Animal Toxins

Animal Toxins
Author :
Publisher :
Total Pages : 462
Release :
ISBN-10 : UOM:39015003211722
ISBN-13 :
Rating : 4/5 (22 Downloads)

Synopsis Animal Toxins by : Findlay E. Russell

Small Animal Toxicology

Small Animal Toxicology
Author :
Publisher : Elsevier Health Sciences
Total Pages : 955
Release :
ISBN-10 : 9780323241984
ISBN-13 : 0323241980
Rating : 4/5 (84 Downloads)

Synopsis Small Animal Toxicology by : Patricia A. Talcott

- 20 new chapters have been added - New topics include a list of toxicants affecting body systems, management of toxins in pregnancy, diagnostic toxicology, bacterial toxins, and cosmetic/toilet articles - Snake-bite injuries are treated in two separate, expanded chapters: Pit Vipers and Coral Snakes - Section on pharmaceuticals includes bromides, anticonvulsants, tricycle antidepressants, monoamine oxidize inhibitors, B-adrenergic toxicities, and vitamins A and D - Additional specific toxicants are covered, including Amitraz, hydramethylon, ethanol, mercury, toad toxins, poisonous frogs, salamanders, newts and venomous arthropods•Additional specific toxicants are covered, including Amitraz, hydramethylon, ethanol, mercury, toad toxins, poisonous frogs, salamanders, newts and venomous arthropods.

Animal Toxins

Animal Toxins
Author :
Publisher : Springer Science & Business Media
Total Pages : 394
Release :
ISBN-10 : 3764359838
ISBN-13 : 9783764359836
Rating : 4/5 (38 Downloads)

Synopsis Animal Toxins by : Hervé Rochat

Natural toxins form a major component of the molecular tools used increasingly frequently by the ever growing number of laboratories of various kinds. Evidence for this is provided not only by the increasing number of firms including such toxins in their catalogues but also by the large number of demands received by those who discover new toxins. Twenty chapters survey important aspects of toxin origin, their structure and molecular mechanism, and their cellular and pathogenic effects. In addition, the text provides comprehensive and specific methodology for the application of these toxins in the research laboratory. This begins with the description of the method of extraction, biochemical and pharmacological characterization, and assessment of purity, and continues with methods for chemical modification, e.g. labelling, and eventually describes applications in pharmacological studies in vivo and/or in vitro. The length of this book has been kept reasonable by concentrating on...

Animal Toxins

Animal Toxins
Author :
Publisher : Birkhäuser
Total Pages : 376
Release :
ISBN-10 : 9783034884662
ISBN-13 : 3034884664
Rating : 4/5 (62 Downloads)

Synopsis Animal Toxins by : Herve Rochat

This manual surveys toxins from insects, spiders, mollusks, fish, and snakes which have biotechnological applications. It reviews aspects of toxin origin, their molecular mechanism, and their cellular and pathogenic effects. It also provides methodology for the application of these toxins in the research laboratory. This includes a description of the extraction methods, biochemical characterization, and applications in pharmacological studies.

Venoms to Drugs

Venoms to Drugs
Author :
Publisher : Royal Society of Chemistry
Total Pages : 338
Release :
ISBN-10 : 9781849736633
ISBN-13 : 1849736634
Rating : 4/5 (33 Downloads)

Synopsis Venoms to Drugs by : Glenn King

This unique book will provide an up to date and comprehensive account of the potential of peptides and proteins from animal venoms as possible therapeutics. The pharmaceutical industry has become increasingly interested in biologics from animal venoms as a potential source for therapeutic agents in recent years, with a particularly emphasis on peptides. To date six drugs derived from venom peptides or proteins have been approved by the FDA, with nine further agents currently being investigated in clinical trials. In addition to these drugs in approved or advanced stages of development, many more peptides and proteins are being studied in varying stages of preclinical development. Topics covered include chemistry and structural biology of animal venoms, proteomic and transcriptomic approaches to drug discovery, bioassays, high-throughput screens and target identification, and reptile, scorpion, spider and cone snail venoms as a platform for drug development. Case studies are used to illustrate methods and successes and highlight issues surrounding administration and other important lessons that have been learnt from the development of approved therapeutics based on venoms. The first text to focus on this fascinating area and bridging an important gap, this book will provide the reader with essential and current knowledge on this fast-developing area. Venoms to Drugs will find wide readership with researchers working in academia and industry working in all medicinal and pharmaceutical areas.

Nature's Medicine Chest

Nature's Medicine Chest
Author :
Publisher : Reader's Digest Association
Total Pages : 168
Release :
ISBN-10 : 0762102616
ISBN-13 : 9780762102617
Rating : 4/5 (16 Downloads)

Synopsis Nature's Medicine Chest by :

This book introduces the reader to herbal medicine; how to prepare and use herbal remedies. Includes notes on dosage and preparation and application of the remedies.

Heart and Toxins

Heart and Toxins
Author :
Publisher : Elsevier
Total Pages : 668
Release :
ISBN-10 : 9780124165991
ISBN-13 : 0124165990
Rating : 4/5 (91 Downloads)

Synopsis Heart and Toxins by : Dr. Meenakshisundaram Sundaram Ramachandran

The Heart and Toxins brings together global experts to provide the latest information and clinical trials that make the connection between genetic susceptibility, gene expression, and environmental factors in cardiovascular diseases. This unique reference, edited by renowned cardiologist Meenakshi Sundaram Ramachandran, solves the problem of managing multiple clinical cases of cardiovascular toxicity. It allows connections to be made between research, diagnosis, and treatment to avoid higher morbidity and mortality rates as a result of cardiovascular toxicity. - Structured to bring together exploration into the epidemiology, molecular mechanism, pathogenesis, environmental factors and management in cardiovascular toxins - Included various topics on cardiovascular toxins such as plant, chemical, animal, nanomaterial and marine biology induced cardiac damage – which are new ideas discussed in detail - Comprehensive chapters on the cardiovascular toxicity from drugs, radiotherapy and radiological imaging - Enables you to manage multiple clinical cases of cardiovascular toxicity - Outlined conclusions at the end of each chapter providing "key learning points to help you organize the chapter's details without losing insight

Animal Toxins

Animal Toxins
Author :
Publisher : Elsevier
Total Pages : 445
Release :
ISBN-10 : 9781483186108
ISBN-13 : 1483186105
Rating : 4/5 (08 Downloads)

Synopsis Animal Toxins by : Findlay E. Russell

Animal Toxins is a collection of papers that tackles the advancement in studies that aim to enhance the contemporary understanding of animal toxins. The materials in the text are organized according to the organism they cover. The first section tackles the concerns with venomous arthropods, such as the structure of the venom gland of the black widow spider Latrodectus mactans and the biochemical-immunochemical aspects of the venom from the scorpion Centruroides sculpturatus. Next, articles about poisonous marine animals are presented, which include differentiation of the poisons of fish, shellfish, and plankton and block of sensory nerve conduction in the cat by mussel poison and tetrodotoxin. In Section III, the selection reviews papers about snakes and amphibians, such as epidemiological methods in studying venomous snakebites and chemistry of cytotoxic substances in amphibian toxins. The book will be of great interest to toxicologists, zoologists, and biochemists.

Intentional Human Dosing Studies for EPA Regulatory Purposes

Intentional Human Dosing Studies for EPA Regulatory Purposes
Author :
Publisher : National Academies Press
Total Pages : 226
Release :
ISBN-10 : 9780309166416
ISBN-13 : 0309166411
Rating : 4/5 (16 Downloads)

Synopsis Intentional Human Dosing Studies for EPA Regulatory Purposes by : National Research Council

The EPA commissioned The National Academies to provide advice on the vexing question of whether and, if so, under what circumstances EPA should accept and consider intentional human dosing studies conducted by companies or other sources outside the agency (so-called third parties) to gather evidence relating to the risks of a chemical or the conditions under which exposure to it could be judged safe. This report recommends that such studies be conducted and used for regulatory purposes only if all of several strict conditions are met, including the following: The study is necessary and scientifically valid, meaning that it addresses an important regulatory question that can't be answered with animal studies or nondosing human studies; The societal benefits of the study outweigh any anticipated risks to participants. At no time, even when benefits beyond improved regulation exist, can a human dosing study be justified that is anticipated to cause lasting harm to study participants; and All recognized ethical standards and procedures for protecting the interests of study participants are observed. In addition, EPA should establish a Human Studies Review Board (HSRB) to evaluate all human dosing studiesâ€"both at the beginning and upon completion of the experimentsâ€"if they are carried out with the intent of affecting the agency's policy-making.

Clostridial Diseases of Animals

Clostridial Diseases of Animals
Author :
Publisher : John Wiley & Sons
Total Pages : 356
Release :
ISBN-10 : 9781118728406
ISBN-13 : 1118728408
Rating : 4/5 (06 Downloads)

Synopsis Clostridial Diseases of Animals by : Francisco A. Uzal

Clostridial Diseases of Animals is the first book to focus on clostridial diseases in domestic and wild animals, offering a comprehensive reference on these common diseases. Provides a single resource for all aspects of clostridial diseases Presents current, comprehensive information with a focus on clinical relevance Covers each disease in depth, including etiology, epidemiology, clinics, gross pathology, histopathology, diagnostics, diagnostic criteria, prophylaxis, control, and treatment Written by the world-leading experts in the field of clostridial diseases in animals Offers photographs and summary tables to support the concepts discussed in the text and aid in recognition