Protein Targeting, Transport, and Translocation

Protein Targeting, Transport, and Translocation
Author :
Publisher : Elsevier
Total Pages : 441
Release :
ISBN-10 : 9780080480503
ISBN-13 : 0080480500
Rating : 4/5 (03 Downloads)

Synopsis Protein Targeting, Transport, and Translocation by : Ross Dalbey

Protein Targeting, Transport, and Translocation presents an in-depth overview on the topic of protein synthesis, covering all areas of protein science, including protein targeting, secretion, folding, assembly, structure, localization, quality control, degradation, and antigen presentation. Chapters also include sections on the history of the field as well as summary panels for quick reference. Numerous color illustrations complement the presentation of material. This book is an essential reference for anyone in biochemistry and protein science, as well as an excellent textbook for advanced students in these and related fields. - Basic principles and techniques - Targeting adn sorting sequences - Protein export in bacteria - Membrane protein integration into ER and bacterial membranes - Protein translocation across the ER - Disulfide bond formation in prokaryotes and eukaryotes - Quality control in the export pathway - Import of proteins into organelles - The secretory pathway - Vesicular transport - Spectacular color throughout

Trafficking Inside Cells

Trafficking Inside Cells
Author :
Publisher : Springer Science & Business Media
Total Pages : 459
Release :
ISBN-10 : 9780387938776
ISBN-13 : 038793877X
Rating : 4/5 (76 Downloads)

Synopsis Trafficking Inside Cells by : Nava Segev

This book covers the past, present and future of the intra-cellular trafficking field, which has made a quantum leap in the last few decades. It details how the field has developed and evolved as well as examines future directions.

Cells: Molecules and Mechanisms

Cells: Molecules and Mechanisms
Author :
Publisher : Axolotl Academic Publishing
Total Pages : 283
Release :
ISBN-10 : 9780985226114
ISBN-13 : 0985226110
Rating : 4/5 (14 Downloads)

Synopsis Cells: Molecules and Mechanisms by : Eric Wong

"Yet another cell and molecular biology book? At the very least, you would think that if I was going to write a textbook, I should write one in an area that really needs one instead of a subject that already has multiple excellent and definitive books. So, why write this book, then? First, it's a course that I have enjoyed teaching for many years, so I am very familiar with what a student really needs to take away from this class within the time constraints of a semester. Second, because it is a course that many students take, there is a greater opportunity to make an impact on more students' pocketbooks than if I were to start off writing a book for a highly specialized upper- level course. And finally, it was fun to research and write, and can be revised easily for inclusion as part of our next textbook, High School Biology."--Open Textbook Library.

Unconventional Protein Secretion

Unconventional Protein Secretion
Author :
Publisher : Humana
Total Pages : 0
Release :
ISBN-10 : 1493938029
ISBN-13 : 9781493938025
Rating : 4/5 (29 Downloads)

Synopsis Unconventional Protein Secretion by : Andrea Pompa

This volume presents relevant background information to understanding the molecular basis governing unconventional protein secretion (UPS), and in particular explores the latest techniques and protocols that have been successfully applied for the study of this topic. Detailed chapters include an overview of conventional and unconventional secretory pathways along with multidisciplinary approaches and methods used for UPS analysis in different organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Unconventional Protein Secretion: Methods and Protocols will be useful for all interested in the secretory pathway field as well as applications in cell biology, cell development, biomedical research, and healthcare.

The Golgi Apparatus

The Golgi Apparatus
Author :
Publisher : Springer Science & Business Media
Total Pages : 714
Release :
ISBN-10 : 9783211763100
ISBN-13 : 3211763104
Rating : 4/5 (00 Downloads)

Synopsis The Golgi Apparatus by : Alexander A. Mironov

This book summarizes all new data obtained after development of methods of Golgi complex sub fractionation, molecular biology and microscopy. It collects the full range of expertise, different points of view and different approaches. The book is devoted to molecular modes of the function of the Golgi apparatus as a whole, taking into account all experimental data. The book aims to make the functional organization of the Golgi apparatus more understandable.

Endoplasmic Reticulum

Endoplasmic Reticulum
Author :
Publisher : IOS Press
Total Pages : 172
Release :
ISBN-10 : 158603474X
ISBN-13 : 9781586034740
Rating : 4/5 (4X Downloads)

Synopsis Endoplasmic Reticulum by : A. Benedetti

The endoplasmic reticulum is a continuous membrane network in the cytosol, which encloses its internal compartment, the endoplasmic reticulum lumen. Several metabolic pathways are compartmentalised within the ER lumen, for example hydrolysis of glucose 6-phosphate, glucuronidation of endo- xenobiotics, posttranslational modification of proteins including redox reactions required for oxidative folding, oxidoreduction of steroid hormones, synthesis of ascorbate. Therefore, enzyme activities of these pathways depend on the special luminal microenvironment, on access to substrates and on release of products. However, in spite of great efforts, the molecular mechanism for the generation and maintenance of this special microenvironment still remains to be elucidated. Beside the well-known functions of the endoplasmic reticulum, such as calcium signaling and the synthesis of secretory proteins, recent findings underlined the importance of the intraluminal redox biochemistry and the role of membrane transporters. The field is currently undergoing extensive reappraisal, new transporters have been identified either molecular or functional level.The local synthesis and the membrane transport of redox active compounds (pro- and antioxidants) seem to be important not only in the disulfide bond formation, but also in the generation of intracellular proliferative/apoptotic signals. The different points of views in this publication help highlight the potential importance of several recently described phenomena, whose significance needs elucidation.

The Liver

The Liver
Author :
Publisher : John Wiley & Sons
Total Pages : 1156
Release :
ISBN-10 : 9781119436829
ISBN-13 : 1119436826
Rating : 4/5 (29 Downloads)

Synopsis The Liver by : Irwin M. Arias

Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.

Eukaryotic Membranes and Cytoskeleton

Eukaryotic Membranes and Cytoskeleton
Author :
Publisher : Springer
Total Pages : 170
Release :
ISBN-10 : 0387740201
ISBN-13 : 9780387740201
Rating : 4/5 (01 Downloads)

Synopsis Eukaryotic Membranes and Cytoskeleton by : Gáspár Jékely

The presence/absence of gene families with central roles in endomembrane and cytoskeleton dynamics in a variety of eukaryotic taxa and an understanding of eukaryote phylogeny allow the cellular machineries present in the last common ancestor of eukaryotes to be accurately reconstructed. Such a reconstruction is fundamental in order to understand eukaryotic diversification, since this is the ancestral cell from which all diversity arose. This book discusses the evolutionary origin and diversification of eukaryotic endomembranes and cytoskeleton from a cell biological and comparative genomic perspective.

Membrane Protein Assembly

Membrane Protein Assembly
Author :
Publisher : R. G. Landes
Total Pages : 300
Release :
ISBN-10 : WISC:89058926130
ISBN-13 :
Rating : 4/5 (30 Downloads)

Synopsis Membrane Protein Assembly by : Gunnar von Heijne