A wry, witty account of what it is like to face death—and be restored to life. After being diagnosed in her early 40s with metastatic melanoma—a "rapidly fatal" form of cancer—journalist and mother of two Mary Elizabeth Williams finds herself in a race against the clock. She takes a once-in-a-lifetime chance and joins a clinical trial for immunotherapy, a revolutionary drug regimen that trains the body to vanquish malignant cells. Astonishingly, her cancer disappears entirely in just a few weeks. But at the same time, her best friend embarks on a cancer journey of her own—with very different results. Williams's experiences as a patient and a medical test subject reveal with stark honesty what it takes to weather disease, the extraordinary new developments that are rewriting the rules of science—and the healing power of human connection.

After being diagnosed in her early 40s with metastatic melanoma a "rapidly fatal" form of cancer journalist and mother of two Mary Elizabeth Williams finds herself in a race against the clock. She takes a once-in-a-lifetime chance and joins a clinical trial for immunotherapy, a revolutionary drug regimen that trains the body to vanquish malignant cells. Astonishingly, her cancer disappears entirely in just a few weeks. But at the same time, her best friend embarks on a cancer journey of her own - with very different results. Williams's experiences as a patient and a medical test subject reveal with stark honesty what it takes to weather disease, the extraordinary new developments that are rewriting the rules of science - and the healing power of human connection

NAMED ONE OF THE BEST BOOKS OF THE YEAR BY People ∙ O: The Oprah Magazine ∙ Financial Times ∙ Kansas City Star ∙ BookPage ∙ Kirkus Reviews ∙ Publishers Weekly ∙ Booklist NEW YORK TIMES BESTSELLER “A stunner.”—Justin Cronin “It’s never the disasters you see coming that finally come to pass—it’s the ones you don’t expect at all,” says Julia, in this spellbinding novel of catastrophe and survival by a superb new writer. Luminous, suspenseful, unforgettable, The Age of Miracles tells the haunting and beautiful story of Julia and her family as they struggle to live in a time of extraordinary change. On an ordinary Saturday in a California suburb, Julia awakes to discover that something has happened to the rotation of the earth. The days and nights are growing longer and longer; gravity is affected; the birds, the tides, human behavior, and cosmic rhythms are thrown into disarray. In a world that seems filled with danger and loss, Julia also must face surprising developments in herself, and in her personal world—divisions widening between her parents, strange behavior by her friends, the pain and vulnerability of first love, a growing sense of isolation, and a surprising, rebellious new strength. With crystalline prose and the indelible magic of a born storyteller, Karen Thompson Walker gives us a breathtaking portrait of people finding ways to go on in an ever-evolving world. “Gripping drama . . . flawlessly written; it could be the most assured debut by an American writer since Jennifer Egan’s Emerald City.”—The Denver Post “Pure magnificence.”—Nathan Englander “Provides solace with its wisdom, compassion, and elegance.”—Curtis Sittenfeld “Riveting, heartbreaking, profoundly moving.”—Kirkus Reviews (starred review) Look for special features inside. Join the Circle for author chats and more.

Subtitle in pre-publication: A memoir of friendship, sex, and murder in the Hollywood Hills.

Find out how people have learned to cope with their troubles and have become stronger by the very act of overcoming obstacles and surviving catastrophes. These are their stories, written by the people who lived them, their families, or those who helped them save the day.

“An unforgettable journey through this twisted miracle of evolution we call ‘our body.’” —Spike Carlsen, author of A Walk Around the Block From blurry vision to crooked teeth, ACLs that tear at alarming rates and spines that seem to spend a lifetime falling apart, it’s a curious thing that human beings have beaten the odds as a species. After all, we’re the only survivors on our branch of the tree of life. The flaws in our makeup raise more than a few questions, and this detailed foray into the many twists and turns of our ancestral past includes no shortage of curiosity and humor to find the answers. Why is it that human mothers have such a life-endangering experience giving birth? Why are there entire medical specialties for teeth and feet? And why is it that human babies can’t even hold their heads up, but horses are trotting around minutes after they’re born? In this funny, wide-ranging and often surprising book, biologist Alex Bezzerides tells us just where we inherited our adaptable, achy, brilliant bodies in the process of evolution.

A wry, witty account of what it is like to face death--and be restored to life. After being diagnosed in her early 40s with metastatic melanoma--a "rapidly fatal" form of cancer--journalist and mother of two Mary Elizabeth Williams finds herself in a race against the clock. She takes a once-in-a-lifetime chance and joins a clinical trial for immunotherapy, a revolutionary drug regimen that trains the body to vanquish malignant cells. Astonishingly, her cancer disappears entirely in just a few weeks. But at the same time, her best friend embarks on a cancer journey of her own--with very different results. Williams's experiences as a patient and a medical test subject reveal with stark honesty what it takes to weather disease, the extraordinary new developments that are rewriting the rules of science--and the healing power of human connection.

"After being diagnosed in her early 40s with metastatic melanoma--a 'rapidly fatal' form of cancer--journalist and mother of two Mary Elizabeth Williams finds herself in a race against the clock. She takes a once-in-a-lifetime chance and joins a clinical trial for immunotherapy, a revolutionary drug regimen that trains the body to vanquish malignant cells. Astonishingly, her cancer disappears entirely in just a few weeks. But at the same time, her best friend embarks on a cancer journey of her own--with very different results"--

The landmark work on mindfulness, meditation, and healing, now revised and updated after twenty-five years Stress. It can sap our energy, undermine our health if we let it, even shorten our lives. It makes us more vulnerable to anxiety and depression, disconnection and disease. Based on Jon Kabat-Zinn’s renowned mindfulness-based stress reduction program, this classic, groundbreaking work—which gave rise to a whole new field in medicine and psychology—shows you how to use medically proven mind-body approaches derived from meditation and yoga to counteract stress, establish greater balance of body and mind, and stimulate well-being and healing. By engaging in these mindfulness practices and integrating them into your life from moment to moment and from day to day, you can learn to manage chronic pain, promote optimal healing, reduce anxiety and feelings of panic, and improve the overall quality of your life, relationships, and social networks. This second edition features results from recent studies on the science of mindfulness, a new Introduction, up-to-date statistics, and an extensive updated reading list. Full Catastrophe Living is a book for the young and the old, the well and the ill, and anyone trying to live a healthier and saner life in our fast-paced world. Praise for Full Catastrophe Living “To say that this wise, deep book is helpful to those who face the challenges of human crisis would be a vast understatement. It is essential, unique, and, above all, fundamentally healing.”—Donald M. Berwick, M.D., president emeritus and senior fellow, Institute for Healthcare Improvement “One of the great classics of mind/body medicine.”—Rachel Naomi Remen, M.D., author of Kitchen Table Wisdom “A book for everyone . . . Jon Kabat-Zinn has done more than any other person on the planet to spread the power of mindfulness to the lives of ordinary people and major societal institutions.”—Richard J. Davidson, founder and chair, Center for Investigating Healthy Minds, University of Wisconsin–Madison “This is the ultimate owner’s manual for our lives. What a gift!”—Amy Gross, former editor in chief, O: The Oprah Magazine “I first read Full Catastrophe Living in my early twenties and it changed my life.”—Chade-Meng Tan, Jolly Good Fellow of Google and author of Search Inside Yourself “Jon Kabat-Zinn’s classic work on the practice of mindfulness to alleviate stress and human suffering stands the test of time, a most useful resource and practical guide. I recommend this new edition enthusiastically to doctors, patients, and anyone interested in learning to use the power of focused awareness to meet life’s challenges, whether great or small.”—Andrew Weil, M.D., author of Spontaneous Happiness and 8 Weeks to Optimum Health “How wonderful to have a new and updated version of this classic book that invited so many of us down a path that transformed our minds and awakened us to the beauty of each moment, day-by-day, through our lives. This second edition, building on the first, is sure to become a treasured sourcebook and traveling companion for new generations who seek the wisdom to live full and fulfilling lives.”—Diana Chapman Walsh, Ph.D., president emerita of Wellesley College

From President Bill Clinton's recommended reading list Publishers Weekly Bestseller Warnings is the story of the future of national security, threatening technologies, the U.S. economy, and possibly the fate of civilization. In Greek mythology Cassandra foresaw calamities, but was cursed by the gods to be ignored. Modern-day Cassandras clearly predicted the disasters of Katrina, Fukushima, the Great Recession, the rise of ISIS, the spread of viruses and many more. Like the mythological Cassandra, they were ignored. There are others right now warning of impending disasters—from cyber attacks to pandemics—but how do we know which warnings are likely to be right? Through riveting explorations in a variety of fields, the authors—both accomplished CEOs and White House National Security Council veterans—discover a method to separate the accurate Cassandras from the crazy doomsayers. They then investigate the experts who today are warning of future disasters: the threats from artificial intelligence, bio-hacking, malware attacks, and more, and whose calls are not being heeded. Clarke’s and Eddy’s penetrating insights are essential for any person, any business, or any government that doesn’t want to be a blind victim of tomorrow’s catastrophe.