Studies on humans have saved countless lives, but sometimes harm participants. Research ethics committees currently monitor scientists, but have been increasingly criticized for blocking important research. How these committees work, however, is largely unknown. This book uniquely illuminates this hidden world that ultimately affects us all.

The Oxford Textbook of Clinical Research Ethics is the first comprehensive and systematic reference on clinical research ethics. Under the editorship of experts from the U.S. National Institutes of Health of the United States, the book's 73 chapters offer a wide-ranging and systematic examination of all aspects of research with human beings. Considering the historical triumphs of research as well as its tragedies, the textbook provides a framework for analyzing the ethical aspects of research studies with human beings. Through both conceptual analysis and systematic reviews of empirical data, the contributors examine issues ranging from scientific validity, fair subject selection, risk benefit ratio, independent review, and informed consent to focused consideration of international research ethics, conflicts of interests, and other aspects of responsible conduct of research. The editors of The Oxford Textbook of Clinical Research Ethics offer a work that critically assesses and advances scholarship in the field of human subjects research. Comprehensive in scope and depth, this book will be a crucial resource for researchers in the medical sciences, as well as teachers and students.

James Charlton has produced a ringing indictment of disability oppression, which, he says, is rooted in degradation, dependency, and powerlessness and is experienced in some form by five hundred million persons throughout the world who have physical, sensory, cognitive, or developmental disabilities. Nothing About Us Without Us is the first book in the literature on disability to provide a theoretical overview of disability oppression that shows its similarities to, and differences from, racism, sexism, and colonialism. Charlton's analysis is illuminated by interviews he conducted over a ten-year period with disability rights activists throughout the Third World, Europe, and the United States. Charlton finds an antidote for dependency and powerlessness in the resistance to disability oppression that is emerging worldwide. His interviews contain striking stories of self-reliance and empowerment evoking the new consciousness of disability rights activists. As a latecomer among the world's liberation movements, the disability rights movement will gain visibility and momentum from Charlton's elucidation of its history and its political philosophy of self-determination, which is captured in the title of his book. Nothing About Us Without Us expresses the conviction of people with disabilities that they know what is best for them. Charlton's combination of personal involvement and theoretical awareness assures greater understanding of the disability rights movement.

Pity, disgust, fear, cure, and prevention--all are words that Americans have used to make sense of what today we call intellectual disability. Inventing the Feeble Mind explores the history of this disability from its several identifications over the past 200 years: idiocy, imbecility, feeblemindedness, mental defect, mental deficiency, mental retardation, and most recently intellectual disability. Using institutional records, private correspondence, personal memories, and rare photographs, James Trent argues that the economic vulnerability of intellectually disabled people (and often their families), more than the claims made for their intellectual and social limitations, has shaped meaning, services, and policies in United States history.

This alternative guidebook for one of the world’s most popular tourist destinations explores all five boroughs to reveal a people’s New York City. The sites and stories of A People’s Guide to New York City shift our perception of what defines New York, placing the passion, determination, defeats, and victories of its people at the core. Delving into the histories of New York's five boroughs, you will encounter enslaved Africans in revolt, women marching for equality, workers on strike, musicians and performers claiming streets for their art, and neighbors organizing against landfills and industrial toxins and in support of affordable housing and public schools. The streetscapes that emerge from these groups' struggles bear the traces, and this book shows you where to look to find them. New York City is a preeminent global city, serving as the headquarters for hundreds of multinational firms and a world-renowned cultural hub for fashion, art, and music. It is among the most multicultural cities in the world and also one of the most segregated cities in the United States. The people that make this global city function—immigrants, people of color, and the working classes—reside largely in the so-called outer boroughs, outside the corporations, neon, and skyscrapers of Manhattan. A People’s Guide to New York City expands the scope and scale of traditional guidebooks, providing an equitable exploration of the diverse communities throughout the city. Through the stories of over 150 sites across the Bronx, Manhattan, Queens, Brooklyn and Staten Island as well as thematic tours and contemporary and archival photographs, a people’s New York emerges, one in which collective struggles for justice and freedom have shaped the very landscape of the city.

"Discusses the hundreds of murders that occur in Los Angeles each year, and focuses on the story of the dedicated group of detectives who pursued justice at any cost in the killing of Bryant Tennelle"--Publisher's description.

The Willowbrook Wars is a dramatic and illuminating account of the effort to close down a scandal-ridden institution and return its 5,400 handicapped residents to communities in New York. The wars began in 1972 with Geraldo Rivera's televised raid on the Willowbrook State School. They continued for three years in a federal courtroom, with civil libertarian lawyers persuading a conservative and conscience-stricken judge to expand the rights of the disabled, and they culminated in a 1975 consent decree, with the state of New York pledging to accomplish the unprecedented assignment in six years. From 1975 to 1982, David and Sheila Rothman observed this remarkable chapter in American reform of mental disabilities care. Would the state live up to its agreement without "dumping" residents into other nightmarish institutions? Would the lawyers prove as interested in meeting client needs as in securing client rights? Could a tradition-bound bureaucracy create a new network of community services? And finally, would a governor and a legislature tolerate such outside intervention, and if so, for how long? In answering these questions, The Willowbrook Wars takes us behind the scenes to clarify the role of the judiciary, the fate of the underprivileged, and the potential for social justice. In their new afterword, the authors bring the story up to date, describing the results of the closing of the institution in 1987 from the experiences of integrating the former residents into communities to the legal battles between the state of New York and advocates for the mentally handicapped.

The Oxford Handbook of Disability History features twenty-seven articles that span the diverse, global history of the disabled--from antiquity to today.