The light sense is conceivably the key sense in both the animal and the plant kingdom. Vision research, undoubtedly a fast-growing field, is providing impressive results — thanks to modern theoretical and methodological advances. The approach of biophysics and neuroscience seems to be of great benefit and, for this reason, the present book gives an outline of recent acquisitions and updated advanced methods concerning this approach. Visual mechanisms and processes are analysed at several (molecular, cellular, integrative, computational and cognitive) levels by different methodologies (from molecular biology to computation) applied to different living models (from protists to humans, via invertebrates and lower vertebrates).

For a few decades, the puzzle of consciousness, which for centuries was analysed by philosophers, has been finding a wide interest in the scientific field, where previously it was not entitled to be a member. It has become one of the most-debated problems in the cognitive sciences. The anatomical bases, neurophysiological correlates and elementary mechanisms underlying complex processes arising with consciousness have been compared with the psychological (perceptive, cognitive, volitive, emotional) aspects of conscious expressions, in normal and pathological conditions. Various theories, which attempt to fit systematically and coherently neural and psychological data, have been debated, proving the emergence of the phenomenon of consciousness.

The light sense is conceivably the key sense in both the animal and the plant kingdom. Vision research, undoubtedly a fast-growing field, is providing impressive results ? thanks to modern theoretical and methodological advances. The approach of biophysics and neuroscience seems to be of great benefit and, for this reason, the present book gives an outline of recent acquisitions and updated advanced methods concerning this approach. Visual mechanisms and processes are analysed at several (molecular, cellular, integrative, computational and cognitive) levels by different methodologies (from molecular biology to computation) applied to different living models (from protists to humans, via invertebrates and lower vertebrates).

This volume is the record and product of the Summer School on the Physics and Mathematics of the Nervous System, held at the International Centre for Theoretical Physics in Trieste from August 21-31, 1973, and jointly organized by the Institute for Information Sciences, University of Tlibingen and by the Centre. The school served to bring biologists, physicists and mathemati cians together to exchange ideas about the nervous system and brain, and also to introduce young scientists to the field. The program, attended by more than a hundred scientists, was interdisciplinary both in character and participation. The primary support for the school was provided by the Volkswagen Foundation of West Germany. We are particularly indebted to Drs. G. Gambke, M. -L Zarnitz, and H. Penschuck of the Foundation for their in terest in and help with the project. The school also received major support from the International Centre for Theoretical Physics in Trieste and its sponsoring agencies, including the use of its excellent facili ties. We are deeply indebted to Professor A. Salam for his kind co operation and also to Professor P. Budini, Dr. A. M. Hamende, and to the many members of the Centre staff whose hospitality and efficiency con tributed so much to the success of the school. We are pleased to acknow ledge the generous ~id and cooperation of the University of Tlibingen and would like to thank its President, A.

Biophysics is a science that comprises theoretical plotting and models based on contemporary physicochemical conceptions. They mirror physical specificity of the molecular organization and elementary processes in living organisms, which in their turn form the molecular basis of biological phenomena. Presentation of a complete course in biophysics requires vast biological material as well as additional involvement of state-of-the-art concepts in physics, chemistry and mathematics. This is essential for the students to "perceive" the specific nature and peculiarity of molecular biological processes and see how this specificity is displayed in biological systems. This is the essence of the up-to-date biophysical approach to the analysis of biological processes. Fundamentals of Biophysics offers a complete, thorough coverage of the material in a straightforward and no-nonsense format, offering a new and unique approach to the material that presents the appropriate topics without extraneous and unneeded filler material.

An overview of recent experimental and theoretical developments in the field of the physics of membranes, including new insights from the past decade. The author uses classical thermal physics and physical chemistry to explain our current understanding of the membrane. He looks at domain and 'raft' formation, and discusses it in the context of thermal fluctuations that express themselves in heat capacity and elastic constants. Further topics are lipid-protein interactions, protein binding, and the effect of sterols and anesthetics. Many seemingly unrelated properties of membranes are shown to be intimately intertwined, leading for instance to a coupling between membrane state, domain formation and vesicular shape. This also applies to non-equilibrium phenomena like the propagation of density pulses during nerve activity. Also included is a discussion of the application of computer simulations on membranes. For both students and researchers of biophysics, biochemistry, physical chemistry, and soft matter physics.

A physicist's guide to the phenomena of life Interactions between the fields of physics and biology reach back over a century, and some of the most significant developments in biology—from the discovery of DNA's structure to imaging of the human brain—have involved collaboration across this disciplinary boundary. For a new generation of physicists, the phenomena of life pose exciting challenges to physics itself, and biophysics has emerged as an important subfield of this discipline. Here, William Bialek provides the first graduate-level introduction to biophysics aimed at physics students. Bialek begins by exploring how photon counting in vision offers important lessons about the opportunities for quantitative, physics-style experiments on diverse biological phenomena. He draws from these lessons three general physical principles—the importance of noise, the need to understand the extraordinary performance of living systems without appealing to finely tuned parameters, and the critical role of the representation and flow of information in the business of life. Bialek then applies these principles to a broad range of phenomena, including the control of gene expression, perception and memory, protein folding, the mechanics of the inner ear, the dynamics of biochemical reactions, and pattern formation in developing embryos. Featuring numerous problems and exercises throughout, Biophysics emphasizes the unifying power of abstract physical principles to motivate new and novel experiments on biological systems. Covers a range of biological phenomena from the physicist's perspective Features 200 problems Draws on statistical mechanics, quantum mechanics, and related mathematical concepts Includes an annotated bibliography and detailed appendixes

Most of the specialists working in this interdisciplinary field of physics, biology, biophysics and medicine are associated with "The International Institute of Biophysics" (IIB), in Neuss, Germany, where basic research and possibilities for applications are coordinated. The growth in this field is indicated by the increase in financial support, interest from the scientific community and frequency of publications. Audience: The scientists of IIB have presented the most essential background and applications of biophotonics in these lecture notes in biophysics, based on the summer school lectures by this group. This book is devoted to questions of elementary biophysics, as well as current developments and applications. It will be of interest to graduate and postgraduate students, life scientists, and the responsible officials of industries and governments looking for non-invasive methods of investigating biological tissues.