Polio--often called the "summer plague"--struck hundreds of thousands of children around the world between its emergence as an epidemic disease in 1916 to its cure in the 1950s. Today, images of children with crutches and leg braces or encased to their necks in iron lungs may be little more than a painful memory. Yet during its height the disease induced panic on a scale reminiscent of the great plagues of history. This book is the most comprehensive and compelling account of the century's polio epidemics yet written. Interweaving biographical, political, social, and medical history, Tony Gould--a distinguished British writer and himself a polio survivor--traces the rise and fall of the epidemics and describes the individuals who were influential in its treatment and conquest. He tells of Franklin D. Roosevelt, the most celebrated polio sufferer of all, who set up his own hydrotherapy center at Warm Springs in Georgia; John Enders, the Nobel prizewinner who made the crucial breakthrough in the laboratory; FDR's lieutenant, Basil O'Connor, whose "March of Dimes" became a byword for successful fund-raising; Sister Elizabeth Kenny, the larger-than-life nurse from the Australian outback who challenged medical orthodoxy and invented "miracle" cures; and finally the scientific rivals Jonas Salk and Albert Sabin, caught in a dramatic race to produce a viable vaccine. Gould then examines the experience of polio survivors on both sides of the Atlantic, including a moving autobiographical account of his own struggle with the disease and resulting disability. Although the disease has been eliminated in the West, it has not disappeared: paralytic polio remains a scourge in India, the Far East, and parts of Africa. And there are new worries that fatigue and accelerated muscular weakness--a "post-polio syndrome"--has come to afflict survivors three or four decades after the initial attack. Gould's powerful book, published forty years after the successful trial of the Salk vaccine, helps us to understand the savage and continuing impact of polio.

The plague outbreak of 1636 in Newcastle-upon-Tyne was one of the most devastating in English history. This hugely moving study looks in detail at its impact on the city through the eyes of a man who stayed as others fled: the scrivener Ralph Tailor. As a scrivener Tailor was responsible for many of the wills and inventories of his fellow citizens. By listening to and writing down the final wishes of the dying, the young scrivener often became the principal provider of comfort in people’s last hours. Drawing on the rich records left by Tailor during the course of his work along with many other sources, Keith Wrightson vividly reconstructs life in the early modern city during a time of crisis and envisions what such a calamitous decimation of the population must have meant for personal, familial, and social relations.

From the the winner of the Nobel Prize in Literature: Part detective story, part historical epic—a bold and brilliant novel that imagines a plague ravaging a fictional island in the Ottoman Empire. It is April 1900, in the Levant, on the imaginary island of Mingheria—the twenty-ninth state of the Ottoman Empire—located in the eastern Mediterranean between Crete and Cyprus. Half the population is Muslim, the other half are Orthodox Greeks, and tension is high between the two. When a plague arrives—brought either by Muslim pilgrims returning from the Mecca or by merchant vessels coming from Alexandria—the island revolts. To stop the epidemic, the Ottoman sultan Abdul Hamid II sends his most accomplished quarantine expert to the island—an Orthodox Christian. Some of the Muslims, including followers of a popular religious sect and its leader Sheikh Hamdullah, refuse to take precautions or respect the quarantine. And then a murder occurs. As the plague continues its rapid spread, the Sultan sends a second doctor to the island, this time a Muslim, and strict quarantine measures are declared. But the incompetence of the island’s governor and local administration and the people’s refusal to respect the bans doom the quarantine to failure, and the death count continues to rise. Faced with the danger that the plague might spread to the West and to Istanbul, the Sultan bows to international pressure and allows foreign and Ottoman warships to blockade the island. Now the people of Mingheria are on their own, and they must find a way to defeat the plague themselves. Steeped in history and rife with suspense, Nights of Plague is an epic story set more than one hundred years ago, with themes that feel remarkably contemporary.

During Medieval times, the Black Death wiped out one-fifth of the world's population. Four centuries later, in 1665, the plague returned with a vengeance, cutting a long and deadly swathe through the British Isles. In this title, the author focuses on Cambridge, where every death was a singular blow affecting the entire community.

NATIONAL BESTSELLER • From the New York Times bestselling author of The Flight Attendant comes a twisting story of love and deceit: an American man vanishes on a rural road in Vietnam, and his girlfriend follows a path that leads her home to the very hospital where they met. Alexis and Austin don’t have a typical “meet cute”—their first encounter involves Alexis, an emergency room doctor, suturing a bullet wound in Austin’s arm. Six months later, they’re on a romantic getaway in Vietnam: a bike tour on which Austin can show Alexis his passion for cycling, and can pay his respects to the place where his father and uncle fought in the war. But then Austin fails to return from a solo ride. Alexis’s boyfriend has vanished, the only clue left behind a bright yellow energy gel dropped on the road. As Alexis grapples with this bewildering loss, she starts to uncover a series of strange lies that force her to wonder: Where did Austin go? Why did he really bring her to Vietnam? And how much danger has he left her in? Set amidst the adrenaline-fueled world of the emergency room, The Red Lotus is a global thriller about those who dedicate their lives to saving people—and those who peddle death to the highest bidder. Look for Chris Bohjalian's new novel, The Lioness!

In a sensual paranormal romance, a teen girl’s doppelgänger from 1348 Florence lures her into the past in hopes of exacting a deadly trade. It was meant to be a diversion — a summer in Florence with her best friend, Liam, and his travel-writer mom, doing historical research between breaks for gelato. A chance to forget that back in Vermont, May’s parents, and all semblance of safety, were breaking up. But when May wakes one night sensing someone in her room, only to find her ghostly twin staring back at her, normalcy becomes a distant memory. And when later she follows the menacing Cristofana through a portale to fourteenth-century Florence, May never expects to find safety in the eyes of Marco, a soulful painter who awakens in her a burning desire and makes her feel truly seen. The wily Cristofana wants nothing less of May than to inhabit each other’s lives, but with the Black Death ravaging Old Florence, can May’s longing for Marco’s touch be anything but madness? Lush with atmosphere both passionate and eerie, this evocative tale follows a girl on the brink of womanhood as she dares to transcend the familiar — and discovers her sensual power.

From the acclaimed author of Miracle Cure and The Third Horseman, the epic story of the collision between one of nature's smallest organisms and history's mightiest empire During the golden age of the Roman Empire, Emperor Justinian reigned over a territory that stretched from Italy to North Africa. It was the zenith of his achievements and the last of them. In 542 AD, the bubonic plague struck. In weeks, the glorious classical world of Justinian had been plunged into the medieval and modern Europe was born. At its height, five thousand people died every day in Constantinople. Cities were completely depopulated. It was the first pandemic the world had ever known and it left its indelible mark: when the plague finally ended, more than 25 million people were dead. Weaving together history, microbiology, ecology, jurisprudence, theology, and epidemiology, Justinian's Flea is a unique and sweeping account of the little known event that changed the course of a continent.

This is the first systematic scholarly study of the Ottoman experience of plague during the Black Death pandemic and the centuries that followed. Using a wealth of archival and narrative sources, including medical treatises, hagiographies, and travelers' accounts, as well as recent scientific research, Nükhet Varlik demonstrates how plague interacted with the environmental, social, and political structures of the Ottoman Empire from the late medieval through the early modern era. The book argues that the empire's growth transformed the epidemiological patterns of plague by bringing diverse ecological zones into interaction and by intensifying the mobilities of exchange among both human and non-human agents. Varlik maintains that persistent plagues elicited new forms of cultural imagination and expression, as well as a new body of knowledge about the disease. In turn, this new consciousness sharpened the Ottoman administrative response to the plague, while contributing to the makings of an early modern state.

Like Winchester's Krakatoa, The Year Without Summer reveals a year of dramatic global change long forgotten by history In the tradition of Krakatoa, The World Without Us, and Guns, Germs and Steel comes a sweeping history of the year that became known as 18-hundred-and-froze-to-death. 1816 was a remarkable year—mostly for the fact that there was no summer. As a result of a volcanic eruption in Indonesia, weather patterns were disrupted worldwide for months, allowing for excessive rain, frost, and snowfall through much of the Northeastern U.S. and Europe in the summer of 1816. In the U.S., the extraordinary weather produced food shortages, religious revivals, and extensive migration from New England to the Midwest. In Europe, the cold and wet summer led to famine, food riots, the transformation of stable communities into wandering beggars, and one of the worst typhus epidemics in history. 1816 was the year Frankenstein was written. It was also the year Turner painted his fiery sunsets. All of these things are linked to global climate change—something we are quite aware of now, but that was utterly mysterious to people in the nineteenth century, who concocted all sorts of reasons for such an ungenial season. Making use of a wealth of source material and employing a compelling narrative approach featuring peasants and royalty, politicians, writers, and scientists, The Year Without Summer by William K. Klingaman and Nicholas P. Klingaman examines not only the climate change engendered by this event, but also its effects on politics, the economy, the arts, and social structures.

The veteran Wall Street Journal science reporter Marilyn Chase’s fascinating account of an outbreak of bubonic plague in late Victorian San Francisco is a real-life thriller that resonates in today’s headlines. The Barbary Plague transports us to the Gold Rush boomtown in 1900, at the end of the city’s Gilded Age. With a deep understanding of the effects on public health of politics, race, and geography, Chase shows how one city triumphed over perhaps the most frightening and deadly of all scourges.