A synthesis of the results of receptor mapping in the human nervous system, including photographs clearly showing the distribution of specific receptors. Recognizes that the field is in a major transition period: receptor autoradiography has recently allowed the study of postmortem human brains, as well as those of experimental animals; and positron emission tomography is now allowing the study of live human brains. The information presented is therefore intended not only to be of use itself, but to serve as a background for the new information expected shortly. Annotation copyrighted by Book News, Inc., Portland, OR

Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing p

Glutamate is the most pervasive neurotransmitter in the central nervous system (CNS). Despite this fact, no validated biological markers, or biomarkers, currently exist for measuring glutamate pathology in CNS disorders or injuries. Glutamate dysfunction has been associated with an extensive range of nervous system diseases and disorders. Problems with how the neurotransmitter glutamate functions in the brain have been linked to a wide variety of disorders, including schizophrenia, Alzheimer's, substance abuse, and traumatic brain injury. These conditions are widespread, affecting a large portion of the United States population, and remain difficult to treat. Efforts to understand, treat, and prevent glutamate-related disorders can be aided by the identification of valid biomarkers. The Institute of Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop on June 21-22, 2010, to explore ways to accelerate the development, validation, and implementation of such biomarkers. Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System: Workshop Summary investigates promising current and emerging technologies, and outlines strategies to procure resources and tools to advance drug development for associated nervous system disorders. Moreover, this report highlights presentations by expert panelists, and the open panel discussions that occurred during the workshop.

In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg

Aging of the Autonomic Nervous System is the first book devoted to the aging of the autonomic nervous system. The book presents the most recent findings on topics such as general aspects of the autonomic nervous system, main neurotransmitter systems, age-dependent changes of neuroeffector mechanisms in target organs, and therapeutic perspectives. It also provides a comprehensive analysis of the possible consequences of these findings. Aging of the Autonomic Nervous System will be a useful volume for gerontologists and neuroscientists.

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Easily understood, up-to-date and clinically relevant, this book provides junior anaesthetists with an essential physiology resource.

The peripheral nervous system is usually defined as the cranial nerves, spinal nerves, and peripheral ganglia which lie outside the brain and spinal cord. To describe the structure and function of this system in one book may have been possible last century. Today, only a judicious selection is possible. It may be fairly claimed that the title of this book is not misleading, for in keeping the text within bounds only accounts of olfaction, vision, audition, and vestibular function have been omitted, and as popularly understood these topics fall into the category of special senses. This book contains a comprehensive treatment of the structure and function of peripheral nerves (including axoplasmic flow and trophic func tions); junctional regions in the autonomic and somatic divisions of the peripheral nervous system; receptors in skin, tongue, and deeper tissues; and the integrative role of ganglia. It is thus a handbook of the peripheral nervous system as it is usually understood for teaching purposes. The convenience of having this material inside one set of covers is already proven, for my colleagues were borrowing parts of the text even while the book was in manuscript. It is my belief that lecturers will find here the information they need, while graduate students will be able to get a sound yet easily read account of results of research in their area. JOHN 1. HUBBARD vii Contents SECTION I-PERIPHERAL NERVE Chapter 1 Peripheral Nerve Structure 3 Henry deF. Webster 3 1. Introduction .