It fits in every jacket pocket and provides a quick reference guide for all clinically active physicians in hospitals or doctor’s practices. With the nearly unmanageable number of antibiotics an up-to-date, clear-cut presentation is essential. In clear tables – sorted by substances, pathogens and indications – spectra and recommendations for dosages can be easily looked up. Special problems such as the use of antibiotics during pregnancy, in perioperative antibiotic prophylaxis, and for renal and hepatic insufficiency are also included. A guide for your daily work: handy, concise, and clear. Adjusted to European standards: Up-to-date substances, authorizations, resistances and trade names. The first guide to antibiotic therapy for Europe!

Handy – concise – clear The “always on-hand” pocket guide to the treatment of infectious diseases. - The most important antibiotics and antimycotics: Spectrum – dosage – side-effects - Numerous tables sorted by substances, pathogens, indications - Administration of antibiotics during pregnancy, renal and hepatic insufficiency, dialysis - Including statements on the cost of therapy Numerous tips and troubleshooting guides on topics such as: - Potential mistakes - Therapy failures - Perioperative antibiotic prophylaxis Adjusted to European standards: Up-to-date substances, authorizations, resistances and trade names. The first guide to antibiotic therapy for Europe! All in all, an approach that looks towards the future in which antimicrobial resistance will certainly represent an ever-growing obstacle for the medical class, and for which books like this will undoubtedly represent a precious resource. Giuseppe Cornaglia, MD, PhD President, European Society of Clinical Microbiology and Infectious Diseases (ESCMID) This book will most certainly be a valuable asset for all those treating patients with infections. While primarily aimed at the hospital setting, most of the very useful information can certainly be used in other healthcare settings, too. Andreas Voss Professor of Clinical Microbiology and Infection Control Radboud University Nijmegen Medical Centre and Canisius-Wilhelmina Hospital Nijmegen, The Netherlands

Antibiotics and Antimicrobial Resistance Genes (AMR) in the Environment summarizes and updates information on antibiotic producing organisms and their resistance and entry routes in soil, air, water and sediment. As antibiotic use continues to rise in healthcare, their fate, bioavailability and biomonitoring, and impacts on environment and public health are becoming increasingly important. The book addresses the impact of antibiotics and AMR to environment and public health and risk assessment. Moreover, it focused on the metagenomics and molecular techniques for the detection of antibiotics and antimicrobial genes. Lastly, it introduces management strategies, such as treatment technologies for managing antibiotics and AMR/ARGs-impacted environment, and bioremediation approaches. - Summarizes and updates information on antibiotics and AMR/ARGs production and its fate and transport in the environment - Includes phytoremediation and bioremediation technologies for environmental management - Provides analysis of risk assessment of antibiotic resistance genes to help understand the environmental and socioeconomic impacts of antibiotics and AMR/ARGs

Antimicrobial resistance (AMR) is one of the deadliest threats to global public health. This book focuses on dynamics in the landscape of AMR while informing about the latest technologies and strategies to mitigate it. The menace of AMR in different niches, routes of penetration across various domains, socio-economic impact, and the need for a 'One Health' approach in mitigating AMR has been emphasized. Factors involved in AMR, underlying mechanisms, and pharmacometrics in developing antimicrobials are highlighted. Emphasis is given to emerging technologies that are sustainable, scalable, and applicable to the global community, such as big data analytics, bioactive agents, phage therapy, and nanotechnology. The book also explores current and alternative treatment strategies to combat AMR, emphasizing the use of nanoparticles to target pathogens and as a viable alternative to antibiotics.

Drs. Cohen, Powderly and Opal, three of the most-respected names in infectious disease medicine, lead a diverse team of international contributors to bring you the latest knowledge and best practices. Extensively updated, the fourth edition includes brand-new information on advances in diagnosis of infection; Hepatitis C; managing resistant bacterial infections; and many other timely topics. An abundance of photographs and illustrations; a practical, clinically-focused style; highly-templated organization; and robust interactive content combine to make this clinician-friendly resource the fastest and best place to find all of the authoritative, current information you need. - Hundreds of full-color photographs and figures provide unparalleled visual guidance. - Consistent chapter organization and colorful layouts make for quick searches. - Clinically-focused guidance from "Practice Points" demonstrates how to diagnose and treat complicated problems encountered in practice. - The "Syndromes by Body System", "HIV and AIDS", and "International Medicine" sections are designed to reflect how practicing specialists think when faced with a patient. - Sweeping updates include new or revised chapters on: - Hepatitis C and antivirals - Fungal infection and newer antifungals - Microbiome and infectious diseases as well as advances in diagnosis of infection; Clostridium difficile epidemiology; infection control in the ICU setting; Chlamydia trachomatis infection; acquired syndromes associated with autoantibodies to cytokines;; management of multidrug resistant pathogens; probiotics, polymyxins, and the pathway to developing new antibiotics - HIV including HIV and aging, antiretroviral therapy in developing countries, and cure for HIV. - Online Antimicrobial pharmacokinetics mannequin, as well an all new HIV medicine mannequin are a useful visual source of treatment information

This is the second edition of the WHO handbook on the safe, sustainable and affordable management of health-care waste--commonly known as "the Blue Book". The original Blue Book was a comprehensive publication used widely in health-care centers and government agencies to assist in the adoption of national guidance. It also provided support to committed medical directors and managers to make improvements and presented practical information on waste-management techniques for medical staff and waste workers. It has been more than ten years since the first edition of the Blue Book. During the intervening period, the requirements on generators of health-care wastes have evolved and new methods have become available. Consequently, WHO recognized that it was an appropriate time to update the original text. The purpose of the second edition is to expand and update the practical information in the original Blue Book. The new Blue Book is designed to continue to be a source of impartial health-care information and guidance on safe waste-management practices. The editors' intention has been to keep the best of the original publication and supplement it with the latest relevant information. The audience for the Blue Book has expanded. Initially, the publication was intended for those directly involved in the creation and handling of health-care wastes: medical staff, health-care facility directors, ancillary health workers, infection-control officers and waste workers. This is no longer the situation. A wider range of people and organizations now have an active interest in the safe management of health-care wastes: regulators, policy-makers, development organizations, voluntary groups, environmental bodies, environmental health practitioners, advisers, researchers and students. They should also find the new Blue Book of benefit to their activities. Chapters 2 and 3 explain the various types of waste produced from health-care facilities, their typical characteristics and the hazards these wastes pose to patients, staff and the general environment. Chapters 4 and 5 introduce the guiding regulatory principles for developing local or national approaches to tackling health-care waste management and transposing these into practical plans for regions and individual health-care facilities. Specific methods and technologies are described for waste minimization, segregation and treatment of health-care wastes in Chapters 6, 7 and 8. These chapters introduce the basic features of each technology and the operational and environmental characteristics required to be achieved, followed by information on the potential advantages and disadvantages of each system. To reflect concerns about the difficulties of handling health-care wastewaters, Chapter 9 is an expanded chapter with new guidance on the various sources of wastewater and wastewater treatment options for places not connected to central sewerage systems. Further chapters address issues on economics (Chapter 10), occupational safety (Chapter 11), hygiene and infection control (Chapter 12), and staff training and public awareness (Chapter 13). A wider range of information has been incorporated into this edition of the Blue Book, with the addition of two new chapters on health-care waste management in emergencies (Chapter 14) and an overview of the emerging issues of pandemics, drug-resistant pathogens, climate change and technology advances in medical techniques that will have to be accommodated by health-care waste systems in the future (Chapter 15).

Surgical site infections are caused by bacteria that get in through incisions made during surgery. They threaten the lives of millions of patients each year and contribute to the spread of antibiotic resistance. In low- and middle-income countries, 11% of patients who undergo surgery are infected in the process. In Africa, up to 20% of women who have a caesarean section contract a wound infection, compromising their own health and their ability to care for their babies. But surgical site infections are not just a problem for poor countries. In the United States, they contribute to patients spending more than 400 000 extra days in hospital at a cost of an additional US $10 billion per year. No international evidence-based guidelines had previously been available before WHO launched its global guidelines on the prevention of surgical site infection on 3 November 2016, and there are inconsistencies in the interpretation of evidence and recommendations in existing national guidelines. These new WHO guidelines are valid for any country and suitable to local adaptations, and take account of the strength of available scientific evidence, the cost and resource implications, and patient values and preferences.

Infections, especially those occurring postoperatively, remain a major problem in hospitals. This handy pocket-sized manual provides guidelines and protocols for preventing infections, and managing them if they occur. It covers various types of infection, and is suitable for members of infection control teams.