Spike Timing

Spike Timing
Author :
Publisher : CRC Press
Total Pages : 425
Release :
ISBN-10 : 9781439838150
ISBN-13 : 1439838151
Rating : 4/5 (50 Downloads)

Synopsis Spike Timing by : Patricia M. DiLorenzo

Neuronal communication forms the basis for all behavior, from the smallest movement to our grandest thought processes. Among the many mechanisms that support these functions, spike timing is among the most powerful and—until recently—perhaps the least studied. In the last two decades, however, the study of spike timing has exploded. The heightened interest is due to several factors. These include the development of physiological tools for measuring the activity of neural ensembles and analytical tools for assessing and characterizing spike timing. These advances are coupled with a growing appreciation of spike timing’s theoretical importance for the design principles of the brain. Spike Timing: Mechanisms and Function examines the function of spike timing in sensory, motor, and integrative processes, providing readers with a broad perspective on how spike timing is produced and used by the nervous system. It brings together the work and ideas of leaders in the field to address current thinking as well as future possibilities. The first section of the book describes the foundation for quantitative analysis and theory. It examines the information contained in spike timing, how it can be quantified, and how neural systems can extract it. The second section explores how input-output relationships are reflected in spike timing across a range of sensory systems. Drawing together multiple perspectives, including theoretical and computational studies as well as experimental studies in a range of model systems, the book provides a firm background for investigators to consider spike timing as it applies to their own work. It also offers a glimpse of future advances related to mechanisms of spike timing and its role in neural function, such as the development of novel computational technologies.

Neuronal Dynamics

Neuronal Dynamics
Author :
Publisher : Cambridge University Press
Total Pages : 591
Release :
ISBN-10 : 9781107060838
ISBN-13 : 1107060834
Rating : 4/5 (38 Downloads)

Synopsis Neuronal Dynamics by : Wulfram Gerstner

This solid introduction uses the principles of physics and the tools of mathematics to approach fundamental questions of neuroscience.

Spike-timing dependent plasticity

Spike-timing dependent plasticity
Author :
Publisher : Frontiers E-books
Total Pages : 575
Release :
ISBN-10 : 9782889190430
ISBN-13 : 2889190439
Rating : 4/5 (30 Downloads)

Synopsis Spike-timing dependent plasticity by : Henry Markram

Hebb's postulate provided a crucial framework to understand synaptic alterations underlying learning and memory. Hebb's theory proposed that neurons that fire together, also wire together, which provided the logical framework for the strengthening of synapses. Weakening of synapses was however addressed by "not being strengthened", and it was only later that the active decrease of synaptic strength was introduced through the discovery of long-term depression caused by low frequency stimulation of the presynaptic neuron. In 1994, it was found that the precise relative timing of pre and postynaptic spikes determined not only the magnitude, but also the direction of synaptic alterations when two neurons are active together. Neurons that fire together may therefore not necessarily wire together if the precise timing of the spikes involved are not tighly correlated. In the subsequent 15 years, Spike Timing Dependent Plasticity (STDP) has been found in multiple brain brain regions and in many different species. The size and shape of the time windows in which positive and negative changes can be made vary for different brain regions, but the core principle of spike timing dependent changes remain. A large number of theoretical studies have also been conducted during this period that explore the computational function of this driving principle and STDP algorithms have become the main learning algorithm when modeling neural networks. This Research Topic will bring together all the key experimental and theoretical research on STDP.

The Spike

The Spike
Author :
Publisher : Princeton University Press
Total Pages : 232
Release :
ISBN-10 : 9780691213514
ISBN-13 : 0691213518
Rating : 4/5 (14 Downloads)

Synopsis The Spike by : Mark Humphries

The story of a neural impulse and what it reveals about how our brains work We see the last cookie in the box and think, can I take that? We reach a hand out. In the 2.1 seconds that this impulse travels through our brain, billions of neurons communicate with one another, sending blips of voltage through our sensory and motor regions. Neuroscientists call these blips “spikes.” Spikes enable us to do everything: talk, eat, run, see, plan, and decide. In The Spike, Mark Humphries takes readers on the epic journey of a spike through a single, brief reaction. In vivid language, Humphries tells the story of what happens in our brain, what we know about spikes, and what we still have left to understand about them. Drawing on decades of research in neuroscience, Humphries explores how spikes are born, how they are transmitted, and how they lead us to action. He dives into previously unanswered mysteries: Why are most neurons silent? What causes neurons to fire spikes spontaneously, without input from other neurons or the outside world? Why do most spikes fail to reach any destination? Humphries presents a new vision of the brain, one where fundamental computations are carried out by spontaneous spikes that predict what will happen in the world, helping us to perceive, decide, and react quickly enough for our survival. Traversing neuroscience’s expansive terrain, The Spike follows a single electrical response to illuminate how our extraordinary brains work.

Memristor and Memristive Neural Networks

Memristor and Memristive Neural Networks
Author :
Publisher : BoD – Books on Demand
Total Pages : 326
Release :
ISBN-10 : 9789535139478
ISBN-13 : 9535139479
Rating : 4/5 (78 Downloads)

Synopsis Memristor and Memristive Neural Networks by : Alex James

This book covers a range of models, circuits and systems built with memristor devices and networks in applications to neural networks. It is divided into three parts: (1) Devices, (2) Models and (3) Applications. The resistive switching property is an important aspect of the memristors, and there are several designs of this discussed in this book, such as in metal oxide/organic semiconductor nonvolatile memories, nanoscale switching and degradation of resistive random access memory and graphene oxide-based memristor. The modelling of the memristors is required to ensure that the devices can be put to use and improve emerging application. In this book, various memristor models are discussed, from a mathematical framework to implementations in SPICE and verilog, that will be useful for the practitioners and researchers to get a grounding on the topic. The applications of the memristor models in various neuromorphic networks are discussed covering various neural network models, implementations in A/D converter and hierarchical temporal memories.

Inhibitory Synaptic Plasticity

Inhibitory Synaptic Plasticity
Author :
Publisher : Springer Science & Business Media
Total Pages : 191
Release :
ISBN-10 : 9781441969781
ISBN-13 : 1441969780
Rating : 4/5 (81 Downloads)

Synopsis Inhibitory Synaptic Plasticity by : Melanie A. Woodin

This volume will explore the most recent findings on cellular mechanisms of inhibitory plasticity and its functional role in shaping neuronal circuits, their rewiring in response to experience, drug addiction and in neuropathology. Inhibitory Synaptic Plasticity will be of particular interest to neuroscientists and neurophysiologists.

23 Problems in Systems Neuroscience

23 Problems in Systems Neuroscience
Author :
Publisher : Oxford University Press
Total Pages : 531
Release :
ISBN-10 : 9780195148220
ISBN-13 : 0195148223
Rating : 4/5 (20 Downloads)

Synopsis 23 Problems in Systems Neuroscience by : Jan Leonard Hemmen

The complexity of the brain and the protean nature of behavior remain the most elusive area of science, but also the most important. van Hemmen and Sejnowski invited 23 experts from the many areas--from evolution to qualia--of systems neuroscience to formulate one problem each. Although each chapter was written independently and can be read separately, together they provide a useful roadmap to the field of systems neuroscience and will serve as a source of inspirations for future explorers of the brain.

Synaptic Plasticity in the Hippocampus

Synaptic Plasticity in the Hippocampus
Author :
Publisher : Springer Science & Business Media
Total Pages : 219
Release :
ISBN-10 : 9783642732027
ISBN-13 : 364273202X
Rating : 4/5 (27 Downloads)

Synopsis Synaptic Plasticity in the Hippocampus by : Helmut L. Haas

This is the second time that I have had the honor of opening an interna tional symposium dedicated to the functions of the hippocampus here in Pecs. It was a pleasure to greet the participants in the hope that their valuable contributions will make this meeting a tradition in this town. As one of the hosts of the symposium, I had the sorrowful duty to remind you of the absence of a dear colleague, Professor Graham God dard. His tragic and untimely death represents the irreparable loss of both a friend and an excellent researcher. This symposium is dedicated to his memory. If I compare the topics of the lectures of this symposium with those of the previous one, a striking difference becomes apparent. A dominating tendency of the previous symposium was to attempt to define hippocam pal function or to offer data relevant to supporting or rejecting existing theoretical positions. No such tendency is reflected in the titles of the present symposium, in which most of the contributions deal with hip pocampal phenomena at the most elementary level. Electrical, biochemi cal, biophysical, and pharmacological events at the synaptic, membrane, or intracellular level are analyzed without raising the question of what kind of integral functions these elementary phenomena are a part of.

Spikes

Spikes
Author :
Publisher : MIT Press (MA)
Total Pages : 418
Release :
ISBN-10 : 0262181746
ISBN-13 : 9780262181747
Rating : 4/5 (46 Downloads)

Synopsis Spikes by : Fred Rieke

Intended for neurobiologists with an interest in mathematical analysis of neural data as well as the growing number of physicists and mathematicians interested in information processing by "real" nervous systems, Spikes provides a self-contained review of relevant concepts in information theory and statistical decision theory.