What has prompted the shift toward sustainability in numerous financial areas? Can investors' mindsets be changed to embrace a long-term view? Can shareholders and activists play a greater role in encouraging financial actors to behave more responsibly? These are some of the relevant topics that are explored in this forward-looking set of essays.

Known by the Indians as "Broken Hand," Thomas Fitzpatrick was a trapper and a trailblazer who became the head of the Rocky Mountain Fur Company. With Jedediah Smith he led the trapper band that discovered South Pass; he then shepherded the first two emigrant wagon trains to Oregon, was official guide to Fremont on his longest expedition, and guided Colonel Phil Kearny and his Dragoons along the westward trails to impress the Indians with howitzers and swords. Fitzpatrick negotiated the Fort Laramie treaty of 1851 at the largest council of Plains Indians ever assembled. Among the most colorful of mountain men, Fitzpatrick was also party to many of the most important events in the opening of the West.

50 Studies Every Doctor Should Know presents summaries and analysis of 50 studies that have shaped the practice of medicine. Covering a wide array of topics - from dieting to cardiovascular disease, insomnia to obstetrics - this is a must-read for health care professionals and anyone who wants to learn about the data behind clinical practice.

This volume contains reviews which are based on a symposium, given th at the 30 meeting of The Phytochemical Society of North America, held at Laval University in Quebec City, Canada on August 11-15, 1990. During the past two decades, there have been major new developments in methods which can be applied toward the isolation, separation and structure determination of complex natural products. Therefore, the topic of this symposium, "Modem Phytochemical Methods", is a very timely one. The organizers of the symposium recognized that it would not be possible to cover in detail all new advances in phytochemical methodology. It was therefore decided to emphasize general reviews on recent developments of major separation techniques such as high performance liquid chromatography as well as supercritical fluid chromato graphy. In addition, advances in commonly used structure determination methods, mainly NMR and MS, are reviewed. Other topics include methodo logies of micro-sampling for isolation and analysis of trichome constituents as well as recent breakthroughs on biosynthetic studies of monoterpenes using "enriched" basal cells of trichomes. The volume concludes with a review of quantitative structure-activity relationship (QSAR) studies of biologically active natural products. In Chapter I, K. Hostettmann and his colleagues give a general review of recent developments in the separation of natural products with major emphasis on preparative separations of biologically active plant constituents. The authors present a comparison of droplet countercurrent chromatography (OCCC) with the highly rapid and more versatile centrifugal partition chromatography (CPC).