of the book include clinical synopses of common and uncommon infections worldwide, differential diagnosis of infectious diseases and non-infectious mimics, antibiotic IV-to-PO switch therapy options for infectious diseases; and HIV, HCV, Peds ID, antibiotic prophylaxis and immunisations, chest film differential diagnosis atlas, and gram stain atlas. Key Points Sixteenth edition presenting most recent information in field of antimicrobial therapy and infectious disease Highly successful annual pocket guide Includes many new topics Authored by leading experts in the field Includes free access to the app

Antibiotic Basics for Clinicians, South Asian Edition, simplifies the antibiotic selection process for the clinicians with up-to-date information on the latest and most clinically relevant antibacterial medications. This time-saving resource helps medical students master the rationale behind antibiotic selection for common

Virtually everyone has taken antibiotics. They can be lifesavers -- and they can be useless. What are they? How are they used? And what happens as the effectiveness of antibiotics continues to decline? Antibiotics: What Everyone Needs to Know(R) examines the personal and societal implications of our planet's most important -- and frequently misused -- medications. In a question-and-answer format, it unpacks the most complicated aspects of this issue, including: How antibiotics are used (and overused) in humans, plants, and livestock; the causes and consequences of bacterial resistance to antibiotics; how the globalized world enables antibiotic resistance to spread quickly; and the difficult decisions ahead for both medical care and the food system. Grounded in the latest scientific research and crafted for general readers, Antibiotics: What Everyone Needs to Know(R) offers a clear-eyed overview of where we are, and what the future holds, as antibiotics lose their power.

Spectrum of activity --

Kucers’ The Use of Antibiotics is the definitive, internationally-authored reference, providing everything that the infectious diseases specialist and prescriber needs to know about antimicrobials in this vast and rapidly developing field. The much-expanded Seventh Edition comprises 4800 pages in 3 volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into four sections - antibiotics, anti-fungal drugs, anti-parasitic drugs, and anti-viral drugs - and is highly structured for ease of reference. Each chapter is organized in a consistent format, covering susceptibility, formulations and dosing (adult and pediatric), pharmacokinetics and pharmacodynamics, toxicity, and drug distribution, with detailed discussion regarding clinical uses - a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with expert contributors representing Europe, Africa, Asia, Australia, South America, the US, and Canada, the Seventh Edition adopts a truly global approach. It remains invaluable for anyone using antimicrobial agents in their clinical practice and provides, in a systematic and concise manner, all the information required when prescribing an antimicrobial to treat infection.

This report presents the recommendations of the WHO Expert Committee responsible for updating the WHO Model List of Essential Medicines. The first part contains a progress report on the new procedures for updating the Model List and the development of the WHO Essential Medicines Library. It continues with a section on changes made in revising the Model List followed by a review of some sections such as hypertensive medicines and fast track procedures for deleting items. Annexes include the 13th version of the Model List and items on the list sorted according to their 5-level Anatomical Therapeutic Chemical classification codes.

The new edition of this highly successful annual pocket guide presents clinicians with the most recent information in the field of antimicrobial therapy and infectious diseases. Written by recognised experts in infectious disease, this edition discusses serum and urinary spectrum summaries of antibiotics and clinically relevant pharmacokinetics. The seventeenth edition has been fully updated to provide clinicians with the latest advances in their field. Unique features of the book include clinical synopses of common and uncommon infections worldwide, differential diagnosis of infectious diseases and non-infectious mimics, antibiotic IV-to-PO switch therapy options for infectious diseases; and HIV, HCV, Peds ID, antibiotic prophylaxis and immunisations, chest film differential diagnosis atlas, and gram stain atlas. Key Points Seventeenth edition presenting most recent information in field of antimicrobial therapy and infectious disease Highly successful annual pocket guide Includes many new topics and updates on new drugs Authored by leading experts in the field Includes free access to the app

The 19th edition of the EMRA Antibiotic Guide provides clear interpretation of the most recent IDSA guidelines for treating pneumonia, plus an overview of antibiotic use in pregnancy, and more. You can’t go on shift without this incredible resource – and you won’t want to. Navigate the multitude of choices in antibiotics quickly and efficiently so you can offer your patients the best care based on the latest guidelines. Protect against overprescribing, address pediatric dosage questions, examine penicillin usage, and stay up-to-date on new approvals and guidance from the FDA.

It is our wish that readers discover the importance of polymyxin structure in relation to the mechanisms of activity, resistance and toxicity. We emphasized that reliable analytic methods for polymyxins are critical when investigating their pharmacokinetics (PK) and pharmacodynamics (PD). The complicated dose definitions and different pharmacopoeial standards have already compromised the safe use of polymyxins in patients. Therefore, informed by the latest pharmacological information, scientifically-based dosing recommendations have been proposed for intravenous polymyxins. Considering the PK/PD limitations and potential development of resistance, polymyxin combinations are encouraged; however, the current literature has not shown definite microbiological benefits, possibly because most clinical studies to date overlooked key PK/PD principles. Nephrotoxicity is the major dose-limiting factor and it is imperative to elucidate the mechanisms and develop novel approaches to minimize polymyxin-associated toxicities. In addition, the anti-endotoxin effect of polymyxins supports their clinical use to treat Gram-negative sepsis. Fortunately, the discovery of new-generation polymyxins with wider therapeutic windows has benefited from the latest achievements in polymyxin research.