This text and the terminology developed by the Papanicolaou Society of Cytopathology (P.S.C.) represents an important advance in the field of pancreaticobiliary cytopathology. This textbook/atlas is designed to present a comprehensive and state of the art approach to the cytologic diagnosis and reporting of pancreaticobiliary lesions. Chapters address each of the diagnostic categories defined by the P.S.C. The definition of each category along with the clinical pathologic entities contained within the category are discussed along with specific cytologic criteria for inclusion of a cytologic specimen within the category. Each chapter is lavishly illustrated demonstrating diagnostic criteria and examples of lesions contained within the category. Additionally, appropriate ancillary testing is discussed and where appropriate illustrated. Each chapter concludes with a discussion of appropriate management as well as estimates of malignancy risk for the category. The Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology: Definitions, Criteria, Ancillary Testing and Management will provide the reader with a unified approach to diagnosing and reporting interpretations of cytologic specimens obtained from the pancreaticobiliary tract. This text/atlas will serve as a reference guide for pathologists, surgeons, endoscopists and radiologists.

This text presents comprehensive review of the recommendations of the Papanicolaou Society of Cytopathology for reporting results of respiratory cytology specimens along with advances in diagnostic, prognostic, and predictive immunohistochemical and molecular techniques which can be performed on cytology specimens.The majority of the text focuses on the standardized terminology and nomenclature for respiratory cytology as recommended by the Papanicolaou Society of Cytopathology. Each of the diagnostic categories are described in depth and formal definitions for each category are given along with cytologic criteria. Explanatory notes are given discussing limitations of the category as well as its malignancy risk and reproducibility. Management recommendations are supplied for each category. Sample reports documenting the preferred reporting format are also given. Each category is associated with a reference list establishing the evidence based nature of the categories. An in depth discussion of ancillary testing is provided, including the utilization of microbiologic culture, immunohistochemistry, and molecular techniques. Substantial emphasis is placed on molecular diagnostics necessary for optimization of personalized testing and the appropriate use of targeted therapies. The text represents a comprehensive resource for the state of the science of the cytologic diagnosis of respiratory lesions.

This book describes a novel and proven approach to cytologically classify urinary samples for the detection of bladder cancer and lesions of the upper urinary tract. The new method is based on the collective experience of knowledgeable cytopathologists who have tested the terminology within their own laboratories for reproducibility and predictability of neoplasms of the urinary tract. Accompanying the written criteria for each diagnostic category are meticulously photographed exemplars of the cellular features, with cogently annotated descriptions of the photographs. The book thereby performs as an atlas for microscopists involved in diagnostic cytopathology at all levels of their education. Included in the targeted readership are experienced pathologists, cytotechnologists, and students of both professional groups. The new terminology also considers the clinical aspects of patient management. Written by experts in the field who convened at the 18th International Congress of Cytology in Paris, The Paris System for Reporting Urinary Cytology presents a global standard for reporting and a new philosophic approach that maximizes the strengths of detecting the potentially lethal high grade lesions by urinary cytology, and recognizes without apology the inability to reliably detect the low grade lesions in urinary cytology. The Concept has been endorsed by the American Society Of Cytopathology, and the International Academy of Cytology.

The Second Edition of The Milan System for Reporting Salivary Gland Cytopathology, like the First Edition, represents a collaborative effort by a multidisciplinary group of cytopathologists, surgical pathologists, molecular pathologists, radiologists, and head and neck surgeons. This international group shares the goal of creating a practical and uniform reporting system for salivary gland fine needle aspiration (FNA). This book is organized into six general diagnostic categories: “Non-Diagnostic,” “Non-Neoplastic,” “Atypia of Undetermined Significance (AUS),” “Neoplasm: Benign,” “Neoplasm: Salivary Gland Neoplasm of Uncertain Malignant Potential (SUMP),” “Suspicious for Malignancy,” and “Malignant.” It includes definitions, morphologic criteria, and explanations for each of the diagnostic categories. Specific chapters are dedicated to the application of the latest available ancillary studies, radiologic features of salivary gland lesions, clinical management, and histological considerations including updates from the most recent 5th Edition WHO blue book. The Milan System for Reporting Salivary Gland Cytopathology 2nd Edition represents an essential step towards increasing the overall effectiveness of salivary gland FNA and fostering better communication between clinicians and between institutions to improve overall patient care.

This updated edition remains the essential text for pathologists seeking to make accurate diagnoses from the vast number of differentials.

This book offers clear, up-to-date guidance on how to report cytologic findings in cervical, vaginal and anal samples in accordance with the 2014 Bethesda System Update. The new edition has been expanded and revised to take into account the advances and experience of the past decade. A new chapter has been added, the terminology and text have been updated, and various terminological and morphologic questions have been clarified. In addition, new images are included that reflect the experience gained with liquid-based cytology since the publication of the last edition in 2004. Among more than 300 images, some represent classic examples of an entity while others illustrate interpretative dilemmas, borderline cytomorphologic features or mimics of epithelial abnormalities. The Bethesda System for Reporting Cervical Cytology, with its user-friendly format, is a “must have” for pathologists, cytopathologists, pathology residents, cytotechnologists, and clinicians.

This book is the culmination of an international effort to bring consistency and diagnostic efficiency to effusion cytology for the sake of patient care. The authors recognize special challenges in serous fluid cytopathology, such as reporting the presence of Mullerian epithelium in peritoneal fluids. What is an appropriate serous fluid volume to ensure adequacy? How should mesothelial proliferations be reported and is it appropriate to make an interpretation of malignant mesothelioma? How specific should a report be regarding the origin and subtyping of tumors found in serous fluids? What are the appropriate quality monitors for this specimen type? Special chapters on considerations for peritoneal washings, cytopreparatory techniques, mesothelioma and quality management are included to address these issues. The text contains literature reviews that elucidate existing evidence in support of current practices and recommendations. Expert opinions on where evidence was lacking, the most common practices were adopted by consensus, and where there was no commonality, are employed. Written by experts in the field, The International System for Serous Fluid Cytopathology serves as a collaborative effort between the International Academy of Cytology and the American Society for Cytopathology and calls upon participation of the international cytopathology and oncology communities to contribute to the development of a truly international system for reporting serous fluid cytology

This book introduces basic ROSE techniques and resources required to set up ROSE service. It reviews the cytomorphologic features that are recognizable during ROSE, including those important for sample adequacy, specimen triage, preliminary interpretation, and potential diagnostic pitfalls. Economic and regulatory aspects are discussed as well as the pros and cons of telecytology. The book is formatted for clinical settings, simulating the ROSE process that occurs in the ultrasound room, CT room, bronchoscopy suite, and endoscopy suite. Each chapter focuses on the cytomorphologic clues and pitfalls of the entities specific to that clinical setting. Rapid On-Site Evaluation: A Practical Guide will be a valuable resource for pathologists, cytotechnologists, physicians who perform biopsies and/or ROSE evaluation, and trainees for utilizing ROSE and improving diagnostic performance of biopsies.

This book focuses on all aspects of pancreatic pathology, from key features of benign and malignant lesions to diagnostic pearls for differential diagnosis of encountered entities in pancreatobiliary fine needle aspirations and small biopsies. Chapters include a brief introduction and a practical approach to diagnose benign and malignant lesions. The key cytomorphologic features and main differential diagnoses are also summarized in concise tables. Richly colored images complement the text and represent key findings pertaining to the text discussion. An important and current chapter on molecular testing proves to be very useful for the readership for their daily practice in this era of targeted therapy. Written by experts in the fields, all authors contribute their collective experience of preeminent cytopathology service spanning a long time span. Pancreas and Biliary Tract Cytohistology serves as a practical resource for cytotechnologists, cytopathologists and pathologists who are practicing cytopathology and rendering diagnoses on small biopsy samples on pancreatic lesions.

Features new to this edition include chapters on structure and ultrastructure of cells, current status of molecular biology and its application to diagnostic cytology, cell response to injury, cytology of cancer, AIDS, and flow cytometry; major revisions of chapters on carcinoma of the uterine cervix, carcinoma of the endometrium, urinary tract, aspiration biopsy, and automated cytology; and a new section on in-situ hybridization.