Animal Cell Technology: From Target to Market

Animal Cell Technology: From Target to Market
Author :
Publisher : Springer Science & Business Media
Total Pages : 657
Release :
ISBN-10 : 9789401003698
ISBN-13 : 9401003696
Rating : 4/5 (98 Downloads)

Synopsis Animal Cell Technology: From Target to Market by : E. Lindner-Olsson

Proceedings of the 17th ESACT Meeting June 10-14, 2001, Tylösand, Sweden

Cell Culture Technology for Pharmaceutical and Cell-Based Therapies

Cell Culture Technology for Pharmaceutical and Cell-Based Therapies
Author :
Publisher : CRC Press
Total Pages : 788
Release :
ISBN-10 : 9780849351068
ISBN-13 : 0849351065
Rating : 4/5 (68 Downloads)

Synopsis Cell Culture Technology for Pharmaceutical and Cell-Based Therapies by : Sadettin Ozturk

Edited by two of the most distinguished pioneers in genetic manipulation and bioprocess technology, this bestselling reference presents a comprehensive overview of current cell culture technology used in the pharmaceutical industry. Contributions from several leading researchers showcase the importance of gene discovery and genomic technology devel

Protein Hydrolysates in Biotechnology

Protein Hydrolysates in Biotechnology
Author :
Publisher : Springer Science & Business Media
Total Pages : 237
Release :
ISBN-10 : 9781402066740
ISBN-13 : 1402066740
Rating : 4/5 (40 Downloads)

Synopsis Protein Hydrolysates in Biotechnology by : Vijai K. Pasupuleti

Protein hydrolysates, otherwise commonly known as peptones or peptides, are used in a wide variety of products in fermentation and biotechnology industries. The term “peptone” was first introduced in 1880 by Nagelli for growing bacterial cultures. However, later it was discovered that peptones derived from the partial digestion of proteins would furnish organic nitrogen in readily available form. Ever since, p- tones, which are commonly known as protein hydrolysates, have been used not only for growth of microbial cultures, but also as nitrogen source in commercial fermen- tions using animal cells and recombinant microorganisms for the production of value added products such as therapeutic proteins, hormones, vaccines, etc. Today, the characterization, screening and manufacturing of protein hyd- lysates has become more sophisticated, with the introduction of reliable analytical instrumentation, high throughput screening techniques coupled with statistical design approaches, novel enzymes and efficient downstream processing equipment. This has enabled the introduction of custom-built products for specialized appli- tions in diverse fields of fermentation and biotechnology, such as the following. 1. Protein hydrolysates are used as much more than a simple nitrogen source. For example, the productivities of several therapeutic drugs made by animal cells and recombinant microorganisms have been markedly increased by use of p- tein hydrolysates. This is extremely important when capacities are limited. 2. Protein hydrolysates are employed in the manufacturing of vaccines by ferm- tation processes and also used as vaccine stabilizers.

Advancing Science and Elimination of the Use of Laboratory Animals for the Development and Control of Vaccines and Hormones

Advancing Science and Elimination of the Use of Laboratory Animals for the Development and Control of Vaccines and Hormones
Author :
Publisher : S. Karger AG (Switzerland)
Total Pages : 360
Release :
ISBN-10 : UOM:39015056882437
ISBN-13 :
Rating : 4/5 (37 Downloads)

Synopsis Advancing Science and Elimination of the Use of Laboratory Animals for the Development and Control of Vaccines and Hormones by : Fred Brown

Animal experimentation plays a major role in the development and control of biological products and large numbers of animals are used for routine batch control. During the past few years considerable attention has been paid to the concept of replacing, reducing and refining (the three Rs) the use of animals for this purpose. This volume contains the proceedings of an international meeting held in Utrecht in November 2001 in which the problems associated with applying the three Rs were discussed. Particular emphasis was given to the validation and regulatory acceptance of in vitro methods and new concepts of quality control. Those issues are important for the scientific community at large as well as manufacturers, regulatory authorities and everyone concerned with animal welfare.

Animal Cell Technology Meets Genomics

Animal Cell Technology Meets Genomics
Author :
Publisher : Springer Science & Business Media
Total Pages : 920
Release :
ISBN-10 : 1402027915
ISBN-13 : 9781402027918
Rating : 4/5 (15 Downloads)

Synopsis Animal Cell Technology Meets Genomics by : Francesc Gòdia

The 18th ESACT meeting was celebrated in Granada (Spain) in May 2003, and was entitled "Animal Cell Technology Meets Genomics", in order to reflect that the emerging technologies in the area of genomics, proteomics and other "-omics"-type disciplines will provide key technological assets to increase knowledge and open new horizons in animal cell technology. During the meeting a variety of top-class emerging technologies were presented together with the lastest advances in more mature industrial areas. The meeting was opened by a first session devoted to the understanding of basic cellular mechanisms, and four sessions focused on applied aspects of animal cell technology: Cell-based therapies and gene-based therapies, target discovery and biopharmaceuticals. The Granada Meeting has also seen a special focus on forefront industrial case studies. The spirit and scientific excellence of the 18th ESACT meeting is now reflected in different chapters of the book. The book presents, in form of short papers, a high number of the contributions to the meeting, and has been prepared with the aim to provide a relevant reference of the current research efforts in Animal Cell Technology.

Animal Cell Technology: Basic & Applied Aspects

Animal Cell Technology: Basic & Applied Aspects
Author :
Publisher : Springer Science & Business Media
Total Pages : 354
Release :
ISBN-10 : 9780306468650
ISBN-13 : 0306468654
Rating : 4/5 (50 Downloads)

Synopsis Animal Cell Technology: Basic & Applied Aspects by : Y. Kitagawa

Animal cell technology is a growing discipline of cell biology which aims not only to understand structures, functions and behaviors of differentiated animal cells but also to ascertain their abilities to be used for industrial and medical purposes. The goal of animal cell technology includes accomplishments of clonal expansion of differentiated cells with useful ability, optimization of their culture conditions, modulation of their ability for production of medically and pharmaceutically important proteins, and the application of animal cells to gene therapy and artificial organs. This Volume gives the readers a complete review of the present state of the art in Japan. The Proceedings will be useful for cell biologists, biochemists, molecular biologists, immunologists, biochemical engineers and other disciplines related to animal cell culture, working either in academic environments or in industries of biotechnology and pharmacy.

Animal Cell Technology: From Target to Market

Animal Cell Technology: From Target to Market
Author :
Publisher : Springer Science & Business Media
Total Pages : 684
Release :
ISBN-10 : 1402002645
ISBN-13 : 9781402002649
Rating : 4/5 (45 Downloads)

Synopsis Animal Cell Technology: From Target to Market by : European Society of Animal Cell Technology. General Meeting

This book is the lasting product, a resource of up-to-date information in the scientific literature for the field of animal cell technology, as it was presented during a pleasant and stimulating meeting in Tylösand, Sweden, in June 2001. The title of the meeting, From Target to Market, indicates the usefulness of Animal Cell Technology during all steps in the pharmaceutical development process. Following the biotech products reaching the market, it shows an upward trend in the contribution of biotech products to total New Molecular Entity output in the nineties, which continued until 1996 when biotech represented 25% of the annual output. Since then the proportion has been decreasing. A perceived hurdle from a market perspective is that a protein per definition is biodegradable and thus requires intravenous, or for some drugs subcutaneous administration. New promising administration technologies such as pulmonary delivery were highlighted at this meeting. The emphasis on project selection prior to entry in the development phase has triggered a portfolio management using more extensive preclinical data before a development decision is taken. Animal cells have become a very important tool in the drug discovery process. The next generation of products will evolve from applications such as gene therapy, novel vaccines, cell therapy, and gene regulation. Animal cell technology has a major role to play in the post-sequence era.

Memorias do Instituto Butantan

Memorias do Instituto Butantan
Author :
Publisher :
Total Pages : 438
Release :
ISBN-10 : UCLA:L0090484445
ISBN-13 :
Rating : 4/5 (45 Downloads)

Synopsis Memorias do Instituto Butantan by : Instituto Butantan

Kirk-Othmer Encyclopedia of Chemical Technology, Volume 5

Kirk-Othmer Encyclopedia of Chemical Technology, Volume 5
Author :
Publisher : Wiley-Interscience
Total Pages : 906
Release :
ISBN-10 : 0471485187
ISBN-13 : 9780471485186
Rating : 4/5 (87 Downloads)

Synopsis Kirk-Othmer Encyclopedia of Chemical Technology, Volume 5 by : Kirk-Othmer

The fifth edition of the Kirk-Othmer Encyclopedia of Chemical Technology builds upon the solid foundation of the previous editions, which have proven to be a mainstay for chemists, biochemists, and engineers at academic, industrial, and government institutions since publication of the first edition in 1949. The new edition includes necessary adjustments and modernisation of the content to reflect changes and developments in chemical technology. Presenting a wide scope of articles on chemical substances, properties, manufacturing, and uses; on industrial processes, unit operations in chemical engineering; and on fundamentals and scientific subjects related to the field. The Encyclopedia describes established technology along with cutting edge topics of interest in the wide field of chemical technology, whilst uniquely providing the necessary perspective and insight into pertinent aspects, rather than merely presenting information. * Set begins publication in March 2004 * Over 1000 articles in 27 volumes * More than 600 new or updated articles Reviews from the previous edition: "The most indispensable reference in the English language on all aspects of chemical technology...the best reference of its kind". Chemical Engineering News, 1992 "Overall, ECT is well written and cleanly edited, and no library claiming to be a useful resource for chemical engineering professionals should be without it." Nicholas Basta, Chemical Engineering, December 1992

BioNMR in Drug Research

BioNMR in Drug Research
Author :
Publisher : Wiley-VCH
Total Pages : 520
Release :
ISBN-10 : UOM:39015056674222
ISBN-13 :
Rating : 4/5 (22 Downloads)

Synopsis BioNMR in Drug Research by : Oliver Zerbe

The vast progress made in the investigation of biomolecules using NMR has only recently been rewarded with the Nobel Prize for Kurt Wüthrich. Edited by a former coworker of Wüthrich, this book presents the theoretical background on NMR of biomolecules, plus the use of NMR techniques in determining the structures of proteins and nucleic acids. BioNMR spectroscopy offers a universal tool for examining the binding of an active substance to its target protein. Its use thereby benefits the rational development of drugs. This interaction can now be investigated in a hitherto unparalleled precision and displayed in 3D - an important prerequisite for the targeted development of new active substances. The latest methods for characterizing substance-receptor complexes are demonstrated backed by many case studies from pharmaceutical research. Thus it comes as no surprise that a large number of the authors are working for leading pharmaceutical companies. With its successful mixture of basic information and application strategies, coupled with many real-life examples, this is an invaluable guide for both NMR spectroscopists and pharmaceutical researchers.