This book provides a comprehensive overview on Transcranial Direct Current Stimulation (tDCS) and the clinical applications of this promising technique. Separated into three parts, the book begins with basic principles, mechanisms and approaches of tDCS. This is followed by a step-by-step practicum, methodological considerations and ethics and professional conduct pertaining to this novel technique. Chapters are authored by renowned experts who also direct and plan tDCS educational events worldwide. Bridging the existing gap in instructional materials for tDCS while addressing growing interest in education in this field, professionals within a broad range of medical disciplines will find this text to be an invaluable guide.

This book presents the state of the art regarding the use of non-invasive brain stimulation (TMS and tDCS) in the research and treatment of neuropsychiatric disorders. The contributions, all of which were prepared by internationally recognized experts in the field, are divided into two main sections (for TMS and tDCS, respectively) across diagnoses, following an introductory section on the mechanisms of action and neurophysiological background. Neuropsychological perspectives and approaches are provided as well. The book is ultimately intended to offer a unique, integrated approach to the use of non-invasive brain stimulation across the clinical neurosciences, providing a comprehensive and updated perspective that will benefit psychiatrists, neurologists, clinical psychologists and neurophysiologists alike.

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Neuropsychiatric diseases, such as schizophrenia, Alzheimer's disease, and etc., represent a serious medical and socioeconomic problems. These diseases are often accompanied by impairments of cognitive function, e.g., abstract thinking, decision-making, attention, and several types of memory. Such deficits significantly disrupt quality of life and daily functioning of patients. Cognitive deficits in neuropsychiatric diseases are associated with alterations of brain morphology and function, and are often resistant to therapeutic interventions. In schizophrenia and related disorders, cognitive deficits are also defined as endophenotypes, i.e. measurable phenotypes linking these disaeses with discrete heritable and reproducible traits. This points to the importance of elucidating these endophenotypes in translational studies. Animal models may not mimic the full spectrum of clinical symptoms, but may act as analogies of particular behaviors or other pathological outcomes. They are useful to search for the etiology of particular psychiatric illnesses and novel therapeutics. Moreover, several behavioral tests to measure cognitive performance in rodents and other species have been implemented. The primary focus of the present topic is to provide up-to-date information on cognitive deficits of neuropsychiatric disorders, such as schizophrenia. This Research Topic also delineates future directions for translational studies aimed at developing novel treatments/interventions of cognitive disturbances.

Edited by an expert multidisciplinary team, Neuromodulation in Psychiatry is the first reference guide to address both invasive and non-invasive neuromodulation strategies used in psychiatry. Covers basic principles, technical aspects, clinical applications and ethical considerations Presents up-to-date evidence in comprehensive summaries suitable for all levels of experience Each technique is clearly explained along with its implications for real-world clinical practice Allows psychiatrists to make informed decisions regarding neuromodulation for their patients

Transcranial magnectic stimulation (TMS) is a neurological technique for inducing motor movement by direct magnetic stimulation of the brain's motor cortex-while the subject is awake and alert-to measure connectivity and excitability. It depends on the principle of mutual induction (discovered by Michael Faraday in 1831), whereby electrical energy can be converted into magnetic fields, and magnetic fields can be converted into electrical energy. The ability to measure the excitability of the motor cortex in important in neuropsychiatry for several reasons: 1) TMS may prove valuable as a diagnostic tool, because there is increasing evidence of altered motor cortex excitability in several neuropsychiatric disorders. 2) Stimulus parameters (especially stimulus intensity) must be adjusted to the patient's individual motor excitability in repetitive TMS (rTMS) treatment protocols. Therefore, the knowledge of how to measure motor cortex excitability is indispensable. 3) Evidence shows that various rTMS protocols can increase or decrease cortical excitability and thus can be used therapeutically to normalize altered excitability in neuropsychiatry diseases. How did TMS evolve into the techniques used today? How does it fit into the localization debate (the idea that physiological functions are organized into discrete brain regions), now reenergized by the advent of modern neuroimaging tools (PET, SPECT, and MRI)? How does it differ from ECT? For what disorders is TMS effective, and how is this effectiveness measured? What safety concerns are involved? Where is future research headed? For the answers to these questions, readers can now turn to a single source, "Transcranial MagneticStimulation in Neuropsychiatry," In these fascinating chapters rich with illustrations, current clinical researchers describe how-thanks to TMS-they now have elaborate roadmaps of the brain regions putatively involved in specific disorders including movement disorders, epilepsy, major depression, bipolar disorder/mania, anxiety disorders, developmental stuttering and Tourette's syndrome, and schizophrenia. Even with advances in neuroimaging science, much of the adult human brain remains a mystery. "Transcranial Magnetic Stimulation in Neuropsychiatry" helps shed light on the astonishing intricacies of brain function and organization, and as such is a must-read for anyone interested in how the brain works-clinical researchers of brain function, neuroscientists, neurologists, general psychiatrists, neuropsychiatrists, psychologists, and social workers.

This textbook, one of the first, provides a comprehensive review of the relationship between psychiatry and legal medicine in the older population. Sections reviewing evaluation, civil and criminal topics, and numerous other areas such as risk management, will help physicians, attorneys, and other professionals in their work with the elderly.

The Stimulated Brain—which garnered an Honorable Mention for Biomedicine & Neuroscience at the 2015 PROSE Awards from the Association of American Publishers—presents the first integration of findings on brain stimulation from different research fields with a primary focus on Transcranial Electrical Stimulation (tES), one of the most frequently used noninvasive stimulation methods. The last decade has witnessed a significant increase in the amount of research exploring how noninvasive brain stimulation can not only modulate but also enhance cognition and brain functions. However, although Transcranial Magnetic Stimulation (TMS) and particularly tES have the potential to become more widely applicable techniques (as they come with none of the risks associated with deep brain stimulation) the reference literature on these neurotechnologies has been sparse. This resource provides a broad survey of current knowledge, and also marks future directions in cognitive and neuro-enhancement. It expands our understanding of basic research findings from animals and humans, including clear translational benefits for applied research and the therapeutic use of noninvasive brain stimulation methods. The book's coverage includes a primer that paves the way to a more advanced knowledge of tES and its physiological basis; current research findings on cognitive and neuro-enhancement in animals and typical and atypical human populations, such as neurological patients; and discussions of future directions, including specific neuroethical issues and pathways for collaboration and entrepreneurialism. The Stimulated Brain is the first book to provide a comprehensive understanding of different aspects of noninvasive brain stimulation that are critical for scientists, clinicians, and those who are interested in "stimulating their minds by exploring this fascinating field of research. - Honorable Mention for Biomedicine & Neuroscience in the 2015 PROSE Awards from the Association of American Publishers - The only reference on the market to focus on transcranial electrical stimulation (tES) - Coverage across technical, historical, and application topics makes this the single, comprehensive resource for researchers and students - Edited book with chapters authored by international leaders in the fields of medicine, neuroscience, psychology, and philosophy—providing the broadest, most expert coverage available

Brain stimulation technologies are both tools to probe brain function and to provide therapeutic options for patients with neuropsychiatric disease where pharmacological options are not viable. Although the field has been in existence for over seventy years, research interest in brain stimulation has been on the rise particularly in the last two decades. Brain Stimulation: Methodologies and Interventions is an introduction to the field of brain stimulation technology and its applications. The book explores how brainstimulating technologies work in the context of brain pathways that mediate normal and abnormal brain function. Chapters cover neuroanatomy and activity dependent changes in neuronal function triggered by brain stimulation, as well as applications of brain stimulation technologies themselves, including noninvasive procedures that rely on convulsive or seizure therapeutics, and non-convulsive therapies such as magnetic and electrical brain stimulation. Authored by an international group of leaders in the field, Brain Stimulation is a valuable resource for both neuroscience researchers and clinicians.