In the wake of a pandemic virus that rapidly spreads throughout the world killing millions of people, Dennis and Andi Jensen flee the ensuing panic and escape to the mountains while scientist Cara Porter makes a potentially fatal mistake in her laboratory.

This book provides in-depth information on all key aspects of geminivirus biology, e.g. the genetics and evolution, global diversity and spread of these plant pathogens, as well as the molecular mechanisms underlying their virulence. Geminiviridae is one of the largest viral families, comprising numerous plant-infecting viruses that cause diseases in crops and weeds. These diseases have been reported from nearly all continents, in particular Asia, Europe, Africa and America. The book summarizes the current state of knowledge on the interactions between plant host and virus. In addition, it discusses advances regarding the trans-replication of satellite molecules and its effect on geminiviral pathogenesis, as well as pest management strategies to combat these diseases in the field. Given its scope, the book is a must-read reference guide for all researchers and advanced students working in virology, agriculture and plant biotechnology..

Concern about the environmental consequences of the widespread use of pesticides has increased, and evidence of pesticide-resistant virus vectors have continued to emerge. This volume presents a timely survey of the mechanisms of plant resistance and examines current developments in breeding for resistance, with particular emphasis on advances in genetic engineering which allow for the incorporation of viral genetic material into plants. Discusses the mechanisms of innate resistance in strains of tobacco, tomato, and cowpea; various aspects of induced resistance, including the characterization and roles of the pathogenesis-related proteins; antiviral substances and their comparison with interferon; and cross-protection between plant virus strains. Also presents several papers which evaluate the status of genetic engineering as it relates to breeding resistant plants. Among these are discussions of the potential use of plant viruses as gene vectors, gene coding for viral coat protein, satellite RNA, and antisense RNA, and practical issues such as the durability of resistant crop plants in the field.

Advances in Virus Research, Volume 108, in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on topics including Virus infections of the developing brain, Geminivirus assembly, Flavivirus assembly, Cell-cell transmission, Archael virus assembly, Potyvirus assembly, Poxvirus assembly and exit, Mycovirus assembly, Reo/orbivirus assembly and exit, Giant virus assembly, Quasi-enveloped virus assembly/exit, and Betaherpesvirus assembly and exit. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Advances in Virus Research series - Includes the latest information on virus assembly and exit pathways

Ideally suited to horticulturalists and plant virologists, this highly useful text offers a multidisciplinary view on one of the major diseases of tomato crops, the tomato yellow leaf curl disease. It deals with epidemiological aspects of the disease as well as integrated pest management in the field. Coverage discusses the efforts aimed at breeding tomato plants resistant to the virus by classical breeding, by marker-assisted breeding and by genetic engineering.

The seminal text Plant Virology is now in its fifth edition. It has been 10 years since the publication of the fourth edition, during which there has been an explosion of conceptual and factual advances. The fifth edition of Plant Virology updates and revises many details of the previous edition while retaining the important earlier results that constitute the field's conceptual foundation. Revamped art, along with fully updated references and increased focus on molecular biology, transgenic resistance, aphid transmission, and new, cutting-edge topics, bring the volume up to date and maintain its value as an essential reference for researchers and students in the field. - Thumbnail sketches of each genera and family groups - Genome maps of all genera for which they are known - Genetic engineered resistance strategies for virus disease control - Latest understanding of virus interactions with plants, including gene silencing - Interactions between viruses and insect, fungal, and nematode vectors - Contains over 300 full-color illustrations

This book provides a comprehensive look at the field of plant virus evolution. It is the first book ever published on the topic. Individual chapters, written by experts in the field, cover plant virus ecology, emerging viruses, plant viruses that integrate into the host genome, population biology, evolutionary mechanisms and appropriate methods for analysis. It covers RNA viruses, DNA viruses, pararetroviruses and viroids, and presents a number of thought-provoking ideas.

The book represents basic information about viral-caused and viral-like diseases in many weeds. Many scientific reports have demonstrated that weeds serve as a reservoir or alternative hosts for geminivirus genera (e.g., Begomovirus) for survival and spread in the absence of main crops. This book represents a tip of the iceberg of the diversity of begomoviruses in weeds. The recognition that geminivirus strains are capable of rapidly diverging through multiple mechanisms, underscores the need for accurate molecularly based methods that permit detection and tracking of biologically significant variants. Molecular approaches must combine knowledge of biology, ecology and the ability to monitor both conserved sequences and specific sites, most likely to undergo alteration with phylogenetic predictions to facilitate accurate identification and tracking of begomovirus variants and to also recognize new or resurgent viruses. Establishing databases of baseline sequences for extant viruses will permit future comparisons in establishing and interpreting disease patterns and associated trends for vector populations. With the development of reliable computational recombination detection tools and an increasing number of available genome sequences, many studies have reported evidence of recombination in a wide range of virus genera. The book also focuses on the first geminivirus database (GVDB) that contains biotic, molecular and in silico information which will permit rapid and accurate begomovirus identification and the selection of relevant viral species for the development of disease resistance/management strategy to the geminiviruses specific to individual crop production areas. To close, there is one chapter on the international and national status of geminivirus infection in various host weeds. Furthermore, the book's heart discusses the most recent cutting-edge of research that makes this book essential reading for everyone, from researchers to scholars to students, working with molecular and computational aspects of geminivirus research as well as scientists already familiar with the area.

Environmental Virology, Volume 101, the latest in the Advances in Virus Research series, contains new, informative updates on the topic. First published in 1953, this series covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology. Updates to this release include sections on the host landscape and vector behavior, key determinants of plant virus evolution and emergence, plant virome analysis using spatial metagenomics, host range evolution in generalist viruses, the influence of environment, water-mediated spread and transmission of viruses, viruses transmitted by means other than insect vectors, and more. - Contains contributions from leading authorities in the field of virology - Informs and updates on all the latest developments in the field - Features a diverse range of virology topics, including discussions of host landscape and vector behavior and viruses transmitted by means other than insect vectors

Eleven years ago the circular DNA of a novel single-stranded virus has been cloned and partially characterized by Nishizawa and Okamoto and their colleagues. According to the initials of the patient from whom the isolate originated, the virus was named TT virus. This name has been subsequently changed by the International Committee on Taxonomy of Viruses (ICTV) into Torque teno virus, permitting the further use of the abbreviation TTV. Although initially suspected to play a role in non A –E hepatitis, subsequent studies failed to support this notion. Within a remarkably short period of time it became clear that TT viruses are widely spread globally, infect a large proportion of all human populations studied thus far and represent an extremely heterogeneous group of viruses, now labelled as Anelloviruses. TT virus-like infections have also been noted in various animal species. The classification of this virus group turns out to be difficult, their DNA contains between 2200 and 3800 nucleotides, related so-called TT-mini-viruses and a substantial proportion of intragenomic recombinants further complicate attempts to combine these viruses into a unifying phylogenetic concept.