Practical rather than theoretical, it provides epidemiologists and other health workers with a good basic knowledge of sampling principles and methods and their potential in the medical field. Focusing on the determination of adequate sample sizes under different situations, the book is divided into two parts; the first provides solutions to typical problems of various survey and study designs, and the second offers a clear, concise exposition of the theory behind the processes of determining sample size. Features many reference tables.

The Handbook of Epidemiology provides a comprehensive overview of the field and thus bridges the gap between standard textbooks of epidemiology and dispersed publications for specialists that have a narrowed focus on specific areas. It reviews the key issues and methodological approaches pertinent to the field for which the reader pursues an expatiated overview. It thus serves both as a first orientation for the interested reader and as a starting point for an in-depth study of a specific area, as well as a quick reference and recapitulatory overview for the expert. The book includes topics that are usually missing in standard textbooks.

This is an open access book. The book provides an overview of the state of research in developing countries – Africa, Latin America, and Asia (especially India) and why research and publications are important in these regions. It addresses budding but struggling academics in low and middle-income countries. It is written mainly by senior colleagues who have experienced and recognized the challenges with design, documentation, and publication of health research in the developing world. The book includes short chapters providing insight into planning research at the undergraduate or postgraduate level, issues related to research ethics, and conduct of clinical trials. It also serves as a guide towards establishing a research question and research methodology. It covers important concepts such as writing a paper, the submission process, dealing with rejection and revisions, and covers additional topics such as planning lectures and presentations. The book will be useful for graduates, postgraduates, teachers as well as physicians and practitioners all over the developing world who are interested in academic medicine and wish to do medical research.

The National Human Monitoring Program (NHMP) identifies concentrations of specific chemicals in human tissues, including toxicologic testing and risk assessment determinations. This volume evaluates the current activities of the NHMP; identifies important scientific, technical, and programmatic issues; and makes recommendations regarding the design of the program and use of its products.

This book provides statisticians and researchers with the statistical tools - equations, formulae and numerical tables - to design and plan clinical studies and carry out accurate, reliable and reproducible analysis of the data so obtained. There is no way around this as incorrect procedure in clinical studies means that the researcher's paper will not be accepted by a peer-reviewed journal. Planning and analysing clinical studies is a very complicated business and this book provides indispensible factual information. Please go to http://booksupport.wiley.com and enter 9781405146500 to easily download the supporting materials.

This manual presents the practical and statistical information needed to help investigators decide how large a sample to select from a population targeted for a health study or survey. Designed to perform a "cookbook" function, the book uses explanatory text and abundant tabular calculations to vastly simplify the task of determining the minimum sample size needed to obtain statistically valid results. The objective is to assist those investigators, undertaking health studies at local or district level, who lack detailed knowledge of statistical methodology. Acknowledging that the size of a sample will depend on the aims, nature, and scope of the study, the first part of the book provides a practical farmework for working through the steps of sample size determination once a proposed study and its objectives have been clearly defined. The second part of the book features more than 50 pages of tables that enable the reader to determine the sample size required, under simple random sampling, in a given type of study without recourse to complicated calculations.

This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)

Sampling is fundamental to nearly every study in the social and policy sciences, yet clear, concise guidance for practitioners and graduate students has been difficult to find. Practical Sampling provides guidance for researchers dealing with the everyday problems of sampling. Using the practical design approach Henry integrates sampling into the overall research design and explains the interrelationships between research design and sampling choices. He lays out alternatives and implications of the choices using four detailed examples to illustrate the alternatives selected and the trade-offs made by applied researchers. The author uses a narrative, conceptual approach throughout the book; mathematical presentations are limited to necessary formulas; and calculations are kept to the absolute minimum, making it an easily approachable book for any researcher, student or professional across the social sciences.

Features: Comprehensive coverage of sample size calculations, including Normal, binary, ordinal, and survival outcome data Covers superiority, equivalence, non-inferiority, bioequivalence and precision objectives for both parallel group and crossover designs Highlights how trial objectives impact the study design with respect to both the derivation of sample formulae and the size of the study Motivated with examples of real-life clinical trials showing how the calculations can be applied New edition is extended with all chapters revised, some substantially, and four completely new chapters on multiplicity, cluster trials, pilot studies, and single arm trials

Sample Size Calculations: Practical Methods for Engineers and Scientists presents power and sample size calculations for common statistical analyses including methods for means, standard deviations, proportions, counts, regression, correlation, and measures of agreement. Topics of special interest to quality engineering professionals include designed experiments, reliability studies, statistical process control, acceptance sampling, process capability analysis, statistical tolerancing, and gage error studies. The book emphasizes approximate methods, but exact methods are presented when the approximate methods fail. Monte Carlo and bootstrap methods are introduced for situations that don't satisfy the assumptions of the analytical methods. Solutions are presented for more than 170 example problems and solutions for selected example problems using PASS, MINITAB, Piface, and R are posted on the Internet.