Single Subject Designs in Biomedicine draws upon the rich history of single case research within the educational and behavioral research settings and extends the application to the field of biomedicine. Biomedical illustrations are used to demonstrate the processes of designing, implementing, and evaluating a single subject design. Strengths and limitations of various methodologies are presented, along with specific clinical areas of application in which these applications would be appropriate. Statistical and visual techniques for data analysis are also discussed. The breadth and depth of information provided is suitable for medical students in research oriented courses, primary care practitioners and medical specialists seeking to apply methods of evidence practice to improve patient care, and medical researchers who are expanding their methodological expertise to include single subject designs. Increasing awareness of the utility in the single subject design could enhance treatment approach and evaluation both in biomedical research and medical care settings.

This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.

Used as both a core textbook in PT programs and as a clinical reference, Physical Therapy for Children, 4th Edition, provides the essential information needed by PTs, both student and professional, when working with children. Like the previous bestselling editions, the 4th edition follows the practice pattern categories of the Guide to Physical Therapist Practice and uses the IFC model of the disabling process as it presents up-to-date evidence-based coverage of treatment. In this latest edition, Suzann Campbell DeLapp, Robert J. Palisano, and Margo N. Orlin have added more case studies and video clips, additional chapters and Medline-linked references online, and Evidence to Practice boxes to make it easy to find and remember important information. Provides comprehensive foundational knowledge in decision making, screening, development, motor control, and motor learning, the impairments of body function and structure, and the PT management of pediatric disorders. Reflects a family-centered care model throughout to help you understand how to involve children and their caregivers in developing and implementing intervention plans. Emphasizes an evidence-based approach that incorporates the latest research for the best outcomes. Follows the practice pattern guidelines of the Guide to Physical Therapist Practice, 2nd Edition which sets the standard for physical therapy practice. Features the International Classification of Function, Disability, and Health (ICF) of the World Health Organization (WHO) as the model for the disabling process, emphasizing activity rather than functional limitations and participation rather than disability in keeping with the book’s focus on prevention of disability. Provides extensive case studies that show the practical application of material covered in the text and are often accompanied by online video clips illustrating the condition and its management. Makes it easy to access key information with plenty of tables and boxes that organize and summarize important points. Clearly demonstrates important concepts and clinical conditions you’ll encounter in practice with over 800 illustrations. Takes learning to a deeper level with additional resources on the Evolve website featuring: Over 40 video clips that correspond to case studies and demonstrate conditions found in each chapter Helpful resources, including web links Questions and exercises you’ll find helpful when preparing for the pediatric specialist certification exam

Web-based applications provide the power of desktop and server applications with the exibility and accessibility of the web. Using web browsers, users can securely access applications from anywhere within the reach of the company intranet or extranet. The special issue strives to explore the advanced web-based information systems and database applications in healthcare area. Healthcare organizations are undergoing major reorganizations and adjustments to meet the increasing demands of improved healthcare access and quality, as well as lowered costs. As the use of information technology to process medical data increases, much of the critical information necessary to meet these challenges is being stored in digital format. Web-enabled information technologies can provide the means for greater access and more effective integration of healthcare information from disparate computer applications and other information resources. This book presents studies from leading researchers and practitioners focusing on the current challenges, directions, trends, and opportunities associated with heal- care organizations and their strategic use of web-enabled technologies. Managing healthcare information systems with web-enabled technologies is an excellent ve- cle for understanding current and potential uses of Internet technology in the broad areas of healthcare and medical applications.

Addressing the sleep difficulties prevalent amongst people with Autism Spectrum Disorders (ASD), this accessible book discusses in depth, covers a broad range of sleep disorders and presents proven remedies and treatment regimes. Original.

This book constitutes the thoroughly refereed post-conference proceedings of the 5th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2012, held in Vilamoura, Portugal, in February 2012. The 26 revised full papers presented together with one invited lecture were carefully reviewed and selected from a total of 522 submissions. The papers cover a wide range of topics and are organized in four general topical sections on biomedical electronics and devices; bioinformatics models, methods and algorithms; bio-inspired systems and signal processing; health informatics.

Principles of Research Methodology: A Guide for Clinical Investigators is the definitive, comprehensive guide to understanding and performing clinical research. Designed for medical students, physicians, basic scientists involved in translational research, and other health professionals, this indispensable reference also addresses the unique challenges and demands of clinical research and offers clear guidance in becoming a more successful member of a medical research team and critical reader of the medical research literature. The book covers the entire research process, beginning with the conception of the research problem to publication of findings. Principles of Research Methodology: A Guide for Clinical Investigators comprehensively and concisely presents concepts in a manner that is relevant and engaging to read. The text combines theory and practical application to familiarize the reader with the logic of research design and hypothesis construction, the importance of research planning, the ethical basis of human subjects research, the basics of writing a clinical research protocol and scientific paper, the logic and techniques of data generation and management, and the fundamentals and implications of various sampling techniques and alternative statistical methodologies. Organized in thirteen easy to read chapters, the text emphasizes the importance of clearly-defined research questions and well-constructed hypothesis (reinforced throughout the various chapters) for informing methods and in guiding data interpretation. Written by prominent medical scientists and methodologists who have extensive personal experience in biomedical investigation and in teaching key aspects of research methodology to medical students, physicians and other health professionals, the authors expertly integrate theory with examples and employ language that is clear and useful for a general medical audience. A major contribution to the methodology literature, Principles of Research Methodology: A Guide for Clinical Investigators is an authoritative resource for all individuals who perform research, plan to perform it, or wish to understand it better.

This book is a practical guide to help researchers draw valid causal inferences from small-scale clinical intervention studies. It should be of interest to teachers of, and students in, courses with an experimental clinical component, as well as clinical researchers. Inferential statistics used in the analysis of group data are frequently invalid for use with data from single-case experimental designs. Even non-parametric rank tests provide, at best, approximate solutions for only some single-case (and small-n ) designs. Randomization (Exact) tests, on the other hand, can provide valid statistical analyses for all designs that incorporate a random procedure for assigning treatments to subjects or observation periods, including single-case designs. These Randomization tests require large numbers of data rearrangements and have been seldom used, partly because desktop computers have only recently become powerful enough to complete the analyses in a reasonable time. Now that the necessary computational power is available, they continue to be under-used because they receive scant attention in standard statistical texts for behavioral researchers and because available programs for running the analyses are relatively inaccessible to researchers with limited statistical or computing interest. This book is first and foremost a practical guide, although it also presents the theoretical basis for Randomization tests. Its most important aim is to make these tests accessible to researchers for a wide range of designs. It does this by providing programs on CD-ROM that allow users to run analyses of their data within a standard package (Minitab, Excel, or SPSS) with which they are already familiar. No statistical or computing expertise is required to use these programs. This is the "new stats" for single-case and small-n intervention studies, and anyone interested in this research approach will benefit.

"In this chapter you will learn how to measure target behaviors and use Excel or other software to record and edit client data. You will then be able to import these data into R and use the SSD for R functions to analyze them. The first part of this chapter will focus on the types of data you will want to record and some common issues related to collecting these. While an overview of this material is covered in this chapter, additional resources that include these topics in-depth are listed in Appendix D. The second part of this chapter will show you how to use Excel or another spreadsheet program to quickly and effectively record these data"--

Become a successful evidence-based practitioner. How do you evaluate the evidence? Is the information accurate, relevant and meaningful for clinical decision making? Did the design fit the research questions and was the analysis and interpretation of data appropriate? Here are all the materials you need to take your first steps as evidence-based practitioners…how to use the design, data and analysis of research as the foundation for effective clinical decision making. You’ll find support every step of the way as you progress from the foundations of clinical research and concepts of measurement through the processes of designing studies and analyzing data to writing their own research proposal.