"Update of: Trichiasis surgery for trachoma, the bilamellar tarsal rotation procedure and 'Final assessment of trichiasis surgeons."

Presents a fascinating and comprehensive review of trachoma, from ancient times through to the present. He makes his own predictions and recommendations regarding methods for eliminating this scourge for all time. Trachoma, which has been targeted by the World Health Organization (WHO) for elimination by 2020, currently affects 84 million children in 56 countries and blinds 1.5 million adults. This seminal and highly readable work will be invaluable for anyone who is interested in trachoma, but will also appeal to those interested in the interface of public health and development, the history of medicine or health care development.

The Middle East and North Africa (MENA) is highly endemic for several neglected tropical diseases (NTDs), including viral, bacterial, protozoan and helminth infections. This new volume covers the most prevalent NTDs found in about 22 MENA countries emphasizing the disease burden, clinical manifestations and control approaches. Each individual chapter deals with one specific disease and is written by a group of experts on that topic.

Medicinal Spices and Vegetables from Africa: Therapeutic Potential against Metabolic, Inflammatory, Infectious and Systemic Diseases provides a detailed look at medicinal spices and vegetables that have proven safe-and-effective for consumption and the treatment of diseases, including infectious diseases, cardiovascular disease, and cancer. It provides pharmacological evidence, such as the latest information related to efficacy and safety data, in vitro and in vivo studies, clinical trials, and more, to illustrate the use of these spices and vegetables as both palliative and alternative treatments with the goal of furthering research in this area to produce safer and more effective drugs. - Provides scientific evidence for the potential of medicinal spices and vegetables used in Africa to fight metabolic, inflammatory, and infectious diseases - Includes a review of the latest methods used to investigate the effects of medicinal plants in the treatment of disease - Offers an updated resource for students sand scientists in the fields of pharmaceutical science, pharmacognosy, complementary and alternative medicine, ethnopharmacology, phytochemistry, biochemistry, and more

This volume is the first book-length treatment of model-based geostatistics. The text is expository, emphasizing statistical methods and applications rather than the underlying mathematical theory. Analyses of datasets from a range of scientific contexts feature prominently, and simulations are used to illustrate theoretical results. Readers can reproduce most of the computational results in the book by using the authors' software package, geoR, whose usage is illustrated in a computation section at the end of each chapter. The book assumes a working knowledge of classical and Bayesian methods of inference, linear models, and generalized linear models.

Trachoma is an infectious eye disease that causes blindness; it is prevalent in many poor rural communities. The World Health Organization has set the year 2020 as the target for global elimination of trachoma as a public health problem. To reach this target, the SAFE strategy (Surgery for trichiasis Antibiotics to treat Chlamydia trachomatis infection, and Facial cleanliness and Environmental improvement to reduce transmission of C. trachomatis from one person to another) is recommended for districts and communities with endemic disease. This guide has been written for managers of national and district trachoma control programs. It sets out, step-by-step, what is needed to assess the magnitude and extent of the trachoma problem in the area and how to plan, implement, monitor, and evaluate a program to control, and ultimately eliminate trachoma. Templates for a number of forms recommended for use in a program can be found in the annex. To allow adaptation of the forms for use in a specific program, electronic versions are available on the CD-ROM that accompanies this guide. The CD-ROM also contains an antibiotic requirement estimator, a template budget and a generic evaluation manual. Two versions of this guide are available:The trainer s version includes the guide with a set of 30 slides and the CD-ROM. The learner's version contains the guide with the CD-ROM.

"Essentials in Ophthalmology" is a new review series covering all of ophthalmology categorized in eight subspecialties. It will be published quarterly, thus each subspecialty will be reviewed biannually. Given the multiplicity of medical publications already available, why is a new series needed? Consider that the half-life of medical knowledge is estimated to be around 5 years. Moreover, it can be as long as 8 years between the first description of a medical innovation in a peer-reviewed scientific journal and publication in a medical textbook. A series that narrows this time span between journal and textbook would provide a more rapid and efficient transfer of medical knowledge into clinical practice, and enhance care of our patients.

The purpose of the guideline was to provide an evidence-informed recommendation on whether mass drug administration of azithromycin, as a public health intervention for the reduction of under-five mortality, should (a) be rolled out universally in low- and middle-income countries, (b) be applied only in some situational contexts in low-and middle-income countries or (c) not be used at all.

New insights into one of the world's most common infectious diseases Chlamydiae are obligate intracellular bacteria that cause one of the most common sexually transmitted infectious diseases in the world. The infection disproportionately impacts women and the highest prevalence of infection is found in adolescents. Most chlamydial infections are asymptomatic. Untreated infections are sources of further spread of infection and can lead to serious consequences including pelvic inflammatory disease, infertility and chronic pelvic pain. Chlamydial infections also increase a person's susceptibility to HIV and other STDs. Featuring contributions by internationally recognized experts in epidemiology, infectious disease research and chlamydial biology, this book provides up-to-date reviews from a clinical and public health perspective on chlamydia epidemiology and control programs, genomics and pathogenicity, diagnosis, treatment, host immune responses, and the latest on the search for an effective vaccine. Also included are chapters on the impact of chlamydial infection on specific populations such as the lesbian, gay, bisexual and transgender community, and an update on the outbreak in Europe of the invasive chlamydial infection, lymphogranuloma venereum or LGV. This comprehensive publication is intended for clinicians, public health workers and scientists with interest in sexually transmitted diseases, medical microbiology, infectious diseases and clinical research.