"With one glance, Dr. DeRienzo creates a human connection with his patients and reminds us that we need to build trust, value the sacred relationship between a doctor and a patient, and restore the patient voice and narrative back to healthcare. He gives the reader hope that healthcare can be healed." - Dr. Bridget DuffyImagine holding a baby girl's life in your hands - now imagine she's no bigger than a soda can. Every year, nearly 4 million babies are born in the United States. Most arrive safely and go home with their families in a matter of days. But not all babies come into the world healthy and almost half a million arrive well before they are expected. These newborns need tiny medicine. Told from the first-person perspective, Dr. Chris DeRienzo walks readers through the human experience of caring for the world's smallest and sickest patients. Readers will learn the secrets of the NICU, the loneliness that comes with life and death decisions, and the incredibly powerful sense of purpose and triumph that comes with just making it through the night and keeping everyone alive. In the end, this book delivers an insider's view of what it's really like to serve the world's tiniest humans."Tiny Medicine offers a rare, behind-the-scenes, look into the life and work of one of our nation's leading neonatologists, Dr. Chris DeRienzo. Full of compelling stories, humor, and raw emotional vulnerability, DeRienzo takes us on a journey through the joys and tragedies of caring for the smallest patients, often in life or death situations." - Nate Klemp, PhD, New York Times Best-Selling author

The life story of Vivien Thomas, an African American surgical technician who developed the first procedure used to perform open-heart surgery on children.

"When bacteria and viruses attack"--Cover.

A thrilling story of scientific detective work and medical potential that illuminates the newly understood role of microglia—an elusive type of brain cell that is vitally relevant to our everyday lives. “The rarest of books: a combination of page-turning discovery and remarkably readable science journalism.”—Mark Hyman, MD, #1 New York Times bestselling author of Food: What the Heck Should I Eat? NAMED ONE OF THE BEST BOOKS OF THE YEAR BY WIRED Until recently, microglia were thought to be helpful but rather boring: housekeeper cells in the brain. But a recent groundbreaking discovery has revealed that they connect our physical and mental health in surprising ways. When triggered—and anything that stirs up the immune system in the body can activate microglia, including chronic stressors, trauma, and viral infections—they can contribute to memory problems, anxiety, depression, and Alzheimer’s. Under the right circumstances, however, microglia can be coaxed back into being angelic healers, able to make brain repairs in ways that help alleviate symptoms and hold the promise to one day prevent disease. With the compassion born of her own experience, award-winning journalist Donna Jackson Nakazawa illuminates this newly understood science, following practitioners and patients on the front lines of treatments that help to “reboot” microglia. In at least one case, she witnesses a stunning recovery—and in others, significant relief from pressing symptoms, offering new hope to the tens of millions who suffer from mental, cognitive, and physical health issues. Hailed as a “riveting,” “stunning,” and “visionary,” The Angel and the Assassin offers us a radically reconceived picture of human health and promises to change everything we thought we knew about how to heal ourselves.

History of the breakthrough of the cancer pill "Gleevec."

A captivating blend of history, women in science, and true crime, 18 Tiny Deaths tells the story of how one woman changed the face of forensics forever. Frances Glessner Lee, born a socialite to a wealthy and influential Chicago family in the 1870s, was never meant to have a career, let alone one steeped in death and depravity. Yet she developed a fascination with the investigation of violent crimes, and made it her life's work. Best known for creating the Nutshell Studies of Unexplained Death, a series of dollhouses that appear charming—until you notice the macabre little details: an overturned chair, or a blood-spattered comforter. And then, of course, there are the bodies—splayed out on the floor, draped over chairs—clothed in garments that Lee lovingly knit with sewing pins. 18 Tiny Deaths, by official biographer Bruce Goldfarb, delves into Lee's journey from grandmother without a college degree to leading the scientific investigation of unexpected death out of the dark confines of centuries-old techniques and into the light of the modern day. Lee developed a system that used the Nutshells dioramas to train law enforcement officers to investigate violent crimes, and her methods are still used today. The story of a woman whose ambition and accomplishments far exceeded the expectations of her time, 18 Tiny Deaths follows the transformation of a young, wealthy socialite into the mother of modern forensics... "Eye-opening biography of Frances Glessner Lee, who brought American medical forensics into the scientific age...genuinely compelling."—Kirkus Reviews "A captivating portrait of a feminist hero and forensic pioneer." —Booklist

Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.

Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine—and how understanding these principles can empower us all. Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a “science”? Sciences must have laws—statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences? Dr. Mukherjee has spent his career pondering this question—a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline—culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine. Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee’s signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.

Prepared by residents and attending physicians at Massachusetts General Hospital, this pocket-sized looseleaf is one of the best-selling references for medical students, interns, and residents on the wards and candidates reviewing for internal medicine board exams. In bulleted lists, tables, and algorithms, Pocket Medicine provides key clinical information about common problems in internal medicine, cardiology, pulmonary medicine, gastroenterology, nephrology, hematology-oncology, infectious diseases, endocrinology, and rheumatology. This Fifth Edition is fully updated and includes a sixteen-page color insert with key and classic abnormal images. If you purchased a copy of Sabatine: Pocket Medicine 5e, ISBN 978-1-4511-8237-8, please make note of the following important correction on page 1-36: Oral anticoagulation ( Chest 2012;141: e531S; EHJ 2012;33:2719; Circ 2013;127:1916)- All valvular AF as stroke risk very high- Nonvalv. AF: stroke risk 4.5%/y; anticoag (R) 68% ̄ stroke; use a risk score to guide Rx: CHADS2: CHF (1 point), HTN (1), A ge >= 75 y (1), DM (1), prior Stroke/TIA (2)CHA2DS2-VASc: adds 65-74 y (1) >=75 y (2), vasc dis. [MI, Ao plaque, or PAD (1)]; ? (1)score 32 (R) anticoag; score 1 (R) consider anticoag or ASA (? latter reasonable if risk factor age 65-74 y, vasc dis. or ?); antithrombotic Rx even if rhythm control [SCORE CORRECTED]- Rx options: factor Xa or direct thrombin inhib (non-valv only; no monitoring required) or warfarin (INR 2-3; w/ UFH bridge if high risk of stroke); if Pt refuses anticoag, considerASA + clopi or, even less effective, ASA alone ( NEJM 2009;360:2066)Please make note of this correction in your copy of Sabatine: Pocket Medicine 5e immediately and contact LWW's Customer Service Department at 1.800.638.3030 or 1.301.223.2300 so that you may be issued a corrected page 1-36. You may also download a PDF of page 1-36 by clicking HERE. All copies of Pocket Medicine, 5e with the ISBN: 978-1-4511-9378-7 include this correction.