Small Molecule Based Fluorescent Molecular Probes For Facilitating Biomedical Research
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Author |
: Chris D. Geddes |
Publisher |
: Springer Science & Business Media |
Total Pages |
: 333 |
Release |
: 2007-05-24 |
ISBN-10 |
: 9780387233352 |
ISBN-13 |
: 0387233350 |
Rating |
: 4/5 (52 Downloads) |
Synopsis Advanced Concepts in Fluorescence Sensing by : Chris D. Geddes
Over the last decade, fluorescence has become the dominant tool in biotechnology and medical imaging. These exciting advances have been underpinned by the advances in time-resolved techniques and instrumentation, probe design, chemical / biochemical sensing, coupled with our furthered knowledge in biology. Complementary volumes 9 and 10, Advanced Concepts of Fluorescence Sensing: Small Molecule Sensing and Advanced Concepts of Fluorescence Sensing: Macromolecular Sensing, aim to summarize the current state of the art in fluorescent sensing. For this reason, Drs. Geddes and Lakowicz have invited chapters, encompassing a broad range of fluorescence sensing techniques. Some chapters deal with small molecule sensors, such as for anions, cations, and CO2, while others summarize recent advances in protein-based and macromolecular sensors. The Editors have, however, not included DNA or RNA based sensing in this volume, as this were reviewed in Volume 7 and is to be the subject of a more detailed volume in the near future.
Author |
: Sebastian Dekkers |
Publisher |
: |
Total Pages |
: |
Release |
: 2019 |
ISBN-10 |
: OCLC:1127089020 |
ISBN-13 |
: |
Rating |
: 4/5 (20 Downloads) |
Synopsis Small Molecule-based Fluorescent Probes as Tool Compounds for Chemokine Receptors CXCR4 and ACKR3 by : Sebastian Dekkers
Author |
: Yinhuan Xie |
Publisher |
: |
Total Pages |
: |
Release |
: 2020 |
ISBN-10 |
: OCLC:1255635151 |
ISBN-13 |
: |
Rating |
: 4/5 (51 Downloads) |
Synopsis Substrate-based Small Molecule Ratiometric Fluorescent Probes by : Yinhuan Xie
Author |
: Erwin J. G. Peterman |
Publisher |
: Humana Press |
Total Pages |
: 317 |
Release |
: 2011-09-15 |
ISBN-10 |
: 1617792810 |
ISBN-13 |
: 9781617792816 |
Rating |
: 4/5 (10 Downloads) |
Synopsis Single Molecule Analysis by : Erwin J. G. Peterman
Life scientists believe that life is driven, directed, and shaped by biomolecules working on their own or in concert. It is only in the last few decades that technological breakthroughs in sensitive fluorescence microscopy and single-molecule manipulation techniques have made it possible to observe and manipulate single biomolecules and measure their individual properties. The methodologies presented in Single Molecule Techniques: Methods and Protocols are being applied more and more to the study of biologically relevant molecules, such as DNA, DNA-binding proteins, and motor proteins, and are becoming commonplace in molecular biophysics, biochemistry, and molecular and cell biology. The aim of Single Molecule Techniques: Methods and Protocols is to provide a broad overview of single-molecule approaches applied to biomolecules on the basis of clear and concise protocols, including a solid introduction to the most widely used single-molecule techniques, such as optical tweezers, single-molecule fluorescence tools, atomic force microscopy, magnetic tweezers, and tethered particle motion. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Single Molecule Techniques: Methods and Protocols serves as an ideal guide to scientists of all backgrounds and provides a broad and thorough overview of the exciting and still-emerging field of single-molecule biology.
Author |
: Youngjun Lee |
Publisher |
: Springer Theses |
Total Pages |
: 216 |
Release |
: 2019-09-11 |
ISBN-10 |
: 9811346607 |
ISBN-13 |
: 9789811346606 |
Rating |
: 4/5 (07 Downloads) |
Synopsis Systematic Exploration of Indolizine-Based Small Fluorescent Molecules by : Youngjun Lee
This thesis describes an in-depth study of an indolizine-based fluorophore, from understanding of its structure-photophysical property relationship to its application as a useful biological reporter. Organic fluorophores have been extensively used in the field of molecular biology owing to their excellent photophysical property, suitable cell permeability, and synthetic flexibility. Understanding of the structure-photophysical property relationship of a given fluorophore often paves the road to the development of valuable molecular probes to visualize and transcribe biological networks. In this thesis, respective chapters deal with molecular design, organic synthesis, structure-property analysis, and quantum-mechanical interpretation of unexplored family of indolizine-based molecules. This systematic exploration has led to rational development of a new microalgae lipid droplet probe, colorful bioorthogonal fluorogenic probes, and a bright mitochondrial probe, working under live cell conditions. Harnessing the optical properties of a given fluorophore has been an important topic for a couple of decades, both in industry and in academia. This thesis provides useful insights for the improvement and development of unique small fluorescent materials, or optical materials.
Author |
: Paul R. Selvin |
Publisher |
: CSHL Press |
Total Pages |
: 511 |
Release |
: 2008 |
ISBN-10 |
: 9780879697754 |
ISBN-13 |
: 087969775X |
Rating |
: 4/5 (54 Downloads) |
Synopsis Single-molecule Techniques by : Paul R. Selvin
Geared towards research scientists in structural and molecular biology, biochemistry, and biophysics, this manual will be useful to all who are interested in observing, manipulating and elucidating the molecular mechanisms and discrete properties of macromolecules.
Author |
: Richard P. Haugland |
Publisher |
: |
Total Pages |
: 966 |
Release |
: 2002 |
ISBN-10 |
: 0971063613 |
ISBN-13 |
: 9780971063617 |
Rating |
: 4/5 (13 Downloads) |
Synopsis Handbook of Fluorescent Probes and Research Products by : Richard P. Haugland
Author |
: Hao Li |
Publisher |
: |
Total Pages |
: |
Release |
: 2017 |
ISBN-10 |
: OCLC:1078222449 |
ISBN-13 |
: |
Rating |
: 4/5 (49 Downloads) |
Synopsis Development of Small Molecule Probes for Fluorescence and Photoacoustic Molecular Imaging by : Hao Li
Author |
: James Edward Egleton |
Publisher |
: |
Total Pages |
: |
Release |
: 2015 |
ISBN-10 |
: OCLC:1064572644 |
ISBN-13 |
: |
Rating |
: 4/5 (44 Downloads) |
Synopsis Small Molecule Colorimetric and Fluorescent Probes for Specific Protein Detection by : James Edward Egleton
Author |
: Anthony W. Czarnik |
Publisher |
: |
Total Pages |
: 256 |
Release |
: 1993 |
ISBN-10 |
: UOM:39015031786281 |
ISBN-13 |
: |
Rating |
: 4/5 (81 Downloads) |
Synopsis Fluorescent Chemosensors for Ion and Molecule Recognition by : Anthony W. Czarnik
From an August 1992 symposium in Washington, D.C., 13 papers report on research into developing fluorescent chemosensors for devices to monitor several critical parameters of blood composition in real time. They aim at opening communication between the clinicians and researchers who want such devices and the scientists and engineers who could develop them. Among the topics are the synthesis and study of crown ethers with alkali- metal-enhanced fluorescence, the tunable florescence of some macrocyclic anthracenophanes, and fluorescent probes in studies of proteases. Annotation copyright by Book News, Inc., Portland, OR