Statistical design is one of the fundamentals of our subject, being at the core of the growth of statistics during the previous century. In this book the basic theoretical underpinnings are covered. It describes the principles that drive good designs and good statistics. Design played a key role in agricultural statistics and set down principles of good practice, principles that still apply today. Statistical design is all about understanding where the variance comes from, and making sure that is where the replication is. Indeed, it is probably correct to say that these principles are even more important today.

The Wiley Classics Library consists of selected books that have become recognized classics in their respective fields. With these new unabridged and inexpensive editions, Wiley hopes to extend the life of these important works by making them available to future generations of mathematicians and scientists. This title addresses those basic aspects of research design which are common to many related fields in the social sciences, health sciences, education, and market research. The work presents a unified approach to a common core of problems of statistical design that exists in all these fields, along with basic similarities in practical solutions. Describing many examples and analogies that are 'portable' from application field to application field, Statistical Design for Research deals with designs that are the primary basis of research studies, but are neglected in most statistical textbooks that tend to concentrate on statistical analysis. This text takes a broader, more general and philosophical view of the statistics for the more fundamental aspects of design than do the standard treatments of experimental design. Extensively illustrated and carefully organized into seven chapters and 44 sections, this book can be readily consulted by research workers or graduate students!

Statistical Design-Chemometrics is applicable to researchers and professionals who wish to perform experiments in chemometrics and carry out analysis of the data in the most efficient way possible. The language is clear, direct and oriented towards real applications. The book provides 106 exercises with answers to accompany the study of theoretical principles. Forty two cases studies with real data are presented showing designs and the complete statistical analyses for problems in the areas chromatography, electroanalytical and electrochemistry, calibration, polymers, gas adsorption, semiconductors, food technology, biotechnology, photochemistry, catalysis, detergents and ceramics. These studies serve as a guide that the reader can use to perform correct data analyses.-Provides 42 case studies containing step-by-step descriptions of calculational procedures that can be applied to most real optimization problems-Contains 106 theoretical exercises to test individual learning and to provide classroom exercises and material for written tests and exams-Written in a language that facilitates learning for physical and biological scientists and engineers-Takes a practical approach for those involved in industrial optimization problems

This open access textbook provides the background needed to correctly use, interpret and understand statistics and statistical data in diverse settings. Part I makes key concepts in statistics readily clear. Parts I and II give an overview of the most common tests (t-test, ANOVA, correlations) and work out their statistical principles. Part III provides insight into meta-statistics (statistics of statistics) and demonstrates why experiments often do not replicate. Finally, the textbook shows how complex statistics can be avoided by using clever experimental design. Both non-scientists and students in Biology, Biomedicine and Engineering will benefit from the book by learning the statistical basis of scientific claims and by discovering ways to evaluate the quality of scientific reports in academic journals and news outlets.

In today's high-technology world, with flourishing e-business and intense competition at a global level, the search for the competitive advantage has become a crucial task of corporate executives. Quality, formerly considered a secondary expense, is now universally recognized as a necessary tool. Although many statistical methods are available for

This richly illustrated book provides an overview of the design and analysis of experiments with a focus on non-clinical experiments in the life sciences, including animal research. It covers the most common aspects of experimental design such as handling multiple treatment factors and improving precision. In addition, it addresses experiments with large numbers of treatment factors and response surface methods for optimizing experimental conditions or biotechnological yields. The book emphasizes the estimation of effect sizes and the principled use of statistical arguments in the broader scientific context. It gradually transitions from classical analysis of variance to modern linear mixed models, and provides detailed information on power analysis and sample size determination, including ‘portable power’ formulas for making quick approximate calculations. In turn, detailed discussions of several real-life examples illustrate the complexities and aberrations that can arise in practice. Chiefly intended for students, teachers and researchers in the fields of experimental biology and biomedicine, the book is largely self-contained and starts with the necessary background on basic statistical concepts. The underlying ideas and necessary mathematics are gradually introduced in increasingly complex variants of a single example. Hasse diagrams serve as a powerful method for visualizing and comparing experimental designs and deriving appropriate models for their analysis. Manual calculations are provided for early examples, allowing the reader to follow the analyses in detail. More complex calculations rely on the statistical software R, but are easily transferable to other software. Though there are few prerequisites for effectively using the book, previous exposure to basic statistical ideas and the software R would be advisable.

"Free CD contains several real and artificial data sets used in the book in SPSS, SYSTAT, and ASCII formats"--Cover

Design for Manufacturability and Statistical Design: A Comprehensive Approach presents a comprehensive overview of methods that need to be mastered in understanding state-of-the-art design for manufacturability and statistical design methodologies. Broadly, design for manufacturability is a set of techniques that attempt to fix the systematic sources of variability, such as those due to photolithography and CMP. Statistical design, on the other hand, deals with the random sources of variability. Both paradigms operate within a common framework, and their joint comprehensive treatment is one of the objectives of this book and an important differentation.

Provides an introduction to the diverse subject area of experimental design, with many practical and applicable exercises to help the reader understand, present and analyse the data. The pragmatic approach offers technical training for use of designs and teaches statistical and non-statistical skills in design and analysis of project studies throughout science and industry. - Provides an introduction to the diverse subject area of experimental design and includes practical and applicable exercises to help understand, present and analyse the data - Offers technical training for use of designs and teaches statistical and non-statistical skills in design and analysis of project studies throughout science and industry - Discusses one-factor designs and blocking designs, factorial experimental designs, Taguchi methods and response surface methods, among other topics

Fully updated, this revised edition describes the statistical aspects of both the design and analysis of trials, with particular emphasis on the more recent methods of analysis.About 8000 clinical trials are undertaken annually in all areas of medicine, from the treatment of acne to the prevention of cancer. Correct interpretation of the data from such trials depends largely on adequate design and on performing the appropriate statistical analyses. This book provides a useful guide to medical statisticians and others faced with the often difficult problems of designing and analysing clinical trials./a