Vol. for 1906 includes the reports of the Commandant of U.S. Signal School and Staff College.

This work focuses primarily on military medicine during this conflict. Historian Vincent J. Cirillo argues that there is a universal element of military culture that stifles medical progress. This war gave army medical officers an opportunity to introduce to the battlefield new medical technology, including the X-ray, aseptic surgery and sanitary systems derived from the germ theory. With few exceptions, however, their recommendations were ignored almost completely.