This volume describes the current state of our knowledge on the neurobiology of muscle fatigue, with consideration also given to selected integrative cardiorespiratory mechanisms. Our charge to the authors of the various chapters was twofold: to provide a systematic review of the topic that could serve as a balanced reference text for practicing health-care professionals, teaching faculty, and pre-and postdoctoral trainees in the biomedi cal sciences; and to stimulate further experimental and theoretical work on neurobiology. Key issues are addressed in nine interrelated areas: fatigue of single muscle fibers, fatigue at the neuromuscular junction, fatigue of single motor units, metabolic fatigue studied with nuclear magnetic resonance, fatigue of the segmental motor system, fatigue involving suprasegmental mechanisms, the task dependency of fatigue mechanisms, integrative (largely cardiorespiratory) systems issues, and fatigue of adapted systems (due to aging, under-and overuse, and pathophysiology). The product is a volume that provides compre of processes that operate from the forebrain to the contractile proteins.

Fatigue can have a major impact on an individual's performance and well-being, yet is poorly understood, even within the scientific community. There is no developed theory of its origins or functions, and different types of fatigue (mental, physical, sleepiness) are routinely confused. The widespread interpretation of fatigue as a negative consequence of work may be true only for externally imposed goals; meaningful or self-initiated work is rarely tiring and often invigorating. In the first book dedicated to the systematic treatment of fatigue for over sixty years, Robert Hockey examines its many aspects - social history, neuroscience, energetics, exercise physiology, sleep and clinical implications - and develops a new motivational control theory, in which fatigue is treated as an emotion having a fundamental adaptive role in the management of goals. He then uses this new perspective to explore the role of fatigue in relation to individual motivation, working life and well-being.

When human muscle fatigues, athletic performance becomes impaired. For those individuals suffering muscle or metabolic diseases the effects of muscle fatigue can make everyday tasks difficult. Understanding the scientific processes responsible for skeletal muscle fatigue is therefore central to the study of the physiology of sport, exercise and health. Written by a team of leading international exercise scientists, this book explores the mechanisms of muscle fatigue and presents a comprehensive survey of current research on this important topic. Examining the wide variety of protocols, assessment methods and exercise models used to study muscle fatigue, the book explores the differential effects of fatigue as influenced by: age gender fitness and training the use of ergogenic aids medical conditions including cerebral palsy, muscular dystrophy and glycogenosis. Human Muscle Fatigue covers both clinical and applied approaches in sport and exercise physiology and devotes an entire section to the conceptual framework underpinning research in this area, helping readers from a wide range of backgrounds to engage with the topic. Accessible and detailed, this book is a key text for students and practitioners working in exercise and sports science, medicine, physical therapy and health.

Muscle and Exercise Physiology is a comprehensive reference covering muscle and exercise physiology, from basic science to advanced knowledge, including muscle power generating capabilities, muscle energetics, fatigue, aging and the cardio-respiratory system in exercise performance. Topics presented include the clinical importance of body responses to physical exercise, including its impact on oxygen species production, body immune system, lipid and carbohydrate metabolism, cardiac energetics and its functional reserves, and the health-related effects of physical activity and inactivity. Novel topics like critical power, ROS and muscle, and heart muscle physiology are explored. This book is ideal for researchers and scientists interested in muscle and exercise physiology, as well as students in the biological sciences, including medicine, human movements and sport sciences. - Contains basic and state-of-the-art knowledge on the most important issues of muscle and exercise physiology, including muscle and body adaptation to physical training, the impact of aging and physical activity/inactivity - Provides both the basic and advanced knowledge required to understand mechanisms that limit physical capacity in both untrained people and top class athletes - Covers advanced content on muscle power generating capabilities, muscle energetics, fatigue and aging

To provide a forum for discussion, the International Conference on Fatigue Science was organized, the first being held in 2002 in Sandhamn, Sweden, and the second in 2005 in Karuizawa, Japan. Subsequently it was decided that the papers presented at the two conferences should be collected. The result is an authoritative guide to recent progress in the molecular and neural mechanisms of fatigue and in the development of the ways to prevent and overcome fatigue and chronic fatigue.

This volume presents the proceedings of a muscle symposium, which was held as the Fourth Fujihara seminar on October 28 - November 1, 2002, at Hakone, Japan. This volume covers all fields of muscle biology, from molecules to humans. This book provides information about recent progress of muscle research as well as the problems that remain to be investigated. This volume will stimulate muscle investigators to design and perform novel experiments to clarify the mysteries in muscle contraction.

Fatigue is an important concern for all athletes, sportspeople and coaches, and in clinical exercise science. There remains considerable debate about the definition of fatigue, what causes it, what its impact is during different forms of exercise, and what the best methods are to combat fatigue and improve performance. This is the first student-focused book to survey the contemporary research evidence into exercise-induced fatigue and to discuss how knowledge of fatigue can be applied in sport and exercise contexts. The book examines the different ‘types’ of fatigue and the difficulties of identifying which types are prevalent during different types of exercise, including a discussion of the most important methods for measuring fatigue. It introduces the fundamental science of fatigue, focussing predominantly on covering physiological aspects, and explores key topics in detail, such as energy depletion, lactic acid, dehydration, electrolytes and minerals, and the perception of fatigue. Every chapter includes real case studies from sport and exercise, as well as useful features to aid learning and understanding, such as definitions of key terms, guides to further reading, discussion questions, and principles for training and applied practice. Fatigue in Sport and Exercise is an invaluable companion for any degree-level course in sport and exercise physiology, fitness and training, or strength and conditioning.

The Physiology of Physical Training provides complete coverage of the physiological and methodological aspects of physical training, providing essential knowledge for anyone involved in exercise physiology. Physiological processes at the cellular level (and for the whole organism) are covered to better explain particular training methods and convey a deeper knowledge and understanding of training techniques. Coverage of exercise training-induced adaptive responses and the most appropriate training methods to bring about targeted adaptive changes are also included. This is the perfect reference for researchers of physiology/kinesiology and human kinetics, practicing coaches, graduate students and sports medicine specialists. - Describes exercise-induced adaptation, from the cell to the whole body - Demonstrates practical applications of exercise for injury, disease prevention and improved physical performance - Fully integrates the knowledge of molecular exercise physiology and training methods

There are approximately 4,000 fatalities in crashes involving trucks and buses in the United States each year. Though estimates are wide-ranging, possibly 10 to 20 percent of these crashes might have involved fatigued drivers. The stresses associated with their particular jobs (irregular schedules, etc.) and the lifestyle that many truck and bus drivers lead, puts them at substantial risk for insufficient sleep and for developing short- and long-term health problems. Commercial Motor Vehicle Driver Fatigue, Long-Term Health and Highway Safety assesses the state of knowledge about the relationship of such factors as hours of driving, hours on duty, and periods of rest to the fatigue experienced by truck and bus drivers while driving and the implications for the safe operation of their vehicles. This report evaluates the relationship of these factors to drivers' health over the longer term, and identifies improvements in data and research methods that can lead to better understanding in both areas.