In this compilation, the authors begin by highlighting the recent developments in asymmetric 1,4- and 1,2- additions to α, β-unsaturated carbonyl compounds. The recent finding of Cu (I)-catalyzed asymmetric 1,2-addition of Grignard reagents to α, β-unsaturated carbonyl compounds, as well as aromatic ketones, has categorically revolutionized catalytic asymmetric reactions.This compilation also aims to use the well-known coordination preference of zinc in phthalocyanine and porphyrin ligands in correlation with supramolecular systems. The light-absorption process in dye-sensitized solar cells is studied using the time-dependent density functional theory.In recent years, a series of investigations on detonation wave formation in acetylene have been published. In these studies, it was shown that the formation of detonation proceeds entirely due to the energy released during the condensation of carbon nanoparticles during the growth of poly-aromatic hydrocarbons. The results of these studies are summarized and practical applications are discussed.The authors discuss aromatic amines, derivatives of aromatic hydrocarbons containing an amino group/an amine group/nitrogen atom in their structures. These compounds represent one of the most important classes of industrial and environmental chemicals. Three groups have been studied: monocyclic, polycyclic, and heterocyclic aromatic amines, which are used as intermediates in azo dye manufacturing, pigments, drugs, antibiotics, antidepressants, pesticides, and other industrial products.In the closing study, the GC-MS/MS method has been developed for the determination and quantification of 35 multiclass pesticide residues in chili samples. Pesticides were selected from different families including organochlorines, organophosphorus, carbamates, pyrethroids, triazines, triazoles, and pyrazoles. The QuEChERS-dSPE method was used for the extraction of pesticide residue.

The authors' of this latest volume discuss recent advances in chemistry research. The chapters include discussions on a novel approach to developing a reliable optimised model for the estimation of PVT properties at various reservoir conditions; diverse dye removal technologies and recent progress in dye adsorption using activated carbon; the unique synthesis, properties and functions of mono- and di-nuclear ruthenium(II) aquo complexes; the detection of glycoproteins by widely used classical methods such as SDS-PAGE and Western blot; the predictability of the solubility of supercritical CO2 in ionic liquid; the impact of sucrose, stevia and xylitol on mechanical characteristics of gels prepared with different commercial chestnut flours; separated XRD analysis and non-linear optics for the interaction in composite materials of chiral cyanide bimetallic complexes and LiMnO2; and the oxidation of some sulphated macromolecules using various oxidising agents.

This edited volume comprises five chapters, each detailing recent updates in chemistry research. Chapter One describes different types of polymer electrolytes and their preparation methods as well as ion transport mechanisms, methods of improving properties, and techniques for evaluating their structure and properties. Chapter Two analyzes the scopes and limitations of chromatography, NMR spectroscopy, and UV spectroscopy for assigning fullerene C60 regioisomeric multiadducts. Chapter Three focuses on electrochemical techniques used for developing insulin sensors of high specificity and sensitivity. Chapter Four presents selected contemporary achievements of different computational methods in modeling of natural and newly synthesized compounds with determined antibacterial, antifungal and antiviral activities. Lastly, Chapter Five reviews some metal porphyrins of manganese, cobalt, vanadium, and chromium and their catalytic applications.

This new and important book presents recent advances in organometallic chemistry which is based on the reactions and use of a class of compounds (R-M) that contain a covalent bond between carbon and metal. They are prepared either by direct reaction of the metal with an organic compound or by replacement of a metal from another organometallic substance. Research in organometallic chemistry is also conducted in the areas of cluster synthesis, main-group derivatives in unusual oxidation states, organometallic polymers, unstable organometallic compounds and intermediates in matrices, structure determination of organometallic compounds in the solid state [X-ray diffraction] and gaseous states [electron diffraction], and mechanisms of reactions of transient silylenes and related species. In addition to the traditional metals and semimetals, elements such as selenium, lithium and magnesium are considered to form organometallic compounds, e.g. organomagnesium compounds MeMgI, iodo(methyl)magnesium and diethylmagnesium which are Grignard reagents an organo-lithium compound BuLi butyllithium; Organometallic compounds often find practical use as catalysts, the processing of petroleum products and the production of organic polymers.

Advances in Medicinal Chemistry Research is a book addressed to undergraduate and postgraduate students, where recent advances in the discovery and development of effective agents against the most remarkable wide-reaching diseases are presented, divided into seven chapters. This first edition of Advances in Medicinal Chemistry Research offers insights into medicinal chemistry that arguably have the most significant impact on our lives than any other. It draws together research on therapeutic agents from natural, synthetic, and virtual screening sources as starting points for the design of drugs against obesity, multidrug-resistant bacteria, neglected tropical diseases, Alzheimer, and cancer. From the prediction of promising hits and identification of active compounds to the extraction of more complex molecules, this book explores a range of essential topics to support the development of novel, economical, and efficacious therapeutics for these diseases, which currently affect a billion people worldwide. Beginning with an overview of obesity, showing the current research landscape, the books shows the importance of natural and synthetic products as promising anti-obesity agents. Subsequently, the medicinal chemistry of modulation of bacterial resistance is presented, focusing on the MFS, RND, ABC, and MATE superfamilies. The book goes on to discuss such topics as antituberculosis, antileishmanial, and anti-hepatitis thiophene-containing compounds, under the medicinal chemistry point of view. Also, potent human glutaminyl cyclase inhibitors are deeply discussed and displayed as hopeful anti-Alzheimer's agents. The last three chapters are focused on the development of researches involving new anticancer agents, initializing with LBDD, SBDD, QSAR, and QM/MM methods applied to the identification of novel promising anticancer compounds. Moreover, IDO1 inhibitors are exhaustively explored and analyzed as a new promise for the immunotherapy of cancer. Finally, a great update on Eg5 kinesin inhibitors is provided, exploring different chemical classes of synthetic and natural compounds, including miscellanea as a new approach for Eg5 inhibition. Combining the expertise of researchers from around the world, this volume aims to support and encourage researches for the development of novel, safe, and active agents against lipase enzyme, bacteria, neglected tropical diseases, Alzheimer, and cancer. The clear narrative truly engages the reader, holding their attention right from the opening of a chapter, and maintaining interest and understanding as a chapter leads into more complex material. Advances in Medicinal Chemistry Research is a book that reviews ongoing developments and recent cutting-edge advances in medicinal chemistry of the most relevant diseases found nowadays, underlining how medicinal chemistry research continues to make significant contributions to the discovery and development of new therapeutic entities. Key Features â¢Chapters written by active specialists and leading experts deeply engaged in the research field of most deadly and limiting diseases for drug discovery. â¢Draws together cutting-edge research advances in medicinal chemistry focused at the obesity, multidrug-resistant microorganisms, Alzheimer, and cancer in a single volume. â¢Highlights the future potential of researches for the medicinal chemistry of most impactful diseases today. â¢Contents addressed to medicinal chemistry, biochemistry, biology, and pharmacy students, professors, and researchers.

'Advances in Chemistry Research' presents original research results on the leading edge of chemistry research. Each article has been carefully selected in an attempt to present substantial research results across a broad spectrum.

Advances in Chemistry Research. Volume 62 first provides information related to the synthesis, morphology, crystal structure, and porosity of bentonite and bentonite/magnetite powders. Following this, the authors discuss carbon tetrachloride, a clear, colourless, volatile and very stable chlorinated hydrocarbon with a non-polar nature, making it an excellent solvent.Recent research on the applications of hydrogen peroxide as oxidizing and reducing agent is presented, as well as its application in biocatalysis, as signaling molecule, and in nanochemistry.The mode of action hydrogen peroxide induces in yeast apoptosis is also addressed, including overexpression of apoptosis inducing factor homologue proteins.Additionally, this compilation describes the recent advances concerning the use of hydrogen peroxide in heteropolyacid-catalyzed oxidation reactions of terpenic alcohols, which are renewable origin compounds whose oxidation provides aldehydes and epoxides.Diamines, organic compounds with two amino groups, are described. In one study, different diamines are synthesized with complex formulas used in the preparation of different thermally stable polymers.A few diamines used in developing thin-film polyamide composite membranes are reviewed.The concluding study is focused on gas hydrates, mixtures of light gases such as methane, ethane or carbon dioxide, and water molecules under a special temperature and pressure condition, forming a liquid-like material.

This book presents original research results on the leading edge of chemistry research. Each article has been carefully selected in an attempt to present substantial research results across a broad spectrum. Topics discussed include molecular cluster ensembles in biomatrices and the influence of ETIs; application of spectroscopic techniques in the quality control of pharmaceuticals; beer analyses in each step of the commercial production process; the properties of coagulation, flocculation, agglutination and hemagglutination; applications and uses of formic acid in liquid chromatography-mass spectrometry analysis; applications of the theory of joint probability distributions to chemical science engineering; nutritional variation in the process of brewing pilsner beer; the long-range order in MnSO4 water solutions; and the electrolytic dissociation of alkyl and aryl derivatives of malonic acid.