From electromagnetic field theory for tissue heating... to simulations of adaptive phased array thermotherapy for deep tumors of the torso... to coverage of arrays for tumors in the head, neck, breast, and chest wall, this timely resource offers you expert guidance in this emerging area.

Hyperthermia or heat therapy is emerging as a powerful modality in the fight against cancer, especially when it is used as an adjuvant to conventional radiation or chemotherapy treatments. However, the main challenge in hyperthermia treatment is the accurate targeting of the tumor area, and this project is focused on improving the efficiency of hyperthermia systems by the use of focusing structures. The heating is actually concentrated through the use of fabricated metal structures in shape of a cone or a cylinder, which are appended to the 27 MHz Mettler diathermy system. The heating effectiveness is measured, using a digital thermometer on a Absorber surface whose electrical properties are identical to the biological human tissue. Several heating studies were carried out to evaluate the effects of using the focusing structures, and will be detailed in the report.

Thermoregulation, Part II: From Basic Neuroscience to Clinical Neurology, Volume 155, not only reviews how body temperature regulation changes in neurological diseases, but also how this aspect affects the course and outcomes of each disease. Other sections of the volume review three therapeutic approaches that are aimed at manipulating body temperature, including induced hypothermia, induced hyperthermia and antipyretic therapy. The book is comprised of nine sections across two volumes, five dealing with the basic aspects of body temperature regulation and four dealing with the clinical aspects. Basic sections cover the Thermoregulation system, Thermoreceptors, Thermoeffectors, Neural pathways, and Thermoregulation as a homeostatic function. In addition, the book covers the physiology and neuroanatomy of the thermoregulation system and provides descriptions of how the regulation of body temperature intervenes with other physiological functions (such as sleep, osmoregulation, and immunity), stress, exercise and aging. Basic sections serve as an introduction to the four clinical sections: Body Temperature, Clinical Significance, Abnormal Body Temperature, Thermoregulation in Neurological Disease and Therapeutic Interventions. - Presents a clear, logical pathway from the fundamental physiology of thermoregulation, through neurobiology, to clinical applications and disease - Enables researchers and clinicians to better understand the value of temperature measurement in disease and the use of temperature as a therapy - Integrates content from a broad field of research, including topics on the molecular physiology of temperature receptors, to the management of accidental hypothermia

Breast cancer is the most common form of cancer among women. Conventional drugtreatment for breast cancer, chemotherapy would destroy the cancer cells because of themedicine targets on rapidly dividing cells. However, healthy cells and tissues in blood,mouth, intestinal tract, nose, nails and hair also divide rapidly, they could be damaged.Hyperthermia therapy refer to body temperature elevated to damage cancer cells. It isalways used with other forms of cancer therapy, such as radiation therapy andchemotherapy. In hyperthermia, different types of energy may be used to apply heat,including microwave, laser, ultrasound and magnetic fields. Available software's for thesimulation and study the effect of magnetic field on the tumour and how SAR changeswith the change of heat input are COMSOL, MIMICS, &MAGICS. The Dicom imagesof breast cancer are imported to MIMICS and 3d model is created and MAGICS is usedfor improvements to the surface and them geometry is imported to COMSOL for thestudy of the physics and to simulated the effect of hyperthermia in tumour. The resultsindicate that a more concentrated nanoparticles distribution is better in damagingdiseased tissue than the uniform distribution is better than the concentration under lowheating power. A more uniform distribution is better than the concentrated distributionunder high heating power. For concentrated nanoparticles distribution, the location wherethe nanoparticles are concentrated influences tissue damage: a more centred one has abetter effect. Radio-Frequency therapy is a common treatment in the cancer therapy. Thegoal of paper is to study the effect of electromagnetic waves on the liver cancer tissue.This liver model will allow us to examine the effect of temperature raise, temperatureprofile and Specific Absorption Ratio. In Microwave hyperthermia therapy, soft tissuesare targeted for the short duration of time which is responsible for the coagulation ofcancerous cell. In this review, the microwave coaxial antenna operating at the frequencyof 2.4GHz by varying the opening size of the antenna for the removal of the tumor.

From engineering fundamentals to cutting-edge clinical applications This book examines the biological effects of RF/microwaves and their medical applications. Readers will discover new developments in therapeutic applications in such areas as cardiology, urology, surgery, ophthalmology, and oncology. The authors also present developing applications in such areas as cancer detection and organ imaging. Focusing on frequency ranges from 100 kHz to 10 GHz, RF/Microwave Interaction with Biological Tissues is divided into six chapters: * Fundamentals in Electromagnetics--examines penetration of RF/microwaves into biological tissues; skin effect; relaxation effects in materials and the Cole-Cole model (display); the near field of an antenna; blackbody radiation and the various associated laws; and microwave measurements. * RF/Microwave Interaction Mechanisms in Biological Materials--includes a section devoted to the fundamentals of thermodynamics and a discussion on energy and entropy. * Biological Effects--investigates the effects of radio frequency fields on the nervous system, the brain and spinal cord, the blood-brain barrier, and cells and membranes. * Thermal Therapy--includes a description of applicators and an extensive discussion on the foundation of dielectric heating and inductive heating. * EM-Wave Absorbers Protecting the Biological and Medical Environment--investigates materials for EM-wave absorbers from both a theoretical and applications perspective. Special attention is given to ferrite absorbers. * RF/Microwave Delivery Systems for Therapeutic Applications--begins with the fundamental features of major components used in RF/microwave delivery systems for therapeutic applications. New research towards the development of future measurement techniques is also presented. The book features problem sets at the end of each chapter, making it an excellent introduction for bioengineering and engineering students. Researchers, physicians, and technicians in the field will also find this an excellent reference that offers all the fundamentals, the most cutting-edge applications, and insight into future developments. An Instructor's Manual presenting detailed solutions to all the problems in the book is available from the Wiley editorial department.

Hyperthermia has been found to be of great benefit in combination with radiation therapy or chemotherapy in the management of patients with difficult and com plicated tumor problems. It has been demonstrated to increase the efficacy, of ionising radiation when used locally but also has been of help in combination with systemic chemotherapy where hyperthermia is carried out to the total body. Problems remain with regard to maximizing the effects of hyperthermia as in fluenced by blood flow, heat loss, etc. The present volume defines the current knowledge relative to hyperthermia with radiation therapy and/or chemotherapy, giving a comprehensive overview of its use in cancer management. Philadelphia/Hamburg, June 1995 L.W. BRADY H.-P. HEILMANN Preface In an attempt to overcome tumor resistance, hypoxia, or unfavorable tumor condi tions, oncological research has come to focus on gene therapy, immunotherapy, new cytotoxic agents, and increasingly sophisticated radiotherapy. Radiation research has been directed towards heavy particle therapy and modification of the radiation response by either protecting or sensitizing agents. Improved dose localization using rotational or conformal strategies has also been implemented. Recently, changes in radiation fractionation schedules have shown promise of better results. Hyperthermia in cancer therapy can be viewed similarly as another means to increase the sensitivity of tumors to radio- and chemotherapy.