For Rayshell and her best friend Trish, senior year of high school is going to hell in a handbasket. The feud between Celestine and Daeva is bleeding into their world. When a mysterious visitor infiltrates her dreams, Rayshell is thrust into a realm of profound, otherworldly secrets. Together, Rayshell and Trish uncover the unbelievable—they are the living vessels for two banished Celestine guardians. Amidst mystical recollections and a wondrous magic system that shatters the veneer of their everyday lives, the two friends embark on a journey against time to connect with the Celestine guardians' allies in hopes of freeing them from their imprisonment. Simultaneously, the shadows cast by Daeva darken. The notorious outlaw, Merisek, has positioned himself to claim dominion over the Order of Existence—a trio of powerful artifacts capable of reshaping reality. Armed with two of these relics, Merisek races against the emergence of the Celestine guardians to claim the third. The stage is set for a showdown that will determine the fate of existence itself. Rayshell and Trish are all that stand between Merisek and his unhinged desire to twist the fabric of reality into his making. As the threads of destiny unravel, the question looms: who will be the author of existence, and what profound truths will be unveiled in the final, decisive act?

Spelled out of their world and into another, Celestine Guardians Navaryn and Lowenna remain trapped inside the bodies of highschool students. With the assistance of distant allies they fight to reclaim their stolen memories so that they can return home. But time is running out. The forces responsible for their banishment are close to possessing the Order of Existence which will give them the power to destroy all life. Will they return in time to save their world?

No. 2, pt. 2 of November issue each year from v. 19 (1963)-47 (1970) and v. 55 (1972)- contain the Abstracts of papers presented at the Annual Meeting of the American Society for Cell Biology, 3d (1963)-10th (1970) and 12th (1972)-

This book deals with the molecular mechanisms of membrane trafficking, a central eukaryotic cell biological process. In the post-genomic era many essential molecules involved in intracellular membrane/protein transport are emerging. A huge task now is to compile the molecular networks that govern these processes. Understanding of regulatory processes and participating molecules are likely to reveal global cellular regulatory circuits that couple membrane trafficking with other cellular functions. Such cell biological features are only starting to emerge. This book puts special emphasis on such mechanisms and processes. The contents discusses the role of coat proteins, tethering complexes, small rab GTPases, Sec1-family proteins and SNARE molecule phosphorylation in exocytosis, endocytosis and membrane fusion. In addition, the role of lipids in vesicle formation and membrane fusion, and some specialized cell biological denovo membrane generation processes are discussed.

Transposable elements are short lengths of DNA with the capacity to move between different points within a genome. This process can affect the function of genes at or near the insertion site. The present book gives an overview of the impact of transposable elements on plant genomes and explains how to recognize and study transposable elements, e.g. by using state-of-the-art strategies like “new generation sequencing.” Moreover, the impact of transposable elements on plant genome structure and function is reviewed in detail, and also illustrated in examples and case studies. The book is intended both for readers familiar with the field and for newcomers. With large-scale sequencing becoming increasingly available, more and more people will come across transposable element sequences in their data, and this volume will hopefully help to convince them that they are not just “junk DNA.”

This book provides an authoritative overview of botulinum neurotoxin (BoNT) treatment menus for 16 pain categories with an evidence-based literature review on each pain disorder, illustrative figures showing anatomy and techniques Introductory chapters cover basic information about the mechanism, function and the analgesic effects of the BoNTs based on the data derived from animal studies. Clinical chapters define pain in conditions such as post-herpetic and post-traumatic neuralgias, plantar fasciitis, low back pain, post-surgical pain syndromes and migraine in detail, provide discussion of current modes of treatment and updated information on BoNT therapy. Each chapter also includes illustrative case histories. The new edition is updated with all the new findings since the explosion in research and literature since 2015. New chapters on the history and pain in dentistry round out the update. Botulinum Toxin Treatment of Pain Disorders provides an invaluable resource for clinicians and researchers involved in the treatment of pain disorders including neurologists, pain medicine specialists, anesthesiologists, internists, those conducting research in pharmacology and toxicology as well as students in these areas.

Join a feisty crew as they complete their early missions to arrive at Long Island and defeat those at the collider who intend to send out a pulse that could set off dangerous plasma weapons.This pulse was powered by a small object the size of a baseball, the Black Stone.The many references to Atlantis are to show how this 'type' of electric current was what they used so long ago, from what they called, 'the firestone'.It's a fun ride with an Afterword designed to encourage research of your own.