Tendon Regeneration: Understanding Tissue Physiology and Development to Engineer Functional Substitutes is the first book to highlight the multi-disciplinary nature of this specialized field and the importance of collaboration between medical and engineering laboratories in the development of tissue-oriented products for tissue engineering and regenerative medicine (TERM) strategies. Beginning with a foundation in developmental biology, the book explores physiology, pathology, and surgical reconstruction, providing guidance on biological approaches that enhances tendon regeneration practices. Contributions from scientists, clinicians, and engineers who are the leading figures in their respective fields present recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field. - Provides an overview of tendon biology, disease, and tissue engineering approaches - Presents modern, alternative approaches to developing functional tissue solutions discussed - Includes valuable information for those interested in tissue engineering, tissue regeneration, tissue physiology, and regenerative medicine - Explores physiology, pathology, and surgical reconstruction, building a natural progression that enhances tendon regeneration practices - Covers recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field

Tendon problems are a common cause of foot and ankle pathology. In the past decade there has been significant advances in the management of these problems. This has been achieved not only by an improvement of surgical techniques but also through a better understanding of tendon injury and healing. In this issue we will review the recent advances in the diagnosis and treatment of common tendon problems beginning with a review of tendon healing. This issue will provide the reader with an excellent review of all that is new on this topic.

A comprehensive and authoritative review of the most important scientific and clinically relevant topics today in ligaments, tendons, and capsular biology, including their biomechanics and surgical reconstruction. The authors review the basic science of tendons in the hand and shoulder ligaments, the current clinical status of the shoulder and cruciate ligaments, and the latest advances in research on the healing of ligament and tendon to bone, artificial ligaments, and gene therapy. They also cover the major type 1 collagen soft tissues that are of particular interest to upper extremity surgeons and sports medicine specialists.

This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules.

This book provides insights into sports medicine addressing trauma of the hand and wrist. This collection of injuries invites readers to trace aetiology, diagnosis, relevant pathology, management principles, and outcomes of numerous injuries in elite and non-elite athletes. The authors present management principles and outcomes. It is an ideal reference for postgraduate musculoskeletal doctors and therapists for Orthopaedic and Sports Medicine postgraduate degrees. Each approach to deal with an injury is underlined by case reports. Readers will also find valuable questions and answers fro self-assessment purpose. Sports Injuries of the Hand and Wrist is aimed at sports doctors, musculoskeletal doctors, senior orthopedic trainees with an interest in upper limb, orthopedic trainees preparing for the FRCSOrth exam and similar international exams, as well as upper hand and wrist surgeons in the earlier years of their practice.

This quick-reference guide is the first book written specifically for the many third- and fourth-year medical students rotating on an orthopedic surgery service. Organized anatomically, it focuses on the diagnosis and management of the most common pathologic entities. Each chapter covers history, physical examination, imaging, and common diagnoses. For each diagnosis, the book sets out the typical presentation, options for non-operative and operative management, and expected outcomes. Chapters include key illustrations, quick-reference charts, tables, diagrams, and bulleted lists. Each chapter is co-authored by a senior resident or fellow and an established academic physician and is concise enough to be read in two or three hours. Students can read the text from cover to cover to gain a general foundation of knowledge that can be built upon when they begin their rotation, then use specific chapters to review a sub-specialty before starting a new rotation or seeing a patient with a sub-specialty attending. Practical and user-friendly, Orthopedic Surgery Clerkship is the ideal, on-the-spot resource for medical students and practitioners seeking fast facts on diagnosis and management. Its bullet-pointed outline format makes it a perfect quick-reference, and its content breadth covers the most commonly encountered orthopedic problems in practice.

Get the best results from the latest procedures with Tendon Surgery of the Hand, the only reference that offers comprehensive coverage of this complex and challenging area. World-renowned experts guide you through all of the newest techniques and technologies, equipping you to restore optimal function in your patients. It's your one-stop source for mastering today's best approaches to treating tendon injuries and disorders of the hand. - Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. - Successfully implement hot new repair techniques involving new suture materials, tendon sheath and pulley treatments, vascularized tendon grafts, and recent postoperative rehabilitation methods. - Improve your primary flexor tendon repair and rehabilitation treatment planning based on surgical and post-surgical care principles that clearly describe successful global methods and protocols. - Benefit from the collective knowledge and experience of an international group of surgeons, investigators, and therapists who offer unique and insightful techniques and advice. - See how to perform key techniques with exclusive operative videos online. - Access the complete contents online at expertconsult.com.

In this book, leading international surgeons with expertise in the field provide cutting-edge information on the surgical techniques to treat sports and trauma injuries of the elbow. Indications for the different techniques are clearly explained, and practical aspects that allow safe and reproducible clinical outcomes are described. For the common procedures, a number of surgical technique options are presented, ensuring that the reader gains a broader perspective on this evolving surgical field. Throughout, valuable tips and tricks are highlighted that will assist both the experienced and the training surgeon in achieving maximum efficiency in their surgical practice. The book includes hundreds of illustrations, line diagrams, and clinical and cadaveric photographs to assist the reader in appreciating the principles of the clinical anatomy and the surgical techniques. Videos aid in understanding the finer points of the procedures. Surgical Techniques for Sports and Trauma Related Injuries of the Elbow is published in collaboration with ISAKOS. It will provide readers with a new comprehension of the topic and will be of value to students, physiotherapists, sports physicians, and orthopaedic surgeons.