This text, aimed at the clinical cardiologist, covers the planning of and partcipation in a clinical trial. It interprets the importance of past clinical trials in current clinical practice.

Landmark Papers in Cardiovascular Medicine provides a thorough and wide-ranging analysis of core examples of novel research, clinical trials and seminal papers that have paved the way for breakthroughs in the management of the entire spectrum of cardiovascular disease.

In November 1986, I was invited to attend a symposium held in Barcelona on Diseases of the Pericardium. The course was directed by Dr. J. Soler-Soler, director of Cardiology at Hospital General Vall d'Hebron in Barcelona. During my brief but delightful visit to this institution, my appreciation of the depth and breadth of study into pericardial diseases, carried out by Dr. Soler and his group, grew into the conviction that these clinical investigators have accumulated a wealth of information concerning pericardial diseases, and that investigators and clinicians practicing in English speaking countries would greatly profit from ready access to the results of the clinical investiga tions into pericardial disease carried out in Barcelona. The proceedings of the Barcelona conference were published in a beauti fully executed volume in the Spanish language edited by Dr. Soler and pro duced by Ediciones Doyma. Because I believe that this work should be brought to the attention of the English speaking scientific and clinical com munities, I encouraged Dr. Soler to have the book translated into English. I knew that this task could be accomplished and that the book would be trans lated into good English without change of its content. My confidence was based upon a translation of my own book, The Pericardium, into Spanish undertaken by Dr. Permanyer, who is a contributor and co-editor of the pre sent volume.

Few of the great stories of medicine are as palpably dramatic as the invention of open-heart surgery, yet, until now, no journalist has ever brought all of the thrilling specifics of this triumph to life. This is the story of the surgeon many call the father of open-heart surgery, Dr. C. Walton Lillehei, who, along with colleagues at University Hospital in Minneapolis and a small band of pioneers elsewhere, accomplished what many experts considered to be an impossible feat: He opened the heart, repaired fatal defects, and made the miraculous routine. Acclaimed author G. Wayne Miller draws on archival research and exclusive interviews with Lillehei and legendary pioneers such as Michael DeBakey and Christiaan Barnard, taking readers into the lives of these doctors and their patients as they progress toward their landmark achievement. In the tradition of works by Richard Rhodes and Tracy Kidder, King of Hearts tells the story of an important and gripping piece of forgotten science history.

Multiple choice question-and-answer book for cardiologists at all levels, now updated to include 100 new questions covering additional topics Cardiology Board Review, Second Edition is a multiple-choice question-and-answer study aid that is written for the primary purpose of helping candidates prepare for the American Board of Internal Medicine (ABIM) subspecialty certification. The questions address all areas of cardiology, some of which include: physical examination, ECG section with high resolution images, non-invasive and invasive imaging, myocardial diseases, and more. Each of the 1,400 questions is followed by four answers to choose from and the discussions address not only the rationale behind picking the right choice, but also fills in information around the topic so that important key concepts are clearly laid out. This helps candidates to prepare for the test, while also developing a clear understanding of various aspects of cardiology, including diagnosis and management. Written by two highly experienced authors in the field of healthcare, Cardiology Board Review, Second Edition covers topics such as: History and physical examinations, electrocardiography, chest x-rays in cardiology, stress testing and risk stratification of asymptomatic subjects, and echocardiography Cardiac magnetic resonance imaging, cardiac computed tomography, cardiac catheterization, acute coronary syndromes, and chronic coronary artery disease Heart failure, transplant, left ventricular assist devices, pulmonary hypertension, cardiomyopathies, hypertension, and diabetes mellitus Lipids, valvular heart disease, adult congenital heart disease, pericardial diseases, aortic diseases, and cardiac arrhythmias Pacemakers and defibrillators, cardiac masses, systemic disorders affecting the heart, and heart disease and pregnancy Providing comprehensive coverage of all relevant subjects and offering the easy-to-understand "why" behind the answer to each question, this second edition of Cardiology Board Review is an essential study resource for fellows in training, practicing cardiologists, and those preparing for ABIM subspecialty board in cardiology.

This book is open access under a CC BY 4.0 license. This quick-reference handbook offers a concise and practical review of key aspects of the treatment of ST-segment elevation myocardial infarction (STEMI) in the era of primary percutaneous coronary intervention (PPCI). In the context of STEMI, PPCI is the preferred mode of emergency revascularization. Access to PPCI is rapidly increasing and is now routinely practiced in both general and specialist hospitals and there has been a recent emphasis on developing STEMI networks to enhance and expedite the referral pathway. This coupled with concurrent developments to enhance the safety and efficacy of the PPCI procedure has heralded an era where STEMI interventions are increasingly considered an important subspecialty within interventional cardiology. Written by leading cardiologists who have been instrumental in the adoption of PPCI in their respective institutions, the book provides junior and senior cardiologists alike with insightful and thought-provoking tips and tricks to enhance the success of PPCI procedures, which may in turn translate into direct improvements in outcomes. The book is also relevant for healthcare providers and emergency department physicians.

This second editionis a ground-breaking clinical text with a strong emphasis on rigorous evidence. Leaders in the field discuss best practice in the light of systematic reviews and randomised control trials, and how best to treat where the information is less clear. Case histories provide intriguing discussions on how to apply the evidence in real life situations. Evidence-based Cardiology also includes free access to the latest evidence, which is automatically posted on a companion website.

Ventricular arrhythmias cause most cases of sudden cardiac death, which is the leading cause of death in the US. This issue reviews the causes of arrhythmias and the promising new drugs and devices to treat arrhythmias.