RNAs form complexes with proteins and other RNAs. The RNA‐infrastructure represents the spatiotemporal interaction of these proteins and RNAs in a cell‐wide network. RNA Infrastructure and Networks brings together these ideas to illustrate the scope of RNA‐based biology, and how connecting RNA mechanisms is a powerful tool to investigate regulatory pathways. This book is but a taste of the wide range of RNA‐based mechanisms that connect in the RNA infrastructure.

A comprehensive, authoritative look at an emergent area in post-genomic science, Evolutionary genomics is an up-and-coming, complex field that attempts to explain the biocomplexity of the living world. Evolutionary Genomics and Systems Biology is the first full-length book to blend established and emerging concepts in bioinformatics, evolution, genomics, and structural biology, with the integrative views of network and systems biology. Three key aspects of evolutionary genomics and systems biology are covered in clear detail: the study of genomic history, i.e., understanding organismal evolution at the genomic level; the study of macromolecular complements, which encompasses the evolution of the protein and RNA machinery that propels life; and the evolutionary and dynamic study of wiring diagrams—macromolecular components in interaction—in the context of genomic complements. The book also features: A solid, comprehensive treatment of phylogenomics, the evolution of genomes, and the evolution of biological networks, within the framework of systems biology A special section on RNA biology—translation, evolution of structure, and micro RNA and regulation of gene expression Chapters on the mapping of genotypes to phenotypes, the role of information in biology, protein architecture and biological function, chromosomal rearrangements, and biological networks and disease Contributions by leading authorities on each topic Evolutionary Genomics and Systems Biology is an ideal book for students and professionals in genomics, bioinformatics, evolution, structural biology, complexity, origins of life, systematic biology, and organismal diversity, as well as those individuals interested in aspects of biological sciences as they interface with chemistry, physics, and computer science and engineering.

InfoWorld is targeted to Senior IT professionals. Content is segmented into Channels and Topic Centers. InfoWorld also celebrates people, companies, and projects.

This book provides an entry point into Systems Biology for researchers in genetics, molecular biology, cell biology, microbiology and biomedical science to understand the key concepts to expanding their work. Chapters organized around broader themes of Organelles and Organisms, Systems Properties of Biological Processes, Cellular Networks, and Systems Biology and Disease discuss the development of concepts, the current applications, and the future prospects. Emphasis is placed on concepts and insights into the multi-disciplinary nature of the field as well as the importance of systems biology in human biological research. Technology, being an extremely important aspect of scientific progress overall, and in the creation of new fields in particular, is discussed in 'boxes' within each chapter to relate to appropriate topics. - 2013 Honorable Mention for Single Volume Reference in Science from the Association of American Publishers' PROSE Awards - Emphasizes the interdisciplinary nature of systems biology with contributions from leaders in a variety of disciplines - Includes the latest research developments in human and animal models to assist with translational research - Presents biological and computational aspects of the science side-by-side to facilitate collaboration between computational and biological researchers

Clouds are being positioned as the next-generation consolidated, centralized, yet federated IT infrastructure for hosting all kinds of IT platforms and for deploying, maintaining, and managing a wider variety of personal, as well as professional applications and services. Handbook of Research on Cloud Infrastructures for Big Data Analytics focuses exclusively on the topic of cloud-sponsored big data analytics for creating flexible and futuristic organizations. This book helps researchers and practitioners, as well as business entrepreneurs, to make informed decisions and consider appropriate action to simplify and streamline the arduous journey towards smarter enterprises.

An all-encompassing coverage on UMTS Networks including an in-depth discussion of current work on UMTS evolution and 4G . UMTS Networks and Beyond offers a comprehensive introduction to the networking aspects of UMTS and the networks coming after UMTS. The book is unique in that it systematically compares how a particular problem, e.g. obtaining connectivity, is solved in UMTS and how the same problem is solved in a Computer Network such as the Internet. It also highlights why the respective solutions are so different. The first part of the book provides a detailed technical discussion of UMTS, including original vision, architecture, protocol stacks and overall functionality. It places UMTS in the context of its evolution of from GSM and its convergence with Computer Networks. The second part of the book discusses today’s vision of 4G, and introduces upcoming networking technologies. Emphasis is on LTE / SAE as successor of UMTS; UMB, WiMAX and NGN are also discussed. The book gives an overview of what these technologies are likely to offer, of their architectures, protocols and functionality. It also discusses their differences and similarities, and whether they will qualify as 4G. Key Features: Provides readers, particularly those with a background in IP-based networks, with a technical understanding of what UMTS does, how it works and how it is likely to evolve Explains the differences in design between UMTS Networks and Computer Networks and discusses how these design divergences can be reconciled in the future Shows how economic considerations shape the design of UMTS Motivates why particular design choices are made in UMTS Gives an in-depth introduction to LTE / SAE Provides a detailed picture of the state of the art in 4G Illustrates the theory with numerous tables and figures This comprehensive textbook is essential reading for advanced students and lecturers in communications systems and networking. It is also of interest to engineers and researchers in the field of UMTS and communications systems.

Volume 1 Report also available (ISBN 9780108444517). Genomic medicine has developed from the sequencing of the human genome

Explore and advance bioinformatics and systems biology tools for crop breeding programs in this practical resource for researchers Plant biology and crop breeding have produced an immense amount of data in recent years, from genomics to interactome and beyond. Bioinformatics tools, which aim at analyzing the vast quantities of data produced by biological research and processes, have developed at a rapid pace to meet the challenges of this vast data trove. The resulting field of bioinformatics and systems biology is producing increasingly rich and transformative research. Bioinformatics for Plant Research and Crop Breeding offers an overview of this field, its recent advances, and its wider applications. Drawing on a range of analytical and data-science tools, its foundation on an in-silico platform acquired multi-omics makes it indispensable for scientists and researchers alike. It promises to become ever more relevant as new techniques for generating and organizing data continue to transform the field. Bioinformatics for Plant Research and Crop Breeding readers will also find: A focus on emerging trends in plant science, sustainable agriculture, and global food security Detailed discussion of topics including plant diversity, plant stresses, nanotechnology in agriculture, and many others Applications incorporating artificial intelligence, machine learning, deep learning and more Bioinformatics for Plant Research and Crop Breeding is ideal for researchers and scientists interested in the potential of OMICs, and bioinformatic tools to aid and develop crop improvement programs.