An essential guide to the data, basic science, outcome studies and decision-making processes in blood and marrow stem cell transplantation.

An essential guide to the data, outcome studies and complex decision-making processes involved in blood and marrow stem cell transplantation.

The BMT Data Book provides a unique reference tool for all clinicians involved in bone marrow or blood cell transplantation.

An essential guide to the data, outcome studies and complex decision-making processes involved in blood and marrow stem cell transplantation.

In the late 1980s, a promising new treatment for breast cancer emerged: high-dose chemotherapy with autologous bone marrow transplantation or HDC/ABMT. By the 1990s, it had burst upon the oncology scene and disseminated rapidly before having been carefully evaluated. By the time published studies showed that the procedure was ineffective, more than 30,000 women had received the treatment, shortening their lives and adding to their suffering. This book tells of the rise and demise of HDC/ABMT for metastatic and early stage breast cancer, and fully explores the story's implications, which go well beyond the immediate procedure, and beyond breast cancer, to how we in the United States evaluate other medical procedures, especially life-saving ones. It details how the factors that drove clinical use--patient demand, physician enthusiasm, media reporting, litigation, economic exploitation, and legislative and administrative mandates--converged to propel the procedure forward despite a lack of proven clinical effectiveness. It also analyzes the limited effect of technology assessments before randomized clinical trials evaluated decisively the procedure and the ramifications of this system on healthcare today. Sections of the book consider the initial conditions surrounding the emergence of the new breast cancer treatment, the drivers of clinical use, and the struggle for evidence-based medicine. A concluding section considers the significance of the story for our healthcare system.

This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.

"Hematopoietic stem cell transplantation (HSCT) has evolved from primary use in hematologic malignancies and nonmalignant disease and solid tumors into a treatment option for many other diseases, and indications for HSCT continue to expand. The new edition of this manual provides comprehensive information on the ever-evolving specialty of HSCT, providing nurses and other practitioners with in-depth information on the entire HSCT process, from stem cell mobilization, collection, and infusion to potential complications and long-term effects. It also includes chapters on current research, emerging therapies, ethics, HSCT program development, and professional practice issues"--

Providing the practicing and trainee hematologist with a practical and immediately applicable compendium of answers the Clinical Manual of Blood and Bone Marrow Transplantation covers the spectrum of the hematopoietic cell transplant specialty, in particular practical issues in transplant patient care, and the set up and functioning of a transplant program. Supplies the practicing and trainee hematologist with a practical and immediately applicable compendium of answers to clinical questions Covers the spectrum of the hematopoietic cell transplant specialty, in particular practical issues in transplant patient care, and the set up and functioning of a transplant program Contains concise chapters written with a focus on tables, algorithms and figures to aid rapid referral Benefits from expert contributions from an international authorship

Educators are increasingly responsible for using data to improve teaching and learning in their schools. This helpful guide provides leaders with simple steps for facilitating accurate analysis and interpretation of data, while avoiding common errors and pitfalls. How to Make Data Work provides clear strategies for getting data into workable shape and creating an environment that supports understanding, analysis, and successful use of data, no matter what data system or educational technology tools are in place in your district. This accessible resource makes data easy to understand and use so that educators can better evaluate and maximize their systems to help their staff, students, and school succeed. With this tried-and-true guidance, you’ll be prepared to advocate for tools that adhere to data reporting standards, avoid misinterpretation of data, and improve the data use climate in your school.