An Introduction To Pharmaceutical Formulation
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Author |
: A. G. Fishburn |
Publisher |
: Elsevier |
Total Pages |
: 201 |
Release |
: 2013-10-22 |
ISBN-10 |
: 9781483138534 |
ISBN-13 |
: 1483138534 |
Rating |
: 4/5 (34 Downloads) |
Synopsis An Introduction to Pharmaceutical Formulation by : A. G. Fishburn
An Introduction to Pharmaceutical Formulation describes the various forms in which drugs may be supplied to doctors, patients, and veterinary surgeons. An account is given of the materials which may be added to drugs in order to provide formulated products, and of the methods by which formulations are assessed. The book begins with a background on pharmaceutical formulation, describing manufactured and official formulations, important criteria for a formulation, and technical advances in pharmacy during the post-war period. This is followed by separate chapters on diluents, solvents, and liquid vehicles; thickeners and binders; the chemistry and pharmacology of surface-active agents; and colors, flavors, and preservatives. Subsequent chapters cover solid, liquid, and paste formulations; controlled drug release; the stability of formulations; the importance of the container of the formulation; and large-scale manufacturing of formulated products. This book is intended primarily for students of pharmacy. It is not a textbook of practical or theoretical pharmaceutics but should be read in conjunction with other books on these subjects.
Author |
: Geoffrey D Tovey |
Publisher |
: Royal Society of Chemistry |
Total Pages |
: 432 |
Release |
: 2018-06-25 |
ISBN-10 |
: 9781849739412 |
ISBN-13 |
: 1849739412 |
Rating |
: 4/5 (12 Downloads) |
Synopsis Pharmaceutical Formulation by : Geoffrey D Tovey
Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety and stability of the final medicinal product. Modern formulation science deals with biologics as well as small molecules. Regulatory and quality demands, in addition to advances in processing technologies, result in growing challenges as well as possibilities for the field. Pharmaceutical Formulation provides an up to date source of information for all who wish to understand the principles and practice of formulation in the drug industry. The book provides an understanding of the links between formulation theory and the practicalities of processing in a commercial environment, giving researchers the knowledge to produce effective pharmaceutical products that can be approved and manufactured. The first chapters introduce readers to different dosage forms, including oral liquid products, topical products and solid dosage forms such as tablets and capsules. Subsequent chapters cover pharmaceutical coatings, controlled release drug delivery and dosage forms designed specifically for paediatric and geriatric patients. The final chapter provides an introduction to the vital role intellectual property plays in drug development. Covering modern processing methods and recent changes in the regulatory and quality demands of the industry, Pharmaceutical Formulation is an essential, up to date resource for students and researchers working in academia and in the pharmaceutical industry.
Author |
: Jiben Roy |
Publisher |
: Elsevier |
Total Pages |
: 449 |
Release |
: 2011-07-25 |
ISBN-10 |
: 9781908818041 |
ISBN-13 |
: 1908818042 |
Rating |
: 4/5 (41 Downloads) |
Synopsis An Introduction to Pharmaceutical Sciences by : Jiben Roy
This textbook is written as a unified approach to various topics, ranging from drug discovery to manufacturing, techniques and technology, regulation and marketing. The key theme of the book is pharmaceuticals - what every student of pharmaceutical sciences should know: from the active pharmaceutical ingredients to the preparation of various dosage forms along with the relevant chemistry, this book makes pharmaceuticals relevant to undergraduate students of pharmacy and pharmaceutical sciences.This book explains how a particular drug was discovered and then converted from lab-scale to manufacturing scale, to the market. It explains the motivation for drug discovery, the reaction chemistry involved, experimental difficulties, various dosage forms and the reasoning behind them, mechanism of action, quality assurance and role of regulatory agencies. After having a course based on this book, the student will be able to understand: 1) the career prospects in the pharmaceutical industry, 2) the need for interdisciplinary teamwork in science, 3) the techniques and technology involved in making pharmaceuticals starting from bulk drugs, and 4) different dosage forms and critical factors in the development of pharmaceutical formulations in relation to the principles of chemistry.A few blockbuster drugs including atorvastatin, sildanefil, ranitidine, ciprofloxacin, amoxicillin, and the longest serving drugs such as aspirin and paracetamol are discussed in detail. Finally, the book also covers the important current pharmaceutical issues like quality control, safety, counterfeiting and abuse of drugs, and future prospects for pharmaceutical industry. - Unified approach explaining drug discovery, bulk drug manufacturing, formulation of dosage forms, with pharmacological and therapeutic actions - Manufacturing processes of representative active pharmaceutical ingredients and their chemistry plus formulation of dosage forms presented in this book are based on actual industrial processes - Covers many aspects relevant to students of the pharmaceutical sciences or newly employed pharmaceutical researchers/employees. It contains summary information about regulatory agencies of different countries
Author |
: Geoffrey D Tovey |
Publisher |
: Royal Society of Chemistry |
Total Pages |
: 432 |
Release |
: 2018-06-25 |
ISBN-10 |
: 9781788014434 |
ISBN-13 |
: 178801443X |
Rating |
: 4/5 (34 Downloads) |
Synopsis Pharmaceutical Formulation by : Geoffrey D Tovey
Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety and stability of the final medicinal product. Modern formulation science deals with biologics as well as small molecules. Regulatory and quality demands, in addition to advances in processing technologies, result in growing challenges as well as possibilities for the field. Pharmaceutical Formulation provides an up to date source of information for all who wish to understand the principles and practice of formulation in the drug industry. The book provides an understanding of the links between formulation theory and the practicalities of processing in a commercial environment, giving researchers the knowledge to produce effective pharmaceutical products that can be approved and manufactured. The first chapters introduce readers to different dosage forms, including oral liquid products, topical products and solid dosage forms such as tablets and capsules. Subsequent chapters cover pharmaceutical coatings, controlled release drug delivery and dosage forms designed specifically for paediatric and geriatric patients. The final chapter provides an introduction to the vital role intellectual property plays in drug development. Covering modern processing methods and recent changes in the regulatory and quality demands of the industry, Pharmaceutical Formulation is an essential, up to date resource for students and researchers working in academia and in the pharmaceutical industry.
Author |
: Alexander Taylor Florence |
Publisher |
: Pharmaceutical Press |
Total Pages |
: 198 |
Release |
: 2010 |
ISBN-10 |
: 9780853696919 |
ISBN-13 |
: 0853696918 |
Rating |
: 4/5 (19 Downloads) |
Synopsis An Introduction to Clinical Pharmaceutics by : Alexander Taylor Florence
This textbook describes a variety of dosage forms and their clinical importance and use. The use and behaviour of dosage forms in different age groups and patient groups will also be considered along with recent developments such as personalised therapies and genomics. It contains relevant examples and clinical case studies.
Author |
: Gordon John Weston |
Publisher |
: |
Total Pages |
: |
Release |
: 1965 |
ISBN-10 |
: OCLC:959791952 |
ISBN-13 |
: |
Rating |
: 4/5 (52 Downloads) |
Synopsis An Introduction to the Pharmaceutical Formulation by : Gordon John Weston
Author |
: Thorsteinn Loftsson |
Publisher |
: Academic Press |
Total Pages |
: 170 |
Release |
: 2014-01-25 |
ISBN-10 |
: 9780124115620 |
ISBN-13 |
: 0124115624 |
Rating |
: 4/5 (20 Downloads) |
Synopsis Drug Stability for Pharmaceutical Scientists by : Thorsteinn Loftsson
Drug Stability for Pharmaceutical Scientists is a clear and easy-to-follow guide on drug degradation in pharmaceutical formulation. This book features valuable content on both aqueous and solid drug solutions, the stability of proteins and peptides, acid-base catalyzed and solvent catalyzed reactions, how drug formulation can influence drug stability, the influence of external factors on reaction rates and much more. Full of examples of real-life formulation problems and step-by-step calculations, this book is the ideal resource for graduate students, as well as scientists in the pharmaceutical and related industries. - Illustrates important theoretical concepts with numerous examples, figures, calculations, learning problems and questions for self-study and retention of material - Provides answers and explanations to test your knowledge - Enables you to better understand key concepts such as rate and order of reaction, reaction equilibrium, complex reaction mechanisms and more - Includes an in-depth discussion of both aqueous and solid drug solutions and contains the latest international regulatory requirements on drug stability
Author |
: Geoffrey D Tovey |
Publisher |
: Royal Society of Chemistry |
Total Pages |
: 359 |
Release |
: 2022-05-04 |
ISBN-10 |
: 9781839165610 |
ISBN-13 |
: 1839165618 |
Rating |
: 4/5 (10 Downloads) |
Synopsis Specialised Pharmaceutical Formulation by : Geoffrey D Tovey
Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety, and stability of the final medicinal product. Regulatory and quality demands, in addition to advances in processing technologies, result in growing challenges as well as possibilities for the field. Following on from Pharmaceutical Formulation, which covered traditional dosage forms such as tablets and capsules, this volume expands upon those formulations to cover a more diverse range of less common dosage forms. Novel routes of administration are covered from inhalational, dermal and transdermal formulations to ocular, oral suspensions, vaccines and nanoparticle drug delivery. The methods through which these formulations are processed and manufactured is also covered, providing essential knowledge to ensure quality, efficiency, and acceptable costing. Specialised Pharmaceutical Formulation is an essential, up to date resource for students and researchers working in academia and in the pharmaceutical industry and will equip readers with the ability to effectively and reliably produce products which can be approved, manufactured and made available to administer to patients.
Author |
: Reynir Eyjolfsson |
Publisher |
: Academic Press |
Total Pages |
: 68 |
Release |
: 2014-10-09 |
ISBN-10 |
: 9780128021873 |
ISBN-13 |
: 012802187X |
Rating |
: 4/5 (73 Downloads) |
Synopsis Design and Manufacture of Pharmaceutical Tablets by : Reynir Eyjolfsson
Design and Manufacture of Pharmaceutical Tablets offers real world solutions and outcomes of formulation and processing challenges of pharmaceutical tablets. This book includes numerous practical examples related to actual formulations that have been validated and marketed and covers important data in the areas of stability, dissolution, bioavailibity and processing. It provides important background and theoretical information on design and manufacturing and includes a full section dedicated to design experimental methodology and statistics. In addition, this book offers a a general discussion of excipients used in proper tablet design along with practical examples related to excipients. Drug development scientists in industry and academia, as well as students in the pharmaceutical sciences will greatly benefit from the practical knowledge and case examples provided throughout this book. - Incorporates important mathematical models and computational applications - Includes unique content on central composite design and augmented simplex lattice - Provides background on important design principles with emphasis on quality-based design (QBD) of pharmaceutical dosage forms
Author |
: Alok K. Kulshreshtha |
Publisher |
: Springer Science & Business Media |
Total Pages |
: 337 |
Release |
: 2009-11-05 |
ISBN-10 |
: 9781441910875 |
ISBN-13 |
: 1441910875 |
Rating |
: 4/5 (75 Downloads) |
Synopsis Pharmaceutical Suspensions by : Alok K. Kulshreshtha
The suspension dosage form has long been used for poorly soluble active ingre- ents for various therapeutic indications. Development of stable suspensions over the shelf life of the drug product continues to be a challenge on many fronts. A good understanding of the fundamentals of disperse systems is essential in the development of a suitable pharmaceutical suspension. The development of a s- pension dosage form follows a very complicated path. The selection of the proper excipients (surfactants, viscosity imparting agents etc.) is important. The particle size distribution in the finished drug product dosage form is a critical parameter that significantly impacts the bioavailability and pharmacokinetics of the product. Appropriate analytical methodologies and instruments (chromatographs, visco- ters, particle size analyzers, etc.) must be utilized to properly characterize the s- pension formulation. The development process continues with a successful scale-up of the manufacturing process. Regulatory agencies around the world require cli- cal trials to establish the safety and efficacy of the drug product. All of this devel- ment work should culminate into a regulatory filing in accordance with the regulatory guidelines. Pharmaceutical Suspensions, From Formulation Development to Manufacturing, in its organization, follows the development approach used widely in the pharmaceutical industry. The primary focus of this book is on the classical disperse system – poorly soluble active pharmaceutical ingredients s- pended in a suitable vehicle.