Teaches Students How to Perform Spatio-Temporal Analyses within Epidemiological StudiesSpatio-Temporal Methods in Environmental Epidemiology is the first book of its kind to specifically address the interface between environmental epidemiology and spatio-temporal modeling. In response to the growing need for collaboration between statisticians and

Spatio-Temporal Methods in Environmental Epidemiology with R, like its First Edition, explores the interface between environmental epidemiology and spatio-temporal modeling. It links recent developments in spatio-temporal theory with epidemiological applications. Drawing on real-life problems, it shows how recent advances in methodology can assess the health risks associated with environmental hazards. The book's clear guidelines enable the implementation of the methodology and estimation of risks in practice. New additions to the Second Edition include: a thorough exploration of the underlying concepts behind knowledge discovery through data; a new chapter on extracting information from data using R and the tidyverse; additional material on methods for Bayesian computation, including the use of NIMBLE and Stan; new methods for performing spatio-temporal analysis and an updated chapter containing further topics. Throughout the book there are new examples, and the presentation of R code for examples has been extended. Along with these additions, the book now has a GitHub site (https://spacetime-environ.github.io/stepi2) that contains data, code and further worked examples. Features: • Explores the interface between environmental epidemiology and spatio­-temporal modeling • Incorporates examples that show how spatio-temporal methodology can inform societal concerns about the effects of environmental hazards on health • Uses a Bayesian foundation on which to build an integrated approach to spatio-temporal modeling and environmental epidemiology • Discusses data analysis and topics such as data visualization, mapping, wrangling and analysis • Shows how to design networks for monitoring hazardous environmental processes and the ill effects of preferential sampling • Through the listing and application of code, shows the power of R, tidyverse, NIMBLE and Stan and other modern tools in performing complex data analysis and modeling Representing a continuing important direction in environmental epidemiology, this book – in full color throughout – underscores the increasing need to consider dependencies in both space and time when modeling epidemiological data. Readers will learn how to identify and model patterns in spatio-temporal data and how to exploit dependencies over space and time to reduce bias and inefficiency when estimating risks to health.

The world is becoming increasingly complex, with larger quantities of data available to be analyzed. It so happens that much of these "big data" that are available are spatio-temporal in nature, meaning that they can be indexed by their spatial locations and time stamps. Spatio-Temporal Statistics with R provides an accessible introduction to statistical analysis of spatio-temporal data, with hands-on applications of the statistical methods using R Labs found at the end of each chapter. The book: Gives a step-by-step approach to analyzing spatio-temporal data, starting with visualization, then statistical modelling, with an emphasis on hierarchical statistical models and basis function expansions, and finishing with model evaluation Provides a gradual entry to the methodological aspects of spatio-temporal statistics Provides broad coverage of using R as well as "R Tips" throughout. Features detailed examples and applications in end-of-chapter Labs Features "Technical Notes" throughout to provide additional technical detail where relevant Supplemented by a website featuring the associated R package, data, reviews, errata, a discussion forum, and more The book fills a void in the literature and available software, providing a bridge for students and researchers alike who wish to learn the basics of spatio-temporal statistics. It is written in an informal style and functions as a down-to-earth introduction to the subject. Any reader familiar with calculus-based probability and statistics, and who is comfortable with basic matrix-algebra representations of statistical models, would find this book easy to follow. The goal is to give as many people as possible the tools and confidence to analyze spatio-temporal data.

In the field of environmental epidemiology, there is a great deal of care required in constructing models that accurately estimate the effects of environmental exposures on human health. This is because the nature of the data that is available to researchers to estimate these effects is almost always observational in nature, making it difficult to adequately control for all potential confounders - both measured and unmeasured. Here, we tackle three different problems in which the goal is to accurately estimate the effect of an environmental exposure on various health outcomes.

As an area of statistical application, environmental epidemiology and more speci cally, the estimation of health risk associated with the exposure to - vironmental agents, has led to the development of several statistical methods and software that can then be applied to other scienti c areas. The stat- tical analyses aimed at addressing questions in environmental epidemiology have the following characteristics. Often the signal-to-noise ratio in the data is low and the targets of inference are inherently small risks. These constraints typically lead to the development and use of more sophisticated (and pot- tially less transparent) statistical models and the integration of large hi- dimensional databases. New technologies and the widespread availability of powerful computing are also adding to the complexities of scienti c inves- gation by allowing researchers to t large numbers of models and search over many sets of variables. As the number of variables measured increases, so do the degrees of freedom for in uencing the association between a risk factor and an outcome of interest. We have written this book, in part, to describe our experiences developing and applying statistical methods for the estimation for air pollution health e ects. Our experience has convinced us that the application of modern s- tistical methodology in a reproducible manner can bring to bear subst- tial bene ts to policy-makers and scientists in this area. We believe that the methods described in this book are applicable to other areas of environmental epidemiology, particularly those areas involving spatial{temporal exposures.

Handbook of Spatial Epidemiology explains how to model epidemiological problems and improve inference about disease etiology from a geographical perspective. Top epidemiologists, geographers, and statisticians share interdisciplinary viewpoints on analyzing spatial data and space-time variations in disease incidences. These analyses can provide imp

Spatiotemporal Environmental Health Modelling: A Tractatus Stochasticus provides a holistic, conceptual and quantitative framework for Environmental Health Modelling in space-time. The holistic framework integrates two aspects of Environmental Health Science that have been previously treated separately: the environmental aspect, which involves the natural processes that bring about human exposure to harmful substances; and the health aspect, which focuses on the interactions of these substances with the human body. Some of the fundamental issues addressed in this work include variability, scale, uncertainty, and space-time connectivity. These topics are important in the characterization of natural systems and health processes. Spatiotemporal Environmental Health Modelling: A Tractatus Stochasticus explains why modern stochastics is the appropriate mechanical vehicle for addressing such issues in a rigorous way. In particular, modern stochastics incorporates concepts and methods from probability, classical statistics, geostatistics, statistical mechanics and field theory. The authors present a synthetic view of environmental health that embraces all of the various components and focuses on their mutual interactions. Spatiotemporal Environmental Health Modeling: A Tractatus Stochasticus includes new material on Bayesian maximum entropy estimation techniques and space-time random field estimation methods. The authors show why these methods have clear advantages over the classical geostatistical estimation procedures and how they can be used to provide accurate space-time maps of environmental health processes. Also included are expositions of diagrammatic perturbation and renormalization group analysis, which have not been previously discussed within the context of Environmental Health. Finally, the authors present stochastic indicators that can be used for large-scale characterization of contamination and investigations of health effects at the microscopic level. This book will be a useful reference to both researchers and practitioners of Environmental Health Sciences. It will appeal specifically to environmental engineers, geographers, geostatisticians, earth scientists, toxicologists, epidemiologists, pharmacologists, applied mathematicians, physicists and biologists.

Winner of the 2013 DeGroot Prize. A state-of-the-art presentation of spatio-temporal processes, bridging classic ideas with modern hierarchical statistical modeling concepts and the latest computational methods Noel Cressie and Christopher K. Wikle, are also winners of the 2011 PROSE Award in the Mathematics category, for the book “Statistics for Spatio-Temporal Data” (2011), published by John Wiley and Sons. (The PROSE awards, for Professional and Scholarly Excellence, are given by the Association of American Publishers, the national trade association of the US book publishing industry.) Statistics for Spatio-Temporal Data has now been reprinted with small corrections to the text and the bibliography. The overall content and pagination of the new printing remains the same; the difference comes in the form of corrections to typographical errors, editing of incomplete and missing references, and some updated spatio-temporal interpretations. From understanding environmental processes and climate trends to developing new technologies for mapping public-health data and the spread of invasive-species, there is a high demand for statistical analyses of data that take spatial, temporal, and spatio-temporal information into account. Statistics for Spatio-Temporal Data presents a systematic approach to key quantitative techniques that incorporate the latest advances in statistical computing as well as hierarchical, particularly Bayesian, statistical modeling, with an emphasis on dynamical spatio-temporal models. Cressie and Wikle supply a unique presentation that incorporates ideas from the areas of time series and spatial statistics as well as stochastic processes. Beginning with separate treatments of temporal data and spatial data, the book combines these concepts to discuss spatio-temporal statistical methods for understanding complex processes. Topics of coverage include: Exploratory methods for spatio-temporal data, including visualization, spectral analysis, empirical orthogonal function analysis, and LISAs Spatio-temporal covariance functions, spatio-temporal kriging, and time series of spatial processes Development of hierarchical dynamical spatio-temporal models (DSTMs), with discussion of linear and nonlinear DSTMs and computational algorithms for their implementation Quantifying and exploring spatio-temporal variability in scientific applications, including case studies based on real-world environmental data Throughout the book, interesting applications demonstrate the relevance of the presented concepts. Vivid, full-color graphics emphasize the visual nature of the topic, and a related FTP site contains supplementary material. Statistics for Spatio-Temporal Data is an excellent book for a graduate-level course on spatio-temporal statistics. It is also a valuable reference for researchers and practitioners in the fields of applied mathematics, engineering, and the environmental and health sciences.

This handbook focuses on the enormous literature applying statistical methodology and modelling to environmental and ecological processes. The 21st century statistics community has become increasingly interdisciplinary, bringing a large collection of modern tools to all areas of application in environmental processes. In addition, the environmental community has substantially increased its scope of data collection including observational data, satellite-derived data, and computer model output. The resultant impact in this latter community has been substantial; no longer are simple regression and analysis of variance methods adequate. The contribution of this handbook is to assemble a state-of-the-art view of this interface. Features: An internationally regarded editorial team. A distinguished collection of contributors. A thoroughly contemporary treatment of a substantial interdisciplinary interface. Written to engage both statisticians as well as quantitative environmental researchers. 34 chapters covering methodology, ecological processes, environmental exposure, and statistical methods in climate science.