This volume constitutes the proceedings of the Fourth International Workshop on Materials Processing at High Gravity, held at Clarkson University, May 29 to June 2, 2000. There were 73 attendees from 16 countries. Since the topics extended well beyond materials processing, it was felt appropriate to name this proceedings "Centrifugal Processing." Processing by Centrifugation includes the traditional bench-scale centrifuges, as well as all rotating systems utilizing the centrifugal and Coriolis forces to provide unique performance. Centrifugation led to the formation of sticky porous Teflon membranes, as well as improved polymeric solar cells. Centrifugation on large equipment improved the chemical vapor deposition of diamond films, influenced the growth and dissolution of semiconductor crystals, and elucidated the influence of gravity on coagulation of colloidal Teflon. A million g centrifuge was constructed and used to study sedimentation in solids and to prepare compositionally graded materials and new phases. Rotation of a pipe about its axis allowed the casting of large-diameter metal alloy pipes as well as coating the interior of pipes with a cermet utilizing self-propagating high-temperature synthesis. Such coatings are highly corrosion and erosion resistant. Flow on a rotating disk was shown to be useful for process intensification, such as large-scale manufacturing of nano-particles, polymerization reactions, and heat & mass transfer. Several theoretical studies dealt with the influence of rotation on fluid convection on surfaces and in pipes, tubes, and porous media. These have applications to integrated-circuit chip manufacturing, alloy casting, oil production, crystal growth, and the operation of rotating machinery.

Centrifugal Separations in Biotechnology, Second Edition, is the only book on the market devoted to centrifugal separation in biotechnology. Key topics covered include a full introduction to centrifugation, sedimentation and separation; detailed coverage of centrifuge types, including batch and semi-batch centrifuges, disk-stack and tubular decanter centrifuges; methods for increasing solids concentration; laboratory and pilot testing of centrifuges; selection and sizing centrifuges; scale-up of equipment, performance prediction and analysis of test results using numerical simulation. Centrifugal Separations in Biotechnology, Second Edition, provides guidance on troubleshooting and optimizing centrifuges, and then goes on to explore the commercial applications of centrifuges in biotechnology. It gives detailed process information and data to assist in the development of particular processes from existing systems. It is of value to professionals in the chemical, bioprocess, and biotech sectors, and all those concerned with bioseparation, bioprocessing, unit-operations and process engineering. - Provides a comprehensive guide to centrifuges, their optimal development, and their operation in the biotechnology industry - Updated throughout based on developments in industrial applications and advances in our understanding of centrifugal separations in biotechnology - Discusses applications for the separation of proteins, DNA, mitochondria, ribosomes, lysosomes and other cellular elements - Includes new sections on use of optimal polymer dosage in waste treatment, new centrifuge designs for applications in algae processing, biopharma, and more

This volume constitutes the proceedings of the Fourth International Workshop on Materials Processing at High Gravity, held at Clarkson University, May 29 to June 2, 2000. There were 73 attendees from 16 countries. Since the topics extended well beyond materials processing, it was felt appropriate to name this proceedings "Centrifugal Processing." Processing by Centrifugation includes the traditional bench-scale centrifuges, as well as all rotating systems utilizing the centrifugal and Coriolis forces to provide unique performance. Centrifugation led to the formation of sticky porous Teflon membranes, as well as improved polymeric solar cells. Centrifugation on large equipment improved the chemical vapor deposition of diamond films, influenced the growth and dissolution of semiconductor crystals, and elucidated the influence of gravity on coagulation of colloidal Teflon. A million g centrifuge was constructed and used to study sedimentation in solids and to prepare compositionally graded materials and new phases. Rotation of a pipe about its axis allowed the casting of large-diameter metal alloy pipes as well as coating the interior of pipes with a cermet utilizing self-propagating high-temperature synthesis. Such coatings are highly corrosion and erosion resistant. Flow on a rotating disk was shown to be useful for process intensification, such as large-scale manufacturing of nano-particles, polymerization reactions, and heat & mass transfer. Several theoretical studies dealt with the influence of rotation on fluid convection on surfaces and in pipes, tubes, and porous media. These have applications to integrated-circuit chip manufacturing, alloy casting, oil production, crystal growth, and the operation of rotating machinery.

With contributions from biotechnologists and bioengineers, this ready reference describes the state of the art in industrial biopharmaceutical production, with a strong focus on continuous processes. Recent advances in single-use technology as well as application guidelines for all types of biopharmaceutical products, from vaccines to antibodies, and from bacterial to insect to mammalian cells are covered. The efficiency, robustness, and quality control of continuous production processes for biopharmaceuticals are reviewed and compared to traditional batch processes for a range of different production systems.

The first edition of Food Analysis: Theory and Practice was published in 1971 and was revised in 1978. The second edition was published in 1987, and in 1993 we found it necessary to prepare a third edition to reflect and cover the most recent advances in the field of food analysis. A complete revision of a book is an arduous and anguished task. The following are challenges that we wanted to address in this revision: to update the material without eliminating classic and time-preserved and honored methods used by the food analyst; to broaden and deepen the coverage and scope without increasing the size of the book; and to produce a textbook (for senior undergraduate and graduate students) with regard to objectives, scope, and outlay while providing a reference and resource for the worker and researcher in the field of food analysis. To meet those challenges we added much new material and took out practically the same amount of "rel atively outdated" material. Every chapter has been extensively updated and revised; many of the pictures in the previous editions were deleted and, whenever available and appropriate, were replaced by diagrams or flow sheets. In Part I we have expanded the seetions on sampling, preparation of sam pIes, reporting results, and reliability of analyses.

Uniquely integrates the theory and practice of key experimental techniques for bioscience undergraduates. Now includes drug discovery and clinical biochemistry.

Introduction General Principles of Sedimenting Centrifuges Batch Sedimenting Centrifuges Continous Sedimenting Centrifuges Applications of Sedimenting Centrifuges Continous-Feed Sedimentation General Principles of Filtering Centrifuges Batch Filtering Centrifuges Continuous Filtering Centrifuges Applications of Filtering Centrifuges Feed Acceleration Lab, Pilot, and Production Tests Centrifuge Selection and Sizing Optimization and Troubleshooting Kaolin Processing Dewatering of Compactible Solids Cake compaction theory Appendices Name Index Subject Index.

This long awaited second edition of a popular textbook has a simple and direct approach to the diversity and complexity of food processing. It explains the principles of operations and illustrates them by individual processes. The new edition has been enlarged to include sections on freezing, drying, psychrometry, and a completely new section on mechanical refrigeration. All the units have been converted to SI measure. Each chapter contains unworked examples to help the student gain a grasp of the subject, and although primarily intended for the student food technologist or process engineer, this book will also be useful to technical workers in the food industry

Modern Sample Preparation for Chromatography, Second Edition explains the principles of sample preparation for chromatographic analysis. A variety of procedures are applied to make real-world samples amenable for chromatographic analysis and to improve results. This book's authors discuss each procedure's advantages, disadvantages and their applicability to different types of samples, along with their fit for different types of chromatographic analysis. The book contains numerous literature references and examples of sample preparation for different matrices and new sections on green approaches in sample preparation, progress in automation of sample preparation, non-conventional solvents for LLE (ionic liquids, deep eutectic mixtures, and others), and more. - Presents numerous techniques applied for sample preparation for chromatographic analysis - Provides an up-to-date source of information regarding the progress made in sample preparation for chromatography - Describes examples for specific types of matrices, providing a guide for choosing the appropriate sample preparation method for a given analysis