Advances in Tissue Banking is the only series of publications where producers and clinical users of tissues can learn in one place about developments in this interdisciplinary field. This important volume concentrates on the new leading topics, and bridges the tissue banking technology and the scientific developments, which fuel this rapidly growing field. It presents the regulatory controls being introduced in the USA, Europe and Japan, as well as the relationship among technical orthopaedics, in vitro tissue engineering, and osteoinduction. New subject areas in the volume include cell processing and preservation, particularly for islet and stem cells; preservation, processing and viability of vascular grafts; and gland transplantation. Collagen biochemistry is reviewed and linked to skin substitutes and skin banking. The volume fully reflects present global developments, with contributions from Spain, Japan, Russia, Poland, Estonia and the USA, among other countries.

This important book provides the only published information in the inter-disciplinary field of tissue banking. It gives comprehensive coverage of the regulatory framework of the subject, as well as production and sterilisation of tissue allografts, (bone, skin and new substitutes). The use of tissue allografts in orthopaedic and replacement surgery for the treatment of burns. etc. is described.

Advances in Tissue Banking is the first authoritative publication to encompass this interdisciplinary field, which is now providing hundreds of thousands of tissue grafts for transplant surgery every year worldwide (400,000 grafts in the USA alone annually). There is no text book which can be consulted about the subject, since the field has moved so rapidly over the past few years. The scientific and medical publications are scattered throughout specialised literature and are not readily accessible to all the diverse practitioners.This book, volume 1 of the new series, is written by experts on the subject. It is designed to fill the gap and provide a vehicle of communication for those participating in various aspects of the subject. Regulators are still in the process of coming to grips with the requirements to ensure safety and find a suitable definition within the legislative system for a “transplant tissue”. The various transplant donation systems in various countries differ. Allografts are used extensively in orthopaedic surgery, burns and wound healing. Heart valve banking has now established itself. Central to the subject is the prevention of the transmission of infection, with great emphasis being placed on the screening of donors, preservation and sterilisation of the tissues using the best and safest procedures.Nobody connected with regulating, producing, or using tissues can afford to be without the concentrated information so readily provided in this book, which is not available elsewhere. It will also be of great value to scientists and doctors who wish to learn about the subject and to introduce it into general scientific and medical education.

Advances in Tissue Engineering is a unique volume and the first of its kind to bring together leading names in the field of tissue engineering and stem cell research. A relatively young science, tissue engineering can be seen in both scientific and sociological contexts and successes in the field are now leading to clinical reality. This book attempts to define the path from basic science to practical application. A contribution from the UK Stem Cell Bank and opinions of venture capitalists offer a variety of viewpoints, and exciting new areas of stem cell biology are highlighted. With over fifty stellar contributors, this book presents the most up-to-date information in this very topical and exciting field./a

This important book discusses the need for gamma irradiation in the processing of tissue allografts. With particular emphasis on tissue banking in the Asia-Pacific region, it covers a wide range of issues in tissue banking, including the basic science of radiation, quality control of the irradiation process, and clinical applications of irradiated bone grafts and amnions.A compulsory textbook for the well-regarded Singapore-based IAEA/NUS Diploma Course in Tissue Banking, it is also a useful guide for tissue bankers in establishing quality systems in their banks. Whether they be tissue banking students, tissue graft producers, radiation scientists, or transplantation surgeons, readers of this book will discover the latest developments in this exciting interdisciplinary field.

Reproductive technologies to assist in both human conception and animal breeding are increasingly in demand. These technologies, along with the advent of tissue engineering, have propelled the challenges of tissue collection, preservation, and banking to the research forefront. Using examples drawn from reproductive technologies, Reproductive Tissue Banking presents the scientific principles underlying tissue banking. These examples serve as models for the technology of banking other living tissues, including blood, bone marrow, cornea, and skin. In discussing research emerging from their laboratories and those of others, the authors meld fundamentals of biology, chemistry, and physics with the latest discoveries in the field to give the reader profound insight into research directions and ethical considerations crucial to the advancement of tissue banking.With its emphasis on human applications and concerns, this book provides a valuable supplement to short courses on tissue preservation and tissue engineering. Researchers in reproductive medicine, animal and veterinary science, and cryobiology will find this book, with its extensive bibliography, a very handy reference.* * Written by leading international researchers* Provides insightful discussions on reproductive tissue banking* Presents comprehensive citations to relevant literature, both current and historic* Discusses in vitro preservation of spermatozoa, oocytes, embryos, and gonadal tissues of mammals* Contains coverage of ethical considerations from a discussion of the splitting of embryos to an exploration of the protection of biodiversity

This volume of tissue banking is the second of a series extending the interdisciplinary field. All of the authors of this book have been major contributors of scientific and medical publications in their respective specialities. There are articles covering blood transfusion; bone marrow and stem cell transplantation; immunology and the role of immunology in musculoskeletal transplantation, various aspects of cryopreservation of organs, cartilage and tendons; organ perfusion preservation; the history and long term follow-up of osteochondral allografts, both frozen and fresh; neurosurgical applications; cardiovascular applications; the use of skin and newer biological membranes for wound coverage.The book is of particular importance, in that it has been written in memory of Kenneth W Sell, MD, PhD, a pioneer and promulgator of tissue banking and transplantation. Many of the physicians, surgeons and scientists who trained under his leadership have gone on to distinguish themselves in the various aspects of transplantation. Many of them have contributed to this book, exemplifying the diversity of Dr Sell's contributions to tissue banking and transplantation.

This is the most comprehensive volume dealing with tissue banking presently available, with 27 contributions from the most distinguished and experienced practitioners in the field: surgeons, microbiologists and tissue bankers.Safety of allografts is now a major concern due to possible microbial and viral contamination of tissues, even in the most sophisticated centres. Thus, publication here of the International Atomic Energy Agency's Code of Practice for the Radiation Sterilisation of Tissues is important, as is their guidance on Standards and Public Awareness regarding this often misunderstood technology.The volume spans all the methodologies used in the field and covers a spectrum of tissues: bone, skin, cardiovascular grafts, corneal grafts and sperm banking. Of particular interest in these days of gigantic disasters is the evaluation of the value of an effective tissue bank during the Volendam burns disaster in the Netherlands and the horrific disaster in “Messa Redonda” Peru.Orthopaedics, as usual, has the premier usage of tissues and this volume is graced by a landmark contribution from that doyen of massive allograft surgery, Henry Mankin. Balancing out the US experience is a contribution from Russia, which outlines new approaches to using allograft and autograft bone.The motivation for such a comprehensive volume came at the congress held in Boston, which drew together all the international associations of tissue banking: American, Asia-Pacific, Latin American and European. The whole world has been harnessed to construct this outstanding and historic volume.

This series has now established itself as the leading publication on the multi-disciplinary subject of tissue banking. The high quality of the contributors and the broad coverage of the subject have continued in Volume 4. The material given in this volume is not presented anywhere else as systematically or as authoritatively.The essential feature in establishing confidence in the quality and safety of allografts is the manufacturing quality system utilised. This volume describes the most recent approach to good manufacturing control.Throughout the world, the old cottage approach to tissue banking is being abandoned, mainly due to the insistence by regulatory authorities that the procedures should be standardised and rigorous infection control applied. The experience in a number of countries is described in this volume, giving the reader quick access to developments in Argentina, Finland, Indonesia, Scotland and France. These represent a geographical and cultural spread of the developments.A balance needs to be struck between the use of allografts and of bone substitutes, depending on the clinical condition and the availability of grafts in a particular situation. The subject areas — such as mandibular reconstruction, spinal surgery, surgery and reconstruction of bone tumours and acetabular revision — covered in this volume demonstrate the universality of this technique. The use of allografts for the repair of knee ligaments has been and remains a controversial subject. The contributions on this subject will surely be an important and positive addition to this debate.

Advances in Tissue Banking is the only series of publications where producers and clinical users of tissues can learn in one place about developments in this interdisciplinary field. This important volume concentrates on the new leading topics, and bridges the tissue banking technology and the scientific developments, which fuel this rapidly growing field. It presents the regulatory controls being introduced in the USA, Europe and Japan, as well as the relationship among technical orthopaedics, in vitro tissue engineering, and osteoinduction. New subject areas in the volume include cell processing and preservation, particularly for islet and stem cells; preservation, processing and viability of vascular grafts; and gland transplantation. Collagen biochemistry is reviewed and linked to skin substitutes and skin banking. The volume fully reflects present global developments, with contributions from Spain, Japan, Russia, Poland, Estonia and the USA, among other countries.