A journey into the sub-microscopic world of molecular machines. Readers are first introduced to the types of molecules built by cells: proteins, nucleic acids, lipids, and polysaccharides. Then, in a series of distinctive illustrations, the reader is guided through the interior world of cells, exploring the ways in which molecules work in concert to perform the processes of living. Finally, the author shows us how vitamins, viruses, poisons, and drugs each have their effects on the molecules in our bodies. David Goodsell, author and illustrator, has prepared a fascinating introduction to biochemistry for the non-specialist. His book combines a lucid text with an abundance of drawings and computer graphics that present the world of cells and their components in a truly unique way.

Life, Hoffman argues, emerges from the random motions of atoms filtered through the sophisticated structures of our evolved machinery. People are essentially giant assemblies of interacting nanoscale machines.

Fix the machinery of your life . . . and serenity and wealth will follow. Starkly compelling in its simplicity, in The Systems Mindset: Managing the Machinery of Your Life, Sam Carpenter expands on the core inspirational element of his business bestseller, Work the System: The Simple Mechanics of Making More and Working Less, now in its third edition. Mindset is your path to quickly breaking free: to making a small tweak in how you see your world and then using that more accurate vision to get what you’ve always wanted from work, relationships, and health. When the systems mindset epiphany strikes, you will instantly see the visible and invisible machinery that determines your existence. With this startling new perception, you’ll see that your world is not a confusing array of sights, sounds, and events and, instead, grasp that it’s a simple and logical collection of systems, systems that can be quickly adjusted to deliver the life results you’ve always wanted. You will never be the same.

Thermodynamics was created in the ?rst half of the 19th century as a theory designed to explain the functioning of heat engines converting heat into mechanical work. In the course of time, while the scope of research in this ?eld was being extended to a wider and wider class of energy transformations, thermodynamics came to be considered as a general theory of machines identi?ed with energy transducers. Imp- tant progress in biochemistry in the ?rst half of the 20th century, and in molecular biology in the second half, made it possible to think of treating even living organisms as machines, at least on the subcellular level. However, success in applying thermodynamics to elucidate the phenomenon of life has been rather mitigated. Two reasons seem to be responsible for this unsatisfactory s- uation. Nineteenth century thermodynamics dealt only with simple (homogeneous) systems in complete equilibrium. Although during the 20th century a nonequilibrium thermodynamics was developed, sta- ing with the Onsager theory of linear response and ending with the Prigogine nonlinear theory of dissipative structures, these theories still concern the originally homogeneous systems. Because living organisms are complex systems with a historically frozen spatial and functional structure, a thermodynamics of both nonequilibrium and complex s- tems is needed for their description. The ?rst goal of the present book is to formulate the foundations of such a thermodynamics.

Discussions of the basic structural, nanotechnology, and system engineering principles, as well as an introductory overview of essential concepts and methods in biotechnology, will be included. Text is presented side-by-side with extensive use of high-quality illustrations prepared using cutting edge computer graphics techniques. Includes numerous examples, such applications in genetic engineering. Represents the only available introduction and overview of this interdisciplinary field, merging the physical and biological sciences. Concludes with the authors' expert assessment of the future promise of nanotechnology, from molecular "tinkertoys" to nanomedicine. David Goodsell is author of two trade books, Machinery of Life and Our Molecular Nature, and Arthur Olson is the world's leader in molecular graphics and nano-scale representation.

This book is designed specifically as a guide for Computer Scientists needing an introduction to Cell Biology. The text explores three different facets of biology: biological systems, experimental methods, and language and nomenclature. The author discusses what biologists are trying to determine from their experiments, how various experimental procedures are used and how they relate to accepted concepts in computer science, and the vocabulary necessary to read and understand current literature in biology. The book is an invaluable reference tool and an excellent starting point for a more comprehensive examination of cell biology.

Two centuries ago, American criminal justice was run primarily by laymen. Jury trials passed moral judgment on crimes, vindicated victims and innocent defendants, and denounced the guilty. But since then, lawyers have gradually taken over the process, silencing victims and defendants and, in many cases, substituting plea bargaining for the voice of the jury. The public sees little of how this assembly-line justice works, and victims and defendants have largely lost their day in court. As a result, victims rarely hear defendants express remorse and apologize, and defendants rarely receive forgiveness. This lawyerized machinery has purchased efficient, speedy processing of many cases at the price of sacrificing softer values, such as reforming defendants and healing wounded victims and relationships. In other words, the U.S. legal system has bought quantity at the price of quality, without recognizing either the trade-off or the great gulf separating lawyers' and laymen's incentives, values, and powers. In The Machinery of Criminal Justice, author Stephanos Bibas surveys the developments over the last two centuries, considers what we have lost in our quest for efficient punishment, and suggests ways to include victims, defendants, and the public once again. Ideas range from requiring convicts to work or serve in the military, to moving power from prosecutors to restorative sentencing juries. Bibas argues that doing so might cost more, but it would better serve criminal procedure's interests in denouncing crime, vindicating victims, reforming wrongdoers, and healing the relationships torn by crime.

Intelligent Fault Diagnosis and Remaining Useful Life Prediction of Rotating Machinery provides a comprehensive introduction of intelligent fault diagnosis and RUL prediction based on the current achievements of the author's research group. The main contents include multi-domain signal processing and feature extraction, intelligent diagnosis models, clustering algorithms, hybrid intelligent diagnosis strategies, and RUL prediction approaches, etc. This book presents fundamental theories and advanced methods of identifying the occurrence, locations, and degrees of faults, and also includes information on how to predict the RUL of rotating machinery. Besides experimental demonstrations, many application cases are presented and illustrated to test the methods mentioned in the book. This valuable reference provides an essential guide on machinery fault diagnosis that helps readers understand basic concepts and fundamental theories. Academic researchers with mechanical engineering or computer science backgrounds, and engineers or practitioners who are in charge of machine safety, operation, and maintenance will find this book very useful. - Provides a detailed background and roadmap of intelligent diagnosis and RUL prediction of rotating machinery, involving fault mechanisms, vibration characteristics, health indicators, and diagnosis and prognostics - Presents basic theories, advanced methods, and the latest contributions in the field of intelligent fault diagnosis and RUL prediction - Includes numerous application cases, and the methods, algorithms, and models introduced in the book are demonstrated by industrial experiences

Ecologische studie.