Experiment: A child is deliberately infected with the deadly smallpox disease without his parents' informed consent. Result: The world's first vaccine. Experiment: A slave woman is forced to undergo more than thirty operations without anesthesia. Result: The beginnings of modern gynecology. Incidents like these paved the way for crucial, lifesaving medical discoveries. But they also harmed and humiliated their test subjects, many of whom did not agree to the experiments in the first place. How do doctors balance the need to test new medicines and procedures with their ethical duty to protect the rights of human subjects? Take a harrowing journey through some of history's greatest medical advances?and its most horrifying medical atrocities?to discover how human suffering has gone hand in hand with medical advancement.

An urgent, illuminating exploration of the social nature of shame and of how it might be used to promote large-scale political change and social reform. “[Jacquet] exposes the ways shame plays into collective ideas of punishment and reward, and the social mechanisms that dictate the ways we dictate our behavior.” —The Boston Globe Examining how we can retrofit the art of shaming for the age of social media, Jennifer Jacquet shows that we can challenge corporations and even governments to change policies and behaviors that are detrimental to the environment. Urgent and illuminating, Is Shame Necessary? offers an entirely new understanding of how shame, when applied in the right way and at the right time, has the capacity to keep us from failing our planet and, ultimately, from failing ourselves.

From author Frank Herbert, creator of the Dune series, comes this classic science fiction of a sadistic experiment created by a interstellar civilization ... THE DOSADI EXPERIMENT Beyond the God Wall Generations of a tormented human-alien people, caged on a toxic planet, conditioned by constant hunger and war-this is the Dosadi Experiment, and it has succeeded too well. For the Dosadi have bred for Vengeance as well as cunning, and they have learned how to pass through the shimmering God Wall to exact their dreadful revenge on the Universe that created them . . . At the Publisher's request, this title is being sold without Digital Rights Management Software (DRM) applied.

During the Cold War, an alliance between American scientists, pharmaceutical companies, and the US military pushed the medical establishment into ethically fraught territory. Doctors and scientists at prestigious institutions were pressured to produce medical advances to compete with the perceived threats coming from the Soviet Union. In Against Their Will, authors Allen Hornblum, Judith Newman, and Gregory Dober reveal the little-known history of unethical and dangerous medical experimentation on children in the United States. Through rare interviews and the personal correspondence of renowned medical investigators, they document how children—both normal and those termed "feebleminded"—from infants to teenagers, became human research subjects in terrifying experiments. They were drafted as "volunteers" to test vaccines, doused with ringworm, subjected to electric shock, and given lobotomies. They were also fed radioactive isotopes and exposed to chemical warfare agents. This groundbreaking book shows how institutional superintendents influenced by eugenics often turned these children over to scientific researchers without a second thought. Based on years of archival work and numerous interviews with both scientific researchers and former test subjects, this is a fascinating and disturbing look at the dark underbelly of American medical history.

FINALIST FOR THE GOVERNOR GENERAL'S AWARD FOR NON-FICTION Interrogating our ideas of race through the lens of her own multi-racial identity, critically acclaimed novelist Tessa McWatt turns her eye on herself, her body and this world in a powerful new work of non-fiction. Tessa McWatt has been called Susie Wong, Pocahontas and "black bitch," and has been judged not black enough by people who assume she straightens her hair. Now, through a close examination of her own body--nose, lips, hair, skin, eyes, ass, bones and blood--which holds up a mirror to the way culture reads all bodies, she asks why we persist in thinking in terms of race today when racism is killing us. Her grandmother's family fled southern China for British Guiana after her great uncle was shot in his own dentist's chair during the First Sino-Japanese War. McWatt is made of this woman and more: those who arrived in British Guiana from India as indentured labour and those who were brought from Africa as cargo to work on the sugar plantations; colonists and those whom colonialism displaced. How do you tick a box on a census form or job application when your ancestry is Scottish, English, French, Portuguese, Indian, Amerindian, African and Chinese? How do you finally answer a question first posed to you in grade school: "What are you?" And where do you find a sense of belonging in a supposedly "post-racial" world where shadism, fear of blackness, identity politics and call-out culture vie with each other noisily, relentlessly and still lethally? Shame on Me is a personal and powerful exploration of history and identity, colour and desire from a writer who, having been plagued with confusion about her race all her life, has at last found kinship and solidarity in story.

This book is 97.5% true. It tells of a man’s great escape from modern techno-life, as well as a desire to prove that John Donne, the 17th Century preacher, is a total loser. All ‘men’ are islands, dear John. The story occurs in a bitter jungle full of leeches, talking carpet pythons and very annoying Christians. It is a story about pain and beauty, prison and freedom, torture and love – life, in other words.

Testing is a surefire way to dramatically improve your website’s conversion rate and increase revenue. When you run experiments with changes to design or content, you’ll quickly discover which changes better motivate your users to take action. This book shows how to learn from your customers’ behavior and decisions, and how their responses reveal the strengths and weaknesses of your site. It will show you how to make websites that work harder and convert better. Experiment! will inspire you to challenge assumptions and start experimenting right now. You will: Learn how to approach experiments to improve conversion Understand the various methods of testing including A/B and multivariate Discover experiment ideas, and go beyond optimization to innovation Recognize the UX and design implications of experimenting Learn to analyze data and deliver results Experimenting changes the way you think about design and the way you work. It helps prevent the loudest voice from deciding direction; instead, through an experiment, you’ll ask the most important voices--your customers--“What do you think?”

First published in 2007 with the title: I thought it was just me: women reclaiming power and courage in a culture of shame.

A New York Times Book Review Notable Book of the Year It was the year after Chappaquiddick, and all spring Carmel McBain had watery dreams about the disaster. Now she, Karina, and Julianne were escaping the dreary English countryside for a London University hall of residence. Interspersing accounts of her current position as a university student with recollections of her childhood and an ever difficult relationship with her longtime schoolmate Karina, Carmel reflects on a generation of girls desiring the power of men, but fearful of abandoning what is expected and proper. When these bright but confused young women land in late 1960s London, they are confronted with a slew of new preoccupations--sex, politics, food, and fertility--and a pointless grotesque tragedy of their own. Hilary Mantel's magnificent novel examines the pressures on women during the early days of contemporary feminism to excel--but not be too successful--in England's complex hierarchy of class and status.

Ye Feng, who once stood at the peak of the world and made the world tremble. Conspiracy had allowed him to be reborn into a useless cripple with the same surname and surname. And to see, how could Ye Feng return to the peak from being a loser. As long as I, Ye Feng, am not dead, I will make the world cry.