The State Of Alzheimers Research
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Author |
: United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions. Subcommittee on Retirement and Aging |
Publisher |
: |
Total Pages |
: 56 |
Release |
: 2008 |
ISBN-10 |
: STANFORD:36105050475073 |
ISBN-13 |
: |
Rating |
: 4/5 (73 Downloads) |
Synopsis The State of Alzheimer's Research by : United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions. Subcommittee on Retirement and Aging
Author |
: Han Yu |
Publisher |
: Columbia University Press |
Total Pages |
: 487 |
Release |
: 2021-03-02 |
ISBN-10 |
: 9780231552769 |
ISBN-13 |
: 0231552769 |
Rating |
: 4/5 (69 Downloads) |
Synopsis Mind Thief by : Han Yu
Alzheimer’s disease, a haunting and harrowing ailment, is one of the world’s most common causes of death. Alzheimer’s lingers for years, with patients’ outward appearance unaffected while their cognitive functions fade away. Patients lose the ability to work and live independently, to remember and recognize. There is still no proven way to treat Alzheimer’s because its causes remain unknown. Mind Thief is a comprehensive and engaging history of Alzheimer’s that demystifies efforts to understand the disease. Beginning with the discovery of “presenile dementia” in the early twentieth century, Han Yu examines over a century of research and controversy. She presents the leading hypotheses for what causes Alzheimer’s; discusses each hypothesis’s tangled origins, merits, and gaps; and details their successes and failures. Yu synthesizes a vast amount of medical literature, historical studies, and media interviews, telling the gripping stories of researchers’ struggles while situating science in its historical, social, and cultural contexts. Her chronicling of the trajectory of Alzheimer’s research deftly balances rich scientific detail with attention to the wider implications. In narrating the attempts to find a treatment, Yu also offers a critical account of research and drug development and a consideration of the philosophy of aging. Wide-ranging and accessible, Mind Thief is an important book for all readers interested in the challenge of Alzheimer’s.
Author |
: Jeffrey Cummings |
Publisher |
: Cambridge University Press |
Total Pages |
: 575 |
Release |
: 2022-03-31 |
ISBN-10 |
: 9781108838665 |
ISBN-13 |
: 1108838669 |
Rating |
: 4/5 (65 Downloads) |
Synopsis Alzheimer's Disease Drug Development by : Jeffrey Cummings
Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.
Author |
: |
Publisher |
: Academic Press |
Total Pages |
: 399 |
Release |
: 2012-07-24 |
ISBN-10 |
: 9780123948458 |
ISBN-13 |
: 0123948452 |
Rating |
: 4/5 (58 Downloads) |
Synopsis Current State of Alzheimer's Disease Research and Therapeutics by :
This new volume of Advances in Pharmacology explores the Current State of Alzheimer's Disease Research and Therapeutics. Chapters cover such topics as the The role heat shock proteins play in the Alzheimer's Theater, Gamma-Secretase as a Target for Alzheimer's Disease, and Identification of protein kinase C for the treatment of dementias. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike. - Explores the current state of Alzheimer's disease research and therapeutics - Chapters cover a variety of topics such as the role heat shock proteins play in the Alzheimer's theater, gamma-secretase as a target for Alzheimer's disease, and identification of protein kinase C for the treatment of dementias - With the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike
Author |
: Jason Karlawish |
Publisher |
: St. Martin's Press |
Total Pages |
: 269 |
Release |
: 2021-02-23 |
ISBN-10 |
: 9781250218742 |
ISBN-13 |
: 1250218748 |
Rating |
: 4/5 (42 Downloads) |
Synopsis The Problem of Alzheimer's by : Jason Karlawish
A definitive and compelling book on one of today's most prevalent illnesses. In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. 16 million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their seventies and eighties, the number of patients will rise to an estimated 13.8 million by 2050. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis. While it is an unambiguous account of decades of missed opportunities and our health care systems’ failures to take action, it tells the story of the biomedical breakthroughs that may allow Alzheimer’s to finally be prevented and treated by medicine and also presents an argument for how we can live with dementia: the ways patients can reclaim their autonomy and redefine their sense of self, how families can support their loved ones, and the innovative reforms we can make as a society that would give caregivers and patients better quality of life. Rich in science, history, and characters, The Problem of Alzheimer's takes us inside laboratories, patients' homes, caregivers’ support groups, progressive care communities, and Jason Karlawish's own practice at the Penn Memory Center.
Author |
: National Academies of Sciences Engineering and Medicine |
Publisher |
: |
Total Pages |
: |
Release |
: 2022-04-26 |
ISBN-10 |
: 0309495032 |
ISBN-13 |
: 9780309495035 |
Rating |
: 4/5 (32 Downloads) |
Synopsis Reducing the Impact of Dementia in America by : National Academies of Sciences Engineering and Medicine
As the largest generation in U.S. history - the population born in the two decades immediately following World War II - enters the age of risk for cognitive impairment, growing numbers of people will experience dementia (including Alzheimer's disease and related dementias). By one estimate, nearly 14 million people in the United States will be living with dementia by 2060. Like other hardships, the experience of living with dementia can bring unexpected moments of intimacy, growth, and compassion, but these diseases also affect people's capacity to work and carry out other activities and alter their relationships with loved ones, friends, and coworkers. Those who live with and care for individuals experiencing these diseases face challenges that include physical and emotional stress, difficult changes and losses in their relationships with life partners, loss of income, and interrupted connections to other activities and friends. From a societal perspective, these diseases place substantial demands on communities and on the institutions and government entities that support people living with dementia and their families, including the health care system, the providers of direct care, and others. Nevertheless, research in the social and behavioral sciences points to possibilities for preventing or slowing the development of dementia and for substantially reducing its social and economic impacts. At the request of the National Institute on Aging of the U.S. Department of Health and Human Services, Reducing the Impact of Dementia in America assesses the contributions of research in the social and behavioral sciences and identifies a research agenda for the coming decade. This report offers a blueprint for the next decade of behavioral and social science research to reduce the negative impact of dementia for America's diverse population. Reducing the Impact of Dementia in America calls for research that addresses the causes and solutions for disparities in both developing dementia and receiving adequate treatment and support. It calls for research that sets goals meaningful not just for scientists but for people living with dementia and those who support them as well. By 2030, an estimated 8.5 million Americans will have Alzheimer's disease and many more will have other forms of dementia. Through identifying priorities social and behavioral science research and recommending ways in which they can be pursued in a coordinated fashion, Reducing the Impact of Dementia in America will help produce research that improves the lives of all those affected by dementia.
Author |
: United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions. Subcommittee on Aging |
Publisher |
: |
Total Pages |
: 48 |
Release |
: 2002 |
ISBN-10 |
: PURD:32754074744503 |
ISBN-13 |
: |
Rating |
: 4/5 (03 Downloads) |
Synopsis Alzheimer's Research and Care by : United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions. Subcommittee on Aging
Author |
: United States. Congress. House. Select Committee on Aging. Subcommittee on Human Services |
Publisher |
: |
Total Pages |
: 100 |
Release |
: 1983 |
ISBN-10 |
: UFL:31262045978086 |
ISBN-13 |
: |
Rating |
: 4/5 (86 Downloads) |
Synopsis Alzheimer's Disease by : United States. Congress. House. Select Committee on Aging. Subcommittee on Human Services
Author |
: Illana Gozes |
Publisher |
: Academic Press |
Total Pages |
: 344 |
Release |
: 2016-12-30 |
ISBN-10 |
: 9780128037126 |
ISBN-13 |
: 0128037121 |
Rating |
: 4/5 (26 Downloads) |
Synopsis Neuroprotection in Alzheimer's Disease by : Illana Gozes
Neuroprotection in Alzheimer’s Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together the latest findings, both basic, and clinical, under the same cover, making it easy for the reader to obtain a complete overview of the state-of-the-field and beyond. Alzheimer's disease is the most common form of dementia, accounting for 60 to 80 percent of dementia cases. It is a progressive brain disease that slowly destroys memory, thinking skills, and eventually, even the ability to carry out the simplest tasks. It is characterized by death of synapses coupled to death nerve cells and brain degeneration which is manifested by loss of cognitive abilities. Understanding neuroprotection in Alzheimer’s disease will pave the path to better disease management and novel therapeutics. Comprehensive reference detailing neuroprotection in Alzheimer’s Disease, with details on nerve cell protection and new advances in disease management Combines the knowledge and points-of-view of both medical doctors and basic scientists, putting the subject at the forefront for further clinical development Edited by one of the leading researchers in Alzheimer’s Disease
Author |
: United States. Congress. Senate. Committee on Appropriations. Subcommittee on Departments of Labor, Health and Human Services, Education, and Related Agencies |
Publisher |
: |
Total Pages |
: 44 |
Release |
: 2004 |
ISBN-10 |
: UCAL:B5107209 |
ISBN-13 |
: |
Rating |
: 4/5 (09 Downloads) |
Synopsis Alzheimer's Disease Research by : United States. Congress. Senate. Committee on Appropriations. Subcommittee on Departments of Labor, Health and Human Services, Education, and Related Agencies