This book examines the poorly understood transformations in rural landscapes and societies that formed the backbone of ancient empires.

Side by side with the westward drift of white Americans in the 1830's was the forced migration of the Five Civilized Tribes from Mississippi, Alabama, Georgia, and Florida. Both groups were deployed against the tribes of the prairies, both breaking the soil of the undeveloped hinterland. Both were striving in the years before the Civil War to found schools, churches, and towns, as well as to preserve orderly development through government and laws. In this book Grant Foreman brings to light the singular effect the westward movement of Indians had in the cultivation and settlement of the Trans-Mississippi region. It shows the Indian genius at its best and conveys the importance of the Cherokees, Chickasaws, Choctaws, Creeks, and Seminoles to the nascent culture of the plains. Their achievements between 1830 and 1860 were of vast importance in the making of America.

As the emerging field of proteomics continues to expand at an extremely rapid rate, the relative quantification of proteins, targeted by their function, becomes its greatest challenge. Complex analytical strategies have been designed that allow comparative analysis of large proteomes, as well as in depth detection of the core proteome or the interaction network of a given protein of interest. In Functional Proteomics: Methods and Protocols, expert researchers describe the latest protocols being developed to address the problems encountered in high-throughput proteomics projects, with emphasis on the factors governing the technical choices for given applications. The case studies within the volume focus on the following three crucial aspects of the experimental design: 1) the strategy used for the selection, purification and preparation of the sample to be analyzed by mass spectrometry, 2) the type of mass spectrometer used and the type of data to be obtained from it, and 3) the method used for the interpretation of the mass spectrometry data and the search engine used for the identification of the proteins in the different types of sequence data banks available. As a part of the highly successful Methods in Molecular BiologyTM series, the chapters compile step-by-step, readily reproducible laboratory protocols, lists of the necessary materials and reagents, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Functional Proteomics: Methods and Protocols is an ideal resource for all scientists pursuing this developing field and its multitudinous data.

This book explores how globalization and transculturality are useful theoretical tools for studying pre-modern societies and their long-distance connections. Among the themes explored are how these concepts can enhance our understanding of trade networks, the spread of religions, the diffusion of global fashions, the migration of technologies, public and private initiatives, and wider cultural changes. In this book, archaeologists and ancient historians demonstrate how in diverse contexts – from the Bronze Age to colonial times – humanity displayed an urge and an incredible capacity to connect with distant lands and people. Adopting and modifying approaches originally developed for the study of contemporary societies, it is possible to enhance our understanding of the human past, not only in economic terms, but also the cultural significance of such interconnections. This book provides both the wider public and the specialist reader with a fresh point of view on global issues relating to the past; in turn, allowing us to look anew at developments in the contemporary world. Its large chronological and geographical scope should prove appealing to those who want more than mere Eurocentric history. Teachers and students of world history and archaeology will find this book a useful resource.

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